Mary Beth Ryan

US Patent:

8394378, Mar 12, 2013

Filed:

Sep 26, 2011

Appl. No.:

13/245299

Inventors:

John Kehoe - Radnor PA, US
Jennifer Lee Gardiner - Seattle WA, US
Tatiana Ort - Radnor PA, US
Kristen Picha - Radnor PA, US
Mary Ryan - Radnor PA, US
John Wheeler - Radnor PA, US

Assignee:

Janssen Biotech, Inc. - Horsham PA

International Classification:

A61K 39/00
C07K 16/00
C07K 16/46

US Classification:

4241331, 5303871, 5303873, 53038825

Abstract:

The present invention relates to antibodies against human collagen II, polypeptides and polynucleotides encoding human collagen II antibodies or fragments thereof, and methods of making and using the foregoing.

US Patent:

8501907, Aug 6, 2013

Filed:

Nov 19, 2010

Appl. No.:

12/950240

Inventors:

Robert Jordan - Thorton PA, US
David Knight - Berwyn PA, US
Randall Brezski - Spring House PA, US
Mary Ryan - Spring House PA, US
Diane Petrone - Chesterbrook PA, US

Assignee:

Janssen Biotech, Inc. - Horsham PA

International Classification:

A61K 38/00
C07K 14/00

US Classification:

530300, 530327

Abstract:

The invention relates to antibody compositions and use of the composition to detect disease processes associated with elaboration of proteases. The reagents are directed to assessing an IgG breakdown product that is the result of such proteolytic cleavage. The invention further relates to the use of a therapeutic immunospecific for IgG protease cleavage products to restore effector function to antibody compositions that are subject to protease cleavage.

US Patent:

20090155280, Jun 18, 2009

Filed:

Aug 4, 2008

Appl. No.:

12/185333

Inventors:

Robert Jordan - Radnor PA, US
Diane D. Petrone - Radnor PA, US
Mary Ryan - Radnor PA, US

International Classification:

A61K 39/395
C07K 16/18
A01K 67/027
G01N 33/53

US Classification:

4241391, 5303879, 800 8, 435 71, 435 792

Abstract:

The invention relates to antibody compositions and use of the composition to detect disease processes associated with elaboration of proteases. The reagents are directed to assessing an IgG breakdown product that is the result of such proteolytic cleavage. The invention further relates to the use of a therapeutic immunospecific for IgG breakdown products retaining antigen binding but having lost effector functions.

US Patent:

20120082622, Apr 5, 2012

Filed:

Sep 26, 2011

Appl. No.:

13/245349

Inventors:

Michael Naso - Radnor PA, US
Mary Ryan - Radnor PA, US

International Classification:

A61K 49/00
C12N 15/63
C07K 14/47
C12P 21/02
C12N 5/10
G01N 33/566
C12N 1/21
C12N 1/15
C12N 1/19
C12N 15/12
C07K 16/18

US Classification:

424 92, 536 235, 4353201, 530324, 435 691, 5303879, 436501, 435 71, 4352523, 43525233, 43525235, 4352572, 43525231, 4352541, 4352542, 43525421, 43525422, 4352543, 435348, 435358, 435365, 435367, 435354, 435357, 435352, 435419, 435325

Abstract:

Isolated polynucleotides encoding CCL17 (CynoCCL17), polypeptides obtainable from expression of these polynucleotides, recombinant cells, and methods of use are disclosed.

US Patent:

20130239238, Sep 12, 2013

Filed:

Mar 14, 2013

Appl. No.:

13/804357

Inventors:

David Knight - Berwyn PA, US
Randall Brezski - Spring House PA, US
Mary Ryan - Spring House PA, US
Diane Petrone - Chesterbrook PA, US

Assignee:

JANSSEN BIOTECH INC. - Horsham PA

International Classification:

C07K 16/42
C07K 7/08

US Classification:

800 8, 530400, 530363, 5303873, 4241391, 4241301, 5303879, 530327, 530409

Abstract:

The invention relates to antibody compositions and use of the composition to detect disease processes associated with elaboration of proteases. The reagents are directed to assessing an IgG breakdown product that is the result of such proteolytic cleavage. The invention further relates to the use of a therapeutic immunospecific for IgG protease cleavage products to restore effector function to antibody compositions that are subject to protease cleavage.

US Patent:

20220348647, Nov 3, 2022

Filed:

Jun 29, 2022

Appl. No.:

17/853218

Inventors:

- Horsham PA, US
Alfred Del Vecchio - Spring House PA, US
John Kehoe - Spring House PA, US
Eilyn Lacy - Spring House PA, US
Lynne Murray - Melbourn, GB
Mary Ryan - Spring House PA, US
John Wheeler - Spring House PA, US
Brian Whitaker - Spring House PA, US
Alexey Teplyakov - Spring House PA, US

International Classification:

C07K 16/24

Abstract:

The present invention relates to antibodies specifically binding CCL17, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.

US Patent:

20210017267, Jan 21, 2021

Filed:

Oct 1, 2020

Appl. No.:

17/060362

Inventors:

- Horsham PA, US
Alfred Del Vecchio - Spring House PA, US
John Kehoe - Spring House PA, US
Eilyn Lacy - Spring House PA, US
Lynne Murray - Melbourn, GB
Mary Ryan - Spring House PA, US
John Wheeler - Spring House PA, US
Brian Whitaker - Spring House PA, US
Alexey Teplyakov - Spring House PA, US

International Classification:

C07K 16/24

Abstract:

The present invention relates to antibodies specifically binding CCL17, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.

US Patent:

20180171007, Jun 21, 2018

Filed:

Dec 8, 2017

Appl. No.:

15/835529

Inventors:

- Horsham PA, US
Alfred Del Vecchio - Spring House PA, US
John Kehoe - Spring House PA, US
Eilyn Lacy - Spring House PA, US
Lynne Murray - Melbourn, GB
Mary Ryan - Spring House PA, US
John Wheeler - Spring House PA, US
Brian Whitaker - Spring House PA, US
Alexey Teplyakov - Spring House PA, US

International Classification:

C07K 16/24
A61K 39/00

Abstract:

The present invention relates to antibodies specifically binding CCL17, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.