Mark D Yeager

US Patent:

7718182, May 18, 2010

Filed:

Jan 17, 2006

Appl. No.:

11/795538

Inventors:

Rosemarie Kelly - Westfield NJ, US
Loren D. Schultz - Harleysville PA, US
Mark A. Miller - Wyndmoor PA, US
Mark D. Yeager - Saddle River NJ, US
Tessie McNeely - Gwynedd Valley PA, US

Assignee:

Merck Sharp & Dohme Corp. - Rahway NJ

International Classification:

A61K 39/085
C12P 21/04
C07H 21/02
C07H 21/04
C07K 14/31

US Classification:

4242431, 4241851, 4241921, 536 231, 536 235, 536 237, 435 691, 435 695, 435 697, 530350

Abstract:

The present invention features polypeptides comprising an amino acid sequence structurally related to SEQ ID NO: 1 or a fragment thereof, AhpC-AhpF compositions, and uses of such polypeptides and compositions. SEQ ID NO: 1 has a full length AhpC sequence. A derivative of SEQ ID NO: 1 containing an amino His-tag and three additional carboxyl amino acids was found to produce a protective immune response against.

US Patent:

20100203588, Aug 12, 2010

Filed:

Mar 9, 2010

Appl. No.:

12/720076

Inventors:

Rosemarie Kelly - Westfield NJ, US
Loren D. Schultz - Harleysville PA, US
Mark A. Miller - Wyndmoor PA, US
Mark D. Yeager - Saddle River NJ, US
Tessie McNeely - Gwynedd Valley PA, US

International Classification:

C12P 21/00
C12N 15/31
C12N 15/63
C12N 1/00

US Classification:

435 691, 536 237, 4353201, 435243

Abstract:

The present invention features polypeptides comprising an amino acid sequence structurally related to SEQ ID NO: 1 or a fragment thereof, AhpC-AhpF compositions, and uses of such polypeptides and compositions. SEQ ID NO: 1 has a full length AhpC sequence. A derivative of SEQ ID NO: 1 containing an amino His-tag and three additional carboxylamino acids was found to produce a protective immune response against

US Patent:

20110135680, Jun 9, 2011

Filed:

Oct 15, 2010

Appl. No.:

12/905584

Inventors:

Langzhou Song - Freehold NJ, US
Lynda G. Tussey - Princeton NJ, US
Alan R. Shaw - Doylestown PA, US
Robert S. Becker - Nazareth PA, US
Yi Zhang - Edison NJ, US
Scott W. Umlauf - Pennington NJ, US
David N. Taylor - Princeton NJ, US
Ge Liu - East Brunswick NJ, US
Mark D. Yeager - Allendale NJ, US

International Classification:

A61K 39/385
C07K 14/195
C07K 19/00
A61K 39/00
A61P 37/04
B82Y 5/00

US Classification:

4241931, 530350, 4241841, 977773, 977906

Abstract:

Compositions that include Toll-like Receptor 5 agonists and at least a portion of at least one viral antigen can be employed in methods that stimulate an immune response in a subject, in particular, a protective immune response in a subject. Compositions can be associated with particles and employed in the methods in relatively low doses to provide protective immunity to viral infection.

US Patent:

61123188, Aug 29, 2000

Filed:

Aug 11, 1997

Appl. No.:

8/909403

Inventors:

Norman P. Jouppi - Palo Alto CA
Joel J. McCormack - Boulder CO
Larry D. Seiler - Boylston MA
Mark O. Yeager - West Groton MA

Assignee:

Digital Equipment Corporation - Maynard MA

International Classification:

H02H 305
H03K 19003
H04B 174

US Classification:

714 47

Abstract:

An apparatus and method for counting event signals generated by a computer system is described. The event signals are indicative of the performance of the computer system. Programmable logic enhances the functionality of performance counters by enabling the system user to specify, during the execution of an application program, which event signals to count. The system user can dynamically configure the programmable logic to select a subset of the event signals generated by the computer system, and to combine the selected subset of event signals to generate a new event signal that can be counted. Other new event signals can be generated by the programmable logic from the selected subset of event signals. A user of the computer system can dynamically make the selection of any one of the new event signals for counting.