Mark W Stanley

US Patent:

59425377, Aug 24, 1999

Filed:

Aug 9, 1993

Appl. No.:

8/104417

Inventors:

A. Richard Chamberlin - Irvine CA
Richard J. Bridges - Mesa CA
Carl W. Cotman - Santa Ana CA
Mark S. Stanley - Pacifica CA

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

A61K 31575
A61K 3140

US Classification:

514423

Abstract:

A method of inhibiting the transport of a neurotransmitter away from the synapse comprising contacting a neurotransmitter transporter with a compound having the structure ##STR1## wherein ##STR2## or CONHR. sup. 3 in any combination and and wherein R. sup. 2 =OR. sup. 3, NR. sup. 3. sub. 2, alkyl, or substituted alkyl and R. sup. 3 =alkyl or substituted alkyl.

US Patent:

20200222667, Jul 16, 2020

Filed:

Mar 17, 2020

Appl. No.:

16/821159

Inventors:

- Yokneam, IL
Mark T. Stanley - Seal Beach CA, US
Christopher T. Beeckler - Brea CA, US

International Classification:

A61M 25/01

Abstract:

A guiding sheath assembly has a shaft that is operable to define more than one deflection curvature and defines a lumen to slidably receive a cardiovascular catheter. The guiding sheath assembly includes a proximal section, a distal section, and a stiffener member. The proximal section has a proximal shaft that defines a proximal lumen extending distally along a longitudinal axis to the distal section. The distal section has a distal shaft that defines a distal lumen that is configured to be biased (e.g., resiliently biased) laterally away from the longitudinal axis. The stiffener member is a rigid elongate member, such as an inner tubular member, that is configured to counteract the bias of the distal shaft. Longitudinal movement of the stiffener member relative to the distal section enables the operator to select and set a deflection curvature of the distal section.

US Patent:

20190254562, Aug 22, 2019

Filed:

Apr 29, 2019

Appl. No.:

16/398059

Inventors:

- Yokneam, IL
Meir Bar-Tal - Haifa, IL
George Kamin - Arcadia CA, US
Avram Dan Montag - Haifa, IL
Mark Stanley - Seal Beach CA, US

International Classification:

A61B 5/06
A61B 18/14
A61N 1/05
A61B 5/00
A61B 34/20

Abstract:

A catheter is responsive to external and internal magnetic field generators for generating position data of the catheter position and pressure data to determine pressured exerted on a distal end of the catheter when engaged with tissue, with a reduced number of sensing coils and reduced number of sensing coil leads for minimizing lead breakage and failure. The catheter includes a distal section adapted for engagement with patient tissue, where the distal section has a proximal portion, a distal portion and a flexible joint with a resilient member adapted to allow axial displacement and angular deflection between the proximal and distal portions of the distal section. The catheter may have three or less sensing coils with three or less leads, each transmitting signals between a respective sensing coil and the signal processor.

US Patent:

20190184138, Jun 20, 2019

Filed:

Dec 15, 2017

Appl. No.:

15/844301

Inventors:

- Yokneam, IL
Mark T. Stanley - Seal Beach CA, US
Daniele Ghidoli - Laguna Hills CA, US

International Classification:

A61M 25/01
A61B 5/042
A61B 18/14
A61M 25/00

Abstract:

A deflectable catheter with biased deflection characteristics has an elongated catheter body having a micro-injection molded spine that is configured with a center core, outwardly extending opposing struts, and one or more sets of longitudinally-aligned and discrete fins, wherein the struts resist deflection of the spine in a first plane and bias deflection of the spine in a second plane, wherein parameters of the discrete fins define deflection characteristics of the spine in the second plane.

US Patent:

20190167949, Jun 6, 2019

Filed:

Feb 4, 2019

Appl. No.:

16/267261

Inventors:

- Yokneam, IL
George Kamin - Arcadia CA, US
Mark Stanley - Seal Beach CA, US

International Classification:

A61M 25/01
A61B 5/06
A61B 5/00
A61B 18/14
A61B 18/12
A61B 5/05

Abstract:

A catheter is responsive to external and internal magnetic field generators for generating signals representing position and pressure data, with a reduced number of sensing coil leads for minimizing lead breakage and failure. The catheter includes a flexible joint with pressure sensing and position coils, at least pair of a pressure sensing coil and a position coil are serially connected. Methods of calibrating a catheter for position and pressure sensing, and detecting magnetic field interference with one catheter by another catheter or other metal or ferrous object advantageously use signals between two sets of sensors as a “back up” or “error check”.

US Patent:

20190037077, Jan 31, 2019

Filed:

Oct 4, 2018

Appl. No.:

16/151362

Inventors:

- Daly City CA, US
James Hvezda - Ancaster, CA
Rotem Maoz - Kohav-Yair, IL
Moshe Mishan - Tel-Aviv, IL
Doron Halevy - Tel-Aviv, IL
Mark W. Stanley - Los Angeles CA, US

International Classification:

H04M 3/523
H04M 3/51
G10L 13/04
G10L 15/22
G10L 15/18

Abstract:

According to one embodiment, a method for automating an interaction between a user and a contact center includes: receiving, by a processor, a natural language inquiry from the user; identifying, by the processor, a user intent from the natural language inquiry using a natural language processing module; loading, by the processor, a script corresponding to the user intent, the script comprising a plurality of fields of information associated with the user intent; filling at least one of the fields of information of the script based on a stored user profile; and supplying the filled fields of information to the contact center in accordance with the script. Some embodiments of the present invention relate to systems and methods for augmenting interactions between the user and the contact center.

US Patent:

20180220930, Aug 9, 2018

Filed:

Apr 2, 2018

Appl. No.:

15/943529

Inventors:

- Yokneam, IL
Meir Bar-Tal - Haifa, IL
George Kamin - Arcadia CA, US
Avram Dan Montag - Haifa, IL
Mark Stanley - Seal Beach CA, US

International Classification:

A61B 5/06
A61B 34/20
A61B 18/14
A61N 1/05
A61B 5/00

Abstract:

A catheter is responsive to external and internal magnetic field generators for generating position data of the catheter position and pressure data to determine pressured exerted on a distal end of the catheter when engaged with tissue, with a reduced number of sensing coils and reduced number of sensing coil leads for minimizing lead breakage and failure. The catheter includes a distal section adapted for engagement with patient tissue, where the distal section has a proximal portion, a distal portion and a flexible joint with a resilient member adapted to allow axial displacement and angular deflection between the proximal and distal portions of the distal section. The catheter may have three or less sensing coils with three or less leads, each transmitting signals between a respective sensing coil and the signal processor.

US Patent:

20180221624, Aug 9, 2018

Filed:

Apr 6, 2018

Appl. No.:

15/947250

Inventors:

- Yokneam, IL
Dror LEVY - Irvine CA, US
Yevgeny BONYAK - Haifa, IL
Mark STANLEY - Seal Beach CA, US

International Classification:

A61M 25/01
A61B 1/005
A61B 1/00

Abstract:

Apparatus, consisting of a probe, having a proximal end and a distal end, which is deflectable in first and second directions. The apparatus includes a probe manipulator, which is coupled to the proximal end of the probe and has first and second tactile control elements. The elements are operable by a user of the probe to deflect the distal end in the first and second directions, respectively, and are tactilely distinguishable one from the other.