Disclosed are antibodies specific for alpha-synuclein conformers and methods related thereto. For example, disclosed are methods of diagnosing a neurodegenerative monitoring a neurodegenerative disease treatment using the disclosed antibodies. Assays, kits, and solid supports related to alpha-synuclein and antibodies specific for alpha-synuclein are also disclosed.
Antigenic Mimics Of Discontinuous Epitopes Of Pathogen Recognized By Broadly Neutralizing Antibodies
The present invention relates to an anti-idiotypic polypeptide scaffold that includes two or more peptide sequences that mimic a discontinuous epitope of a pathogen that is recognized by or induces formation of a broadly neutralizing antibody. Using a fibronectin FNfn10 scaffold bearing two or more modified discontinuous loops, scaffolds that recognize broadly neutralizing antibodies in vitro and from patient serum have been identified. These scaffolds should induce an immune response or mobilize germline specificities to initiate their affinity maturation.
Anti-Glucosaminidase Passive Immunization For Staphylococcus Aureus Infections
The present invention is directed to a monoclonal antibody that binds specifically to a glucosaminidase and inhibits in vivo growth of Also disclosed are monoclonal antibody binding portions, recombinant or hybridoma cell lines, pharmaceutical compositions containing the monoclonal antibody or binding portions thereof, and methods of treating 5*. infection and osteomyelitis, and methods for introducing an orthopedic implant into a patient using the monoclonal antibody, binding portion, or pharmaceutical composition of the present invention.
Increased Production Of Thermus Aquaticus Dna Polymerase In E. Coli
Johnson & Johnson Clinical Diagnostic Systems, Inc. - Rochester NY
International Classification:
C12Q 168 C12N 121 C12N 1511 C12N 1563
US Classification:
435 6
Abstract:
The Thermus aquaticus gene encoding a thermostable DNA polymerase (Taq Pol) is altered in the N-terminus-encoding region to provide mutant genes with improved expression in E. coli.
Anti-Glucosaminidase Passive Immunization For Staphylococcus Aureus Infections
The present invention is directed to a monoclonal antibody that binds specifically to a glucosaminidase and inhibits in vivo growth of . Also disclosed are monoclonal antibody binding portions, recombinant or hybridoma cell lines, pharmaceutical compositions containing the monoclonal antibody or binding portions thereof, and methods of treating infection and osteomyelitis, and methods for introducing an orthopedic implant into a patient using the monoclonal antibody, binding portion, or pharmaceutical composition of the present invention.
Anti-Glucosaminidase Passive Immunization For Staphylococcus Aureus Infections
The present invention is directed to a monoclonal antibody that binds specifically to a glucosaminidase and inhibits in vivo growth of . Also disclosed are monoclonal antibody binding portions, recombinant or hybridoma cell lines, pharmaceutical compositions containing the monoclonal antibody or binding portions thereof, and methods of treating infection and osteomyelitis, and methods for introducing an orthopedic implant into a patient using the monoclonal antibody, binding portion, or pharmaceutical composition of the present invention.
Anti-Glucosaminidase Passive Immunization For Staphylococcus Aureus Infections
The present invention is directed to a monoclonal antibody that binds specifically to a glucosaminidase and inhibits in vivo growth of . Also disclosed are monoclonal antibody binding portions, recombinant or hybridoma cell lines, pharmaceutical compositions containing the monoclonal antibody or binding portions thereof, and methods of treating infection and osteomyelitis, and methods for introducing an orthopedic implant into a patient using the monoclonal antibody, binding portion, or pharmaceutical composition of the present invention.
Anti-Glucosaminidase Passive Immunization For Staphylococcus Aureus Infections
- Rochester NY, US Mark A. SULLIVAN - Fairport NY, US John L. DAISS - Rochester NY, US
International Classification:
C07K 16/12 C07K 16/40 A61K 39/00
Abstract:
The present invention is directed to a monoclonal antibody that binds specifically to a glucosaminidase and inhibits in vivo growth of . Also disclosed are monoclonal antibody binding portions, recombinant or hybridoma cell lines, pharmaceutical compositions containing the monoclonal antibody or binding portions thereof, and methods of treating infection and osteomyelitis, and methods for introducing an orthopedic implant into a patient using the monoclonal antibody, binding portion, or pharmaceutical composition of the present invention.
Dr. Sullivan graduated from the Cornell University Weill Medical College in 1972. He works in Arlington, MA and specializes in Gastroenterology. Dr. Sullivan is affiliated with Lahey Hospital & Medical Center.
Dr. Sullivan graduated from the Albert Einstein College of Medicine at Yeshiva University in 1988. He works in Fairfield, CA and specializes in Family Medicine. Dr. Sullivan is affiliated with NorthBay Medical Center and Sutter Santa Rosa Regional Hospital.
Dr. Sullivan graduated from the University of Washington SOM in 2003. He works in Seattle, WA and specializes in Occupational Medicine and Pain Management. Dr. Sullivan is affiliated with Harborview Medical Center and University Of Washington Medical Center.
Mr. Sullivan works in Billings, MT and specializes in Orthopaedic Surgery. Mr. Sullivan is affiliated with Billings Clinic Hospital and Saint Vincent Healthcare.
Oct 2011 to Oct 2012 Architect & SME, National Aeronautics and Space AdministrationOCIO), Defense Security Service (DSS Alexandria, VA Jul 2010 to Mar 2011 Chief Information Security Officer (CISO), GS-15, Office of the Chief Information OfficerTechnical Security Branch Chantilly, VA Jun 2007 to Jun 2010 Deputy ChiefNRO Chantilly, VA 2006 to 2010 Security Engineer & ManagerVulnerability Assessment Program Technology Chantilly, VA Aug 2006 to Jun 2007 ChiefLtCol/GS Seoul, KR Jul 2004 to Jul 2006 Chief of SecurityThe Wirefree Network Wireless Internet Service Provider (WISP)
Aug 2002 to Jul 2004 FounderNaval Postgraduate School Monterey, CA Jun 2002 to Jul 2004 StudentNaval Postgraduate School Monterey, CA 2004 to 2004 StudentThe Wirefree Network (WISP) Salinas, CA 2002 to 2004 Founder & CEONetwork Control Center Schriever AFB, CO May 2000 to Jun 2002 Chief50th Communications Squadron Schriever AFB, CO 2000 to 2002 Chief, Network/Space Operations50th Space Wing Maxwell AFB, AL Mar 2000 to May 2000 Also served as the OfficerVarious
Sep 1989 to Mar 2000 Enlisted Communications Electronics TechnicianUS Air Force
1989 to 2000 Electronics Technician
Education:
Naval Postgraduate School Monterey, CA 2004 Master of Science in Computer ScienceUniversity of Maryland, University College 2000 Bachelor of Science in Computer StudiesCommunity College of the Air Force 1999 Associate of Applied Science in Electronic Systems TechnologyUniversity of Maryland, University College 1999 Associate of Arts in Business Management
Apr 2012 to 2000 Service and Training ManagerCloverwood Retirement Estate Pittsford, NY Feb 2010 to Jun 2012 Team LeadOld Navy Henrietta, NY Jun 2011 to Apr 2012 Merchandise SpecialistMULTICULTURAL
May 2008 to Aug 2010 Bunk Leader/Arts and Crafts Director
Education:
Nazareth College of Rochester May 2012 B.S. in Business AdministrationGenesee Community College May 2009 A.S. in Business Administration
Skills:
Retail Management, Sales, Team Building, Communication, Training
Total Civil Construction & Engineering Lanham-Seabrook, MD Apr 2013 to Oct 2013 Tractor Trailer DriverTrillium Drivers Solutions Kalamazoo, MI Oct 2012 to Jan 2013 Tractor TrailerPCm Services Beltsville, MD May 2012 to Sep 2012 TracCenterline Drivers Santa Ana, CA Apr 2011 to Mar 2012 Truck Driver / Tractor TrailerAction Delivery Service Lanham, MD Dec 2010 to Jan 2011 Truck Driver / Tractor TrailerH.R. Department Laurel, MD Jan 2009 to Sep 2010 Truck Driver / Tractor Trailer / Shuttle BusKris Reardon Capitol Heights, MD Oct 2008 to Dec 2008 Truck Driver / Tractor TrailerFolcomer Equipment Corp Upper Marlboro, MD May 2008 to Sep 2008 Truck Driver / Tractor Trailer / Low-BoyGood Deale Bluegrass Shop
Sep 2005 to Apr 2008 Self/OwnerVentrsca & Sons College Park, MD Jun 2005 to Aug 2005 Truck Driver / Tractor Trailer / Low-Boy
Education:
Parkdale Sr. High / North American Training Acad. Newark, DE 1975 to 1979 High School Diploma- Tech School in General Studies / Tractor Trailer Driving 1980
Mar 2011 to Jul 2012 General Counsel, Chief Compliance Officer & SecretaryMEDQUIST Mount Laurel, NJ Jul 2004 to Jul 2012 General Counsel, Chief Compliance Officer & SecretaryMEDQUIST Franklin, TN Mar 2003 to Jul 2012 General CounselMEDQUIST
2010 to 2010 Provided legal counselMEDQUIST
Mar 2003 to Jul 2004 Associate General CounselPEPPER HAMILTON LLP Philadelphia, PA 2000 to 2003 AttorneyDRINKER BIDDLE & REATH LLP Princeton, NJ 1998 to 2000 AttorneyHONORABLE PHILIP S. CARCHMAN
1997 to 1998 Law Clerk in the Appellate Division of the New Jersey Superior CourtBaltimore Public School System Baltimore, MD 1993 to 1994 Middle school special education teacher
Education:
RUTGERS UNIVERSITY SCHOOL OF LAW Camden, NJ 1997 Juris DoctorUNIVERSITY OF PENNSYLVANIA Philadelphia, PA 1989 to 1993 BA
LabTech Software Tampa, FL Jan 2011 to May 2012 Regional Sales ManagerOPNET Technologies Bethesda, MD Aug 2007 to Jul 2010 Senior Account ExecutiveNumara Software Tampa, FL Jan 2005 to Aug 2007 Senior Technical Account ExecutiveComputer Associates Tampa, FL May 2003 to Jan 2005 Sales ExecutiveCGI Information Systems, Inc Dallas, TX Sep 2001 to Apr 2003 Territory Sales RepresentativeKnowledge Management Software, Inc Clearwater, FL Aug 1999 to Sep 2001 Account Executive
Education:
Seminole College Sanford, FL 1985 Associate of Arts
Chandler, AzVoiceBroadcastingpros.com I have provided marketing services, resources and leads since 2001. We have 3 different marketing sites: Vipdiscountleads.com -- Voicebroadcastingpros.com ... I have provided marketing services, resources and leads since 2001. We have 3 different marketing sites: Vipdiscountleads.com -- Voicebroadcastingpros.com --- RhinoEmailer.com (coming soon)
Truly honest marketing consultation for over 9 years. Call me ... I will increase your ROI, almost...
Englewood, COOver twenty years of experience in training, employment coaching, leadership development, recruiting and managing the human asset in the workplace.
... Over twenty years of experience in training, employment coaching, leadership development, recruiting and managing the human asset in the workplace.
Additionally, I have an extensive background in retail store/operations management (7+ years of experience), business development, program...
Denver, ColoradoPresident at Multi Media Marketing Solutions Past: Senior Account Executive at Consolidated Graphics, Senior Vice President of Sales at... Always up for an adventure.
California Institute of Technology - Mathematics, University of Washington - Mathematics
Mark Sullivan
Work:
Trane - Service Technician -Team Lead (2009)
Education:
Spotsylvania High - General Studies
Relationship:
Married
Tagline:
Love my life.... I have a great family and good friends.
Bragging Rights:
2 kids and a beautiful wife.
Mark Sullivan
Work:
Integrity Network Solutions - Senior Systems Engineer (2010) Aurora Health Care - Senior Systems Engineer (2006-2010) ESI Technoloy Advisors - Senior Systems Engineer (2002-2006)
Mark Sullivan
Work:
The Japan Exchange and Teaching Program - Instructor
Education:
University of Texas at Austin - Communications and Japanese
Mark Sullivan
Work:
University of Washington - MD
Education:
University of Washington - MD
Mark Sullivan
Work:
PCWorld
About:
I am a big game hunter. I'm friends with lots of famous people, but don't choose to be famous myself.
Tagline:
I'm trying to fit in.
Mark Sullivan
Work:
Sometimes
Education:
Some
Tagline:
Unknown
Youtube
Aero-TV: Adventures in Gas Ballooning - Mark ...
One Of The Most Amazing Aspects About Ballooning Are The Folks Who Are...
Category:
Autos & Vehicles
Uploaded:
02 Feb, 2011
Duration:
10m 18s
Mark Sullivan leads the Jam
Fiddle Champion Mark Sullivan leads the Saturday night jam at the Oran...
Category:
Music
Uploaded:
29 Oct, 2007
Duration:
9m 35s
MARK O SULLIVAN-SHE STOOD THERE LAUGHING
TAKEN FROM THE ALBUM FRAGMENTS FROM A LONG COUNTRY
Category:
Music
Uploaded:
15 Sep, 2008
Duration:
5m 36s
The Auld Fiddler (Mark Sullivan on fiddle & Q...
Mark was the headliner and lead fiddle instructor & Quinn taught a Cel...
Category:
Music
Uploaded:
13 Apr, 2009
Duration:
1m 54s
Mark Sullivan and Quinn Bachand play The Butl...
Mark and Quinn play a couple of tunes, The Butlers of Glen Avenue (Ton...
Category:
Music
Uploaded:
23 Apr, 2009
Duration:
2m 19s
Mark Sullivan (Le Rossignol)
Mark Sullivan (3x Canadian Fiddle Champion) and Geoff Horrocks perform...
omcasts Anna Gohmann ... Jerry Goldfeder ... Nicole Gill ... Melanie Fonder Kaye Mark Sullivan (h/t Teresa Sullivan) Joyce Li, policy adviser to the NYC deputy mayor for operations London Evening Standard editor George Osborne is 49 PhRMAs Sarah Sutton is 31
Facebook is pouring money into AI research to teach chatbots to converse like humans. Facebooks virtual assistant M may have flopped, but it continues to invest heavily in chatbot research. (Mark Sullivan / Fast Company)
Date: Sep 19, 2019
Category: Technology
Source: Google
ICE arrests nearly 150 meat plant workers in latest immigration raid in Ohio
We are honored to be selected by ICE to participate in this program, Fresh Mark human resources director Mark Sullivan said in the news release. For nearly a decade, Fresh Mark has proactively partnered with the government to ensure the integrity of our workforce and the IMAGE program will be a t
Date: Jun 20, 2018
Category: Headlines
Source: Google
Readers weigh in on Pogue's Apple HomePod listening test
They enlistedNTi Audio AG, a manufacturer of acoustics testing equipment. The company was kind enough to loan us a testing device, software, and a special microphone so that we could test the HomePod in a real-life natural habitatmy living room, writes Mark Sullivan. The companys Brian MacMill
Date: Feb 16, 2018
Category: Technology
Source: Google
The completely redesigned iPhone 8 could cost a boatload
The upcoming "special 10th anniversary edition" of the iPhone is expected to cost more than $1,000, reports Fast Company's Mark Sullivan, in a report that lines up with many of the rumors coming out of Apple's Asian supply chain.
Date: Feb 08, 2017
Category: Sci/Tech
Source: Google
Bowe Bergdahl makes first appearance in military court, enters no plea
"We've heard wildly different results and comments from people as high up as the national security adviser to President Obama, who said that Bowe Bergdahl had served with honor and distinction", said Mark Sullivan, an attorney in Raleigh who is also a retired colonel in the U.S. Army Reserve.
Date: Dec 27, 2015
Category: Entertainment
Source: Google
Sanders data controversy spotlights powerful gatekeeper
NGP VAN began life humbly enough as the Voter Activation Network. It was the late 1990s, and Mark Sullivan, an operative for the Senate campaign of Iowas Tom Harkin, couldn't find a good software solution. So he built his own. The VAN's advantage was that campaign records once thought of as disposa
Date: Dec 20, 2015
Category: U.S.
Source: Google
New breaches revealed in report that says Secret Service is 'in crisis'
Congressional investigators criticized testimony from former Secret Service director Mark Sullivan after the April 2012 scandal in which 13 agents were implicated in bringing prostitutes back to their hotel before the presidents arrival in Colombia.