Matthew W Jeffries

age ~53

from Indianapolis, IN

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Also known as:

Matthew Wesley Jeffries
Matt W Jeffries
Moumita Jeffries

Phone and address:: 6511 Calla Lily Dr, Indianapolis, IN 46237
3178850099

Connected to:

Matthew Jeffries Phones & Addresses

6511 Calla Lily Dr, Indianapolis, IN 46237 • 3178850099
Arvada, CO
712 Woodtop Rd, Wilmington, DE 19804
Greenwood, IN
619 Pole Line Rd, Davis, CA 95616 • 5307565865
Concord, CA

Resumes

Biotechnology At Eli Lilly

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Location:

Indianapolis, IN

Industry:

Pharmaceuticals

Work:

Dupont-Merck Pharmaceuticals 1997 - 2001
Virologist
Eli Lilly and Company 1997 - 2001
Biotechnology at Eli Lilly

Education:

University of California, Davis 1994 - 1997
Master of Science, Masters Indiana University Bloomington 1991 - 1994
Bachelors, Bachelor of Science, Microbiology

Skills:

Drug Discovery
Infectious Diseases
Immunology
Biomarkers
Molecular Biology
Biotechnology
Mammalian Cell Protein Expression
Bioreactor Operation
Protein Expression

Matthew Jeffries

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Matthew Jeffries

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Location:

United States

Us Patents

In Vitro System For Replication Of Rna-Dependent Rna Polymerase (Rdrp) Viruses
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US Patent:

20030175683, Sep 18, 2003
Filed:

Jan 31, 2002
Appl. No.:

10/066130
Inventors:

Robert King - West Chester PA, US
Matthew Jeffries - Indianapolis IN, US
Claudio Pasquinelli - Media PA, US
International Classification:

C12Q001/70
G01N033/53
G01N033/537
G01N033/543
C12N007/00
C12N007/01
C12N005/00
C12N005/02
C12P019/34
US Classification:

435/005000, 435/007100, 435/235100, 435/325000, 435/007940, 435/091100
Abstract:

An in vitro method to conduct genomic replication of the viral genomes of viruses that utilize RNA-dependent RNA polymerase for replication (RDRP viruses), such as HCV. The method employs a construct comprising the 3′ and 5′ untranslated regions (UTRs) of the viral genome which are operably linked on the 5′ and 3′ ends of a reporter sequence, in antisense orientation, such that when viral replication is occurring within the cell which produces RDRP, the reporter protein will be made. The method of the invention provides an efficient means for measuring genomic replication in RDRP viruses, and also for the rapid screening of compounds for their ability to inhibit genomic replication of RDRP viruses, including the virus (HCV).

In Vitro System For Replication Of Rna-Dependent Rna Polymerase (Rdrp) Viruses
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US Patent:

20040126388, Jul 1, 2004
Filed:

Dec 12, 2003
Appl. No.:

10/734801
Inventors:

Robert King - West Chester PA, US
Matthew Jeffries - Wilmington DE, US
Claudio Pasquinelli - Media PA, US
International Classification:

C12Q001/70
A61K039/29
US Classification:

424/189100, 435/005000
Abstract:

An in vitro method to conduct genomic replication of the viral genomes of viruses that utilize RNA-dependent RNA polymerase for replication (RDRP viruses), such as HCV. The method employs a construct comprising the 3′ and 5′ untranslated regions (UTRs) of the viral genome which are operably linked on the 5′ and 3′ ends of a reporter sequence, in antisense orientation, such that when viral replication is occurring within the cell which produces RDRP, the reporter protein will be made. The method of the invention provides an efficient means for measuring genomic replication in RDRP viruses, and also for the rapid screening of compounds for their ability to inhibit genomic replication of RDRP viruses, including the Hepatitis C virus (HCV).