Mark C Schulz

US Patent:

6961401, Nov 1, 2005

Filed:

Jun 26, 2003

Appl. No.:

10/606664

Inventors:

Michael Nally - Ridgewood NJ, US
Mark Schulz - Hackettstown NJ, US

Assignee:

Sportcraft, Ltd. - Mt. Olive NJ

International Classification:

G01C021/00

US Classification:

377 242

Abstract:

A portable device, such as a pedometer or other device having a display portion that may be separated from an attachment portion for easier viewing. When separated, the display portion remains connected to the attachment portion to facilitate ease of re-attachment and for maintaining both parts of the device in an interconnected relationship. The attachment portion is removably connectable to a wearer. The display portion is extendably and retractably connected to the attachment module. A spring biased spool is provided in the attachment module to take up and release line connecting the display module to the attachment module. The display module has a receptacle formed on the back thereof. The attachment module has a protrusion extending from a back thereof for mating engagement with the receptacle when the display module and attachment module are in a retracted position.

US Patent:

7408008, Aug 5, 2008

Filed:

Dec 7, 2004

Appl. No.:

11/006145

Inventors:

Steve J. Coats - Quakertown PA, US
Dennis J. Hlasta - Doylestown PA, US
Mark J. Schulz - Skippack PA, US

Assignee:

Janssen Pharmaceutica, N.V. - Beerse

International Classification:

C08F 8/30

US Classification:

5253336, 549552

Abstract:

The invention is directed to compounds and methods of synthesizing hydroxyethlamino amides and their use in treatment of aspartyl protease mediated diseases and conditions.

US Patent:

7563781, Jul 21, 2009

Filed:

Jan 11, 2006

Appl. No.:

11/329642

Inventors:

Donald W. Ludovici - Quakertown PA, US
Richard W. Connors - Harleysville PA, US
Steven J. Coats - Quakertown PA, US
Li Liu - Doylestown PA, US
Bart L. De Corte - Southampton PA, US
Dana L. Johnson - Upper Black Eddy PA, US
Mark J. Schulz - Skippack PA, US

Assignee:

Janssen Pharmaceutica NV

International Classification:

C07D 487/04
C07F 9/40
A61K 31/5355
A61K 31/519
C07D 239/30
A61P 35/00
G01N 33/53
C07H 21/04
C12P 21/06
C12N 5/06
C07K 16/40
C12N 9/12

US Classification:

514 81, 5142611, 5142342, 51425212, 544118, 544244, 544254, 544326, 544329, 435 71, 435 691, 435194, 435348, 536 232, 5303911

Abstract:

The invention relates to the discovery of triazolopyrimidine derivatives of formula (I), which have been found to exhibit inhibitory activity against the serine-tyrosine and tyrosine kinases.

US Patent:

7649055, Jan 19, 2010

Filed:

Jul 1, 2008

Appl. No.:

12/165840

Inventors:

Steve J. Coats - Quakertown PA, US
Dennis J. Hlasta - Doylestown PA, US
Mark J. Schulz - Skippack PA, US

Assignee:

Janssen Pharmaceutica N.V. - Beerse

International Classification:

C08F 8/30

US Classification:

5253336, 549552

Abstract:

The invention is directed to compounds and methods of synthesizing hydroxyethylamino amides and their use in treatment of aspartyl protease mediated diseases and conditions.

US Patent:

7968710, Jun 28, 2011

Filed:

Mar 14, 2006

Appl. No.:

11/375407

Inventors:

Steven J. Coats - Quakertown PA, US
Alexey B. Dyatkin - Maple Glen PA, US
Wei He - Audubon PA, US
Joseph Lisko - Collegeville PA, US
Tamara A. Miskowski - Chalfont PA, US
Janet L. Ralbovsky - North Wales PA, US
Mark J. Schulz - Skippack PA, US

Assignee:

Janssen Pharmaceutica NV - Beerse

International Classification:

C07D 251/30
C07D 401/06
C07D 401/14
C07D 403/06
C07D 403/14
C07D 401/12
C07D 403/12
A61K 31/53
A61P 1/12
A61P 1/06
A61P 1/00

US Classification:

544223, 544220, 514245, 514241

Abstract:

The present invention relates to certain novel compounds of Formula (I):.

US Patent:

8168826, May 1, 2012

Filed:

Dec 3, 2009

Appl. No.:

12/630042

Inventors:

Steve J. Coats - Quakertown PA, US
Dennis J. Hlasta - Doylestown PA, US
Mark J. Schulz - Skippack PA, US

Assignee:

Janssen Pharamcuetica N.V. - Beerse

International Classification:

C07C 233/00
C07D 303/00
C07D 303/08
C08F 8/30

US Classification:

564185, 549512, 549552, 5253336

Abstract:

The invention is directed to compounds and methods of synthesizing hydroxyethylamino amides and their use in treatment of aspartyl protease mediated diseases and conditions.

US Patent:

8362247, Jan 29, 2013

Filed:

May 23, 2011

Appl. No.:

13/113751

Inventors:

Steven J. Coats - Quakertown PA, US
Alexey B. Dyatkin - Maple Glen PA, US
Wei He - Audubon PA, US
Joseph Lisko - Collegeville PA, US
Tamara A. Miskowski - Chalfont PA, US
Janet L. Ralbovsky - North Wales PA, US
Mark J. Schulz - Skippack PA, US

Assignee:

Janssen Pharmaceutica N.V. - Beerse

International Classification:

C07D 403/06
C07D 403/12
C07D 403/14
C07D 401/06
C07D 401/12
C07D 401/14
A61K 31/506
A61P 1/00
A61P 1/06

US Classification:

544309, 544310, 544311, 514269, 514274

Abstract:

The present invention relates to certain novel compounds of Formula (I):.

US Patent:

8383637, Feb 26, 2013

Filed:

Aug 4, 2005

Appl. No.:

11/197669

Inventors:

Ellen Baxter - Glenside PA, US
Francois Paul Bischoff - Vosselaar, BE
Robert E. Boyd - Horsham PA, US
Mirielle Braeken - Vlimmeren, BE
Steve Coats - Quakertown PA, US
Yifang Huang - Lansdale PA, US
Alfonzo D. Jordan - North Wales PA, US
Chi Luo - New Hope PA, US
Marc Hubert Mercken - Turnhout, BE
Serge Maria Aloysius Pieters - AR Hulst, NL
Allen B. Reitz - Lansdale PA, US
Charles H. Reynolds - Lansdale PA, US
Tina Morgan Ross - Royersford PA, US
Brett A. Tounge - Blue Bell PA, US
Mark J. Schulz - Skippack PA, US
Hans Louis Jos De Winter - Schilde, BE

Assignee:

Jansssen Pharmaceutica N.V. - Beerse

International Classification:

A61K 31/517
C07D 239/88
C07D 239/94
C07D 401/06
A61K 31/535
C07D 265/30

US Classification:

5142664, 5142662, 51426622, 5142315, 544284, 544292, 544106

Abstract:

The present invention is directed to novel 2-amino-3,4-dihydro-quinazoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of β-secretase, also known as β-site cleaving enzyme and BACE.