Matthew S Jeffries

age ~45

from Bel Air, MD

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Also known as:

Matthew Scott Jeffries
Matt S Jeffries

Connected to:

Matthew Jeffries Phones & Addresses

Bel Air, MD
Elkton, MD
Forest Hill, MD
2408 Lanside Dr, Wilmington, DE 19810 • 3024757710
Chadds Ford, PA
Aber Prov Grd, MD

Work

Position:

Financial Professional

Resumes

Matthew Jeffries

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Vice President At Alternative Investment Systems, Llc

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Position:

Vice President at Alternative Investment Systems, LLC

Location:

Baltimore, Maryland Area

Industry:

Financial Services

Work:

Alternative Investment Systems, LLC since Jan 2009
Vice President

Education:

University of Maryland Baltimore County 2005 - 2011
BS, Mechanical Engineering University of Maryland Baltimore County 2005 - 2011
MS, Systems Engineering

Matthew Jeffries

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Location:

United States

Us Patents

In Vitro System For Replication Of Rna-Dependent Rna Polymerase (Rdrp) Viruses
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US Patent:

20030175683, Sep 18, 2003
Filed:

Jan 31, 2002
Appl. No.:

10/066130
Inventors:

Robert King - West Chester PA, US
Matthew Jeffries - Indianapolis IN, US
Claudio Pasquinelli - Media PA, US
International Classification:

C12Q001/70
G01N033/53
G01N033/537
G01N033/543
C12N007/00
C12N007/01
C12N005/00
C12N005/02
C12P019/34
US Classification:

435/005000, 435/007100, 435/235100, 435/325000, 435/007940, 435/091100
Abstract:

An in vitro method to conduct genomic replication of the viral genomes of viruses that utilize RNA-dependent RNA polymerase for replication (RDRP viruses), such as HCV. The method employs a construct comprising the 3′ and 5′ untranslated regions (UTRs) of the viral genome which are operably linked on the 5′ and 3′ ends of a reporter sequence, in antisense orientation, such that when viral replication is occurring within the cell which produces RDRP, the reporter protein will be made. The method of the invention provides an efficient means for measuring genomic replication in RDRP viruses, and also for the rapid screening of compounds for their ability to inhibit genomic replication of RDRP viruses, including the virus (HCV).

In Vitro System For Replication Of Rna-Dependent Rna Polymerase (Rdrp) Viruses
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US Patent:

20040126388, Jul 1, 2004
Filed:

Dec 12, 2003
Appl. No.:

10/734801
Inventors:

Robert King - West Chester PA, US
Matthew Jeffries - Wilmington DE, US
Claudio Pasquinelli - Media PA, US
International Classification:

C12Q001/70
A61K039/29
US Classification:

424/189100, 435/005000
Abstract:

An in vitro method to conduct genomic replication of the viral genomes of viruses that utilize RNA-dependent RNA polymerase for replication (RDRP viruses), such as HCV. The method employs a construct comprising the 3′ and 5′ untranslated regions (UTRs) of the viral genome which are operably linked on the 5′ and 3′ ends of a reporter sequence, in antisense orientation, such that when viral replication is occurring within the cell which produces RDRP, the reporter protein will be made. The method of the invention provides an efficient means for measuring genomic replication in RDRP viruses, and also for the rapid screening of compounds for their ability to inhibit genomic replication of RDRP viruses, including the Hepatitis C virus (HCV).