Sydney Welt - New York NY Gerd Ritter - New York NY Leonard Cohen - New York NY Clarence Williams - New York NY Elizabeth Carswell Richards - New York NY Mary John - New York NY Lloyd J. Old - New York NY
Assignee:
Ludwig Institute for Cancer Research - London Sloan-Kettering Institute for Cancer Research - NY
International Classification:
A61K 5100 A61K 4900 A61K 3514
US Classification:
424 149
Abstract:
The invention involves the therapeutic use of humanized antibodies, fragments, etc. , which bind to the antigen A33. These antibody molecules are useful in the treatment of various neoplasias, including colon cancer. Various modes of administration, and doses are described.
Methods Of Treating Colon Cancer Utilizing Tumor-Specific Antibodies
Sydney Welt - New York NY Gerd Ritter - New York NY Leonard Cohen - New York NY Clarence Williams - New York NY Elizabeth Carswell Richards - New York NY Mary John - New York NY Lloyd J. Old - New York NY
Assignee:
Ludwig Institute for Cancer Research - New York NY
International Classification:
A61K 39395 A61K 3900
US Classification:
4241561
Abstract:
This invention relates to methods of reducing the effects of colon cancer tumors. Various agents are conjugated to monoclonal antibodies which are specific for colon cancer cells. The conjugates are administered to patients having colon cancer such that the effects of the cancer are reduced.