Mark L Roth

US Patent:

20070155022, Jul 5, 2007

Filed:

Dec 30, 2005

Appl. No.:

11/325833

Inventors:

Mineo Yamakawa - Campbell CA, US
Narayan Sundararajan - San Francisco CA, US
Andrew Berlin - San Jose CA, US
Selena Chan - Sunnyvale CA, US
Xing Su - Cupertino CA, US
Lei Sun - Santa Clara CA, US
Mark Roth - Seattle WA, US

International Classification:

G01N 33/543
C12M 1/34

US Classification:

436518000, 977902000, 435287200

Abstract:

Embodiments of the present invention provide methods for determining the degenerate binding capabilities of antibodies. The methods provide information about degenerate binding capabilities without the use of involved procedures. Optionally, a molecule toward which an antibody exhibits degenerate binding ability may be identified through the use of a reporter, such as, a composite organic inorganic nanocluster (COIN). COINs are sensitive SERS (surface enhanced Raman spectroscopy) reporters capable of multiplex analysis of analytes.

US Patent:

48271217, May 2, 1989

Filed:

Feb 24, 1988

Appl. No.:

7/159154

Inventors:

Warren D. Vidrine - San Jose CA
Mark S. Roth - Palo Alto CA

Assignee:

Measurex Corporation - Cupertino CA

International Classification:

H01T 516
G01N 2141

US Classification:

250227

Abstract:

A system for detecting chemical characteristics within a material includes an optical fiber having a relatively short unclad sensor section for embedding in a material, a source of infrared radiation to direct infrared radiation into the fiber, and an optical decoder connected to the fiber to detect the spectrum of infrared radiation absorbed by the material in which the sensor section is embedded.