Mark A Latta

US Patent:

20080300340, Dec 4, 2008

Filed:

May 31, 2007

Appl. No.:

11/809248

Inventors:

Stephen M. Gross - Omaha NE, US
Mark A. Latta - Omaha NE, US

International Classification:

A61K 6/00

US Classification:

523120

Abstract:

Dental restorative composites having self-healing capabilities to repair discontinuities in the composite are provided. Dental restorative composites according to the present invention include a microsphere that encapsulates a monomer. When a fracture occurs, the microsphere is ruptured and the monomer fills the fracture. Depending on the monomer present in the microsphere, it is polymerized by a polymerization initiator or by an olefin metathesis catalyst present in the dental restorative composite. Self-healing dental restorative composites provide increased resistance to fracturing, and thus remain substantially intact for a longer period of time, preserving the remedial integrity of the dental repair or reconstruction.

US Patent:

20100272764, Oct 28, 2010

Filed:

Apr 27, 2010

Appl. No.:

12/768696

Inventors:

Mark A. Latta - Omaha NE, US
Stephen M. Gross - Omaha NE, US
William A. McHale - Collegeville PA, US

International Classification:

A61K 8/18
A61K 9/50
A61Q 11/00
A61K 9/20
A61K 9/48
A61K 9/68

US Classification:

424401, 424497, 424 49, 424464, 424451, 424440

Abstract:

The present invention is directed to compositions, products and methods useful for bone and tooth mineralization. The compositions comprise polymer microcapsules containing aqueous salt solutions. The shells of the microcapsules can be semi-permeable or impermeable. Solutions of calcium, fluoride and phosphate salts are particularly useful in the compositions of the invention. The microcapsules are preferably prepared by surfactant free inverse emulsion interfacial polymerization. Bone products include cements, scaffolds and bioactive glass. Dental products include pastes, gels, rinses and many other dental materials.

US Patent:

20110071234, Mar 24, 2011

Filed:

Sep 18, 2009

Appl. No.:

12/586233

Inventors:

Stephen M. Gross - Omaha NE, US
Mark A. Latta - Omaha NE, US

International Classification:

A61K 6/08

US Classification:

523116

Abstract:

Dental restorative formulations comprising two additives incorporated into the continuous phase of a dental material. One additive contains a capsule with a radical initiator. The other additive contains a capsule with one or more monomers and a radical accelerator. The dental restorative formulation is applied and polymerized to form a composite. When a disturbance occurs in the dental composite, the capsules of the additives rupture so that the radical accelerator of the second capsule decomposes the radical initiator of the first capsule to polymerize the one or more monomers of the second capsule thereby healing the dental composite. The radical accelerator controls the rate of decomposition of the radical initiator.

US Patent:

20110082232, Apr 7, 2011

Filed:

Oct 5, 2009

Appl. No.:

12/587279

Inventors:

Stephen M. Gross - Omaha NE, US
Mark A. Latta - Omaha NE, US

International Classification:

A61K 6/087

US Classification:

523115

Abstract:

Dental restorative formulations comprising an additive material and a capsule incorporated into the continuous phase of a dental material. The additive material includes one or more alkoxy groups and one or more vinyl groups. The capsule includes a catalyst and a molecule with one or more silanol groups. The dental restorative formulation is applied and polymerized to form a composite. When a disturbance occurs in the dental composite, the capsule ruptures so that the catalyst initiates a condensation reaction between the molecule with one or more silanol groups and the one or more alkoxy groups thereby healing the dental composite.

US Patent:

20130011453, Jan 10, 2013

Filed:

Sep 14, 2012

Appl. No.:

13/619128

Inventors:

Mark A. Latta - Omaha NE, US
Stephen M. Gross - Omaha NE, US
William A. McHale - Collegeville PA, US

Assignee:

Premier Dental Products Company - Plymouth Meeting PA

International Classification:

A61K 9/50
A61P 7/02
A61P 31/00
A61P 19/08
A61K 8/11
B01J 13/14
A61K 6/08
A61P 17/00
A61Q 5/00
A61Q 19/00
A61Q 3/00
A61P 29/00
A61Q 11/00

US Classification:

424401, 424497, 264 433

Abstract:

A microcapsule composition comprising at least one polymer substantially disposed as a semi-permeable shell around a buffered solution and at least one therapeutic agent, wherein the therapeutic agent permeates the shell, and wherein the composition is suitable for delivery to a mammal. This invention also provides related compositions, products and methods.

US Patent:

55020879, Mar 26, 1996

Filed:

May 16, 1994

Appl. No.:

8/240857

Inventors:

Louis H. Tateosian - York PA
Scott E. Shaffer - Jacobus PA
Mark A. Latta - York PA

Assignee:

Dentsply Research & Development Corp. - Milford DE

International Classification:

A61C 1308
A61C 1300
C08F12018
C08F12020

US Classification:

523115

Abstract:

A dental prosthesis includes polymeric material formed by heat curing a polymerizable composition having at least 5 percent by weight of at least one polymerizable Monomer having at least one acrylic moiety and a gram molecular weight of at least 200. The polymeric material is preferably formed by heat curing and has an unnotched Izod impact strength of at least 2. 5 and more preferably at least 3. 0 ft. lb/in as measured by a Modified ASTM D256, and a flexural fatigue life of at least 20,000 flexes to failure at 0. 1 inch deflection. Preferably the polymerizable monomer has a vapor pressure less than 5 mm Hg at 23. degree. C. A method of making a denture is provided which includes molding and polymerizing the polymerizable composition to form a denture. Preferably the polymerizable composition includes polymerizable compounds made up of at least 5 percent by weight of the acrylic Monomer having a gram molecular weight of at least 300 and less than 5 percent by weight of Volatile compounds and less than 2 percent by weight of Low Molecular Weight acrylic compounds having a gram molecular weight of less than 200.

US Patent:

55546650, Sep 10, 1996

Filed:

Apr 28, 1995

Appl. No.:

8/430705

Inventors:

Louis H. Tateosian - York PA
Scott E. Shaffer - Jacobus PA
Mark A. Latta - York PA

Assignee:

Dentsply Research & Development Corp. - Milford DE

International Classification:

C08F 246

US Classification:

522 30

Abstract:

A method of forming dental products, such as dentures, denture relines, dental crowns, dental bridges and dental restorative materials, temporary crown, temporary bridge, provisional crown or provisional bridge, from two polymerizable paste compositions each having a complimentary component of a free radical catalyst system and a polymerizable acrylic compound. One of these paste compositions includes an oxidizing agent and a stabilizer and the other includes a reducing agent as components of a redox catalyst system for free radical polymerization. These paste compositions are mixed in a static mixer to form a polymerizing paste composition, which is then shaped into a dental prosthesis. A handheld mixing dispenser useful in carrying out this method, includes a static mixing conduit, and two containers enclosing the polymerizable paste compositions. The static mixing conduit encloses a static mixing member.

US Patent:

20220387262, Dec 8, 2022

Filed:

Jul 29, 2022

Appl. No.:

17/816220

Inventors:

- Plymouth Meeting PA, US
William A. McHale - Collegeville PA, US
Mark A. Latta - Omaha NE, US

International Classification:

A61K 6/887
A61K 6/69
A61K 6/62
A61K 6/893
C08G 18/32
C08G 18/67

Abstract:

A composition comprising microcapsules functionalized with polymerizable functional groups on the surface of said microcapsules wherein the functional groups form covalent bonds with monomers in the continuous phase to enhance the mechanical properties of the composition.