Ulrike Bauer - Sandhausen, DE Zach Cheruvallath - San Diego CA, US Ulrich Deuschle - Bammental, DE Elena Dneprovskaia - San Diego CA, US Tim Gahman - Encinitas CA, US Kristina Giegrich - Lampertheim, DE Ronnie Hanecak - San Clemente CA, US Normand Hébert - Cardiff CA, US John Kiely - San Diego CA, US Ingo Kober - Gaiberg, DE Manfred Kögl - Eppelheim, DE Harald Kranz - Leimen, DE Claus Kremoser - Heidelberg, DE Matthew Lee - Solana Beach CA, US Kerstin Otte - Heidelberg, DE Carlton Sage - Cardiff CA, US Manish Sud - San Diego CA, US
Assignee:
Phenix Pharmaceuticals AG
International Classification:
A61K031/426 C07D277/20
US Classification:
514370, 548190, 548193, 548194
Abstract:
The present invention relates to compounds according to the general formula (I) which bind to the NR1H4 receptor and act as agonists of the NR1H4 receptor. The invention further relates to the treatment of diseases and/or conditions through binding of the nuclear receptor by the compounds and the production of medicaments using the compounds.
Ulrike Bauer - Sandhausen, DE Zach Cheruvallath - San Diego CA, US Ulrich Deuschle - Bammental, DE Elena Dneprovskaia - San Diego CA, US Tim Gahman - Encinitas CA, US Kristina Giegrich - Lampertheim, DE Ronnie Hanecak - San Clemente CA, US Normand Hébert - Cardiff CA, US John Kiely - San Diego CA, US Ingo Kober - Gaiberg, DE Manfred Kögl - Eppelheim, DE Harald Kranz - Leimen, DE Claus Kremoser - Heidelberg, DE Matthew Lee - Solana Beach CA, US Kerstin Otte - Heidelberg, DE Carlton Sage - Cardiff CA, US Manish Sud - San Diego CA, US
Assignee:
Phenex Pharmaceuticals AG
International Classification:
A61K 31/42 C07D 261/08
US Classification:
514378, 548247, 548248
Abstract:
The present invention relates to compounds according to the general formula (I) which bind to the nuclear receptor, NR1H4, and act as agonists and antagonists of the NR1H4 receptor. The invention further relates to the treatment of diseases and/or conditions through binding of the nuclear receptor by the compounds.
Ulrike Bauer - Sandhausen, DE Zach Cheruvallath - San Diego CA, US Ulrich Deuschle - Bammental, DE Elena Dneprovskaia - San Diego CA, US Tim Gahman - Encinitas CA, US Kristina Giegrich - Lampertheim, DE Ronnie Hanecak - San Clemente CA, US Normand Hébert - Cardiff CA, US John Kiely - San Diego CA, US Ingo Kober - Gaiberg, DE Manfred Kögl - Eppelheim, DE Harald Kranz - Leimen, DE Claus Kremoser - Heidelberg, DE Matthew Lee - Solana Beach CA, US Kerstin Otte - Heidelberg, DE Carlton Sage - Cardiff CA, US Manish Sud - San Diego CA, US
Assignee:
Phenex Pharmaceuticals AG - Ludwigshafen
International Classification:
C07D 239/42 A61K 31/505 A61K 31/506 A61P 35/00
US Classification:
544331, 544332, 514275
Abstract:
The invention provides compounds according to the general formula () which bind to the NRH receptor and act as agonists, antagonists or mixed agonists/antagonists of the NRH receptor. The invention further provides methods of treating diseases and/or conditions through binding of the nuclear receptor by the compounds and the production of medicaments using the compounds.
Ulrike Bauer - Sandhausen, DE Zach Cheruvallath - San Diego CA, US Ulrich Deuschle - Bammental, DE Elena Dneprovskaia - San Diego CA, US Tim Gahman - Encinitas CA, US Kristina Giegrich - Lampetheim, DE Ronnie Hanecak - San Clemente CA, US Normand Hebert - Cardiff CA, US John Kiely - San Diego CA, US Ingo Kober - Gaiberg, DE Manfred Kogl - Eppelheim, DE Harald Kranz - Leimen, DE Claus Kremoser - Heidelberg, DE Matthew Lee - Solana Beach CA, US Kerstin Otte - Heidelberg, DE Carlton Sage - Cardiff CA, US Manish Sud - San Diego CA, US
International Classification:
A61K 31/4436 A61K 31/44 C07D 409/04 C07D 213/72
US Classification:
514342000, 514352000, 546280400, 546304000
Abstract:
The present invention relates to compounds according to the general formula (1) which bind to the NR1H4 receptor and act as agonists, antagonists or mixed agonists/antagonists of the NR1H4 receptor. The invention further relates to the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and the production of medicaments using said compounds.
Rho Kinase Inhibitors And Compositions And Methods Of Use Thereof
- New York NY, US Matthew R. Lee - San Diego CA, US Celia Dominguez - Los Angeles CA, US Michael Barnes - Saffron Walden, GB Alan F. Haughan - Saffron Walden, GB Tammy Ladduwahetty - Saffron Walden, GB Christopher A. Luckhurst - Saffron Walden, GB Andrew J. Stott - Saffron Walden, GB Jason Tierney - Saffron Walden, GB
Provided herein are certain inhibitors of ROCK (rho-kinases or rho-associated kinases), which are useful as medicament, for the treatment Huntington's disease in particular.
- Shanghai, CN Michael Bruno PLEWE - San Diego CA, US Matthew Randolph LEE - Del Mar CA, US Xiaoran HAN - Shanghai, CN Liqun CHEN - Shanghai, CN Chengwei ZHANG - Shanghai, CN Jialiang WANG - Nashville TN, US
International Classification:
A61K 47/64 A61K 47/54
Abstract:
Provided herein are compounds, pharmaceutical compositions, and methods for binding or degrading target proteins. Further provided herein are compounds having a DNA damage-binding protein 1 (DDB1) binding moiety. Some such embodiments include a linker. Some such embodiments include a target protein binding moiety. Further provided herein are ligand-DDB1 complexes. Further provided herein are in vivo modified DDB1 proteins.
Heterocyclic Compounds And Imaging Agents For Imaging Huntingtin Protein
- New York NY, US Matthew Lee - San Diego CA, US Celia Dominguez - Los Angeles CA, US Peter David Johnson - Wantage, GB Catherine Jane Greenaway - Banbury, GB Kanika Khurana - London, GB Matthew Robert Mills - Wantage, GB Filippo Rota - Bristol, GB
Provided herein are certain compounds and imaging agents useful for detecting a disease or condition associated with protein aggregation, compositions thereof, and methods of their use.
Compounds And Probes For Imaging Huntingtin Protein
- New York NY, US Matthew Lee - San Diego CA, US Celia Dominguez - Los Angeles CA, US Peter David Johnson - Oxfordshire, GB Christopher John Brown - Abingdon, GB Sarah Hayes - Oxfordshire, GB Adrian Kotey - Didcot, GB Matthew Robert Mills - Wantage, GB Michael Edward Prime - Abingdon, GB
Provided herein are certain compounds and imaging agents useful for detecting a condition or disorder associated with protein aggregation, compositions thereof, and methods of their use.
Medicine Doctors
Dr. Matthew H Lee, Miami FL - MD (Doctor of Medicine)
Lee Rapp & Lee Mds 1900 W 4 St, Mount Vernon, IN 47620 8128384891 (phone), 8128383429 (fax)
Education:
Medical School University of Louisville School of Medicine Graduated: 1982
Procedures:
Cardiac Stress Test Allergen Immunotherapy Arthrocentesis Destruction of Benign/Premalignant Skin Lesions Skin Tags Removal Vaccine Administration
Conditions:
Acute Bronchitis Acute Sinusitis Anxiety Phobic Disorders Otitis Media Pneumonia
Languages:
English
Description:
Dr. Lee graduated from the University of Louisville School of Medicine in 1982. He works in Mount Vernon, IN and specializes in Family Medicine. Dr. Lee is affiliated with Deaconess Hospital.
Tallahassee Orthopedic Clinic 3334 Capital Medical Blvd STE 400, Tallahassee, FL 32308 8508778174 (phone), 8508775636 (fax)
Education:
Medical School Florida State University College of Medicine Graduated: 2006
Procedures:
Hip/Femur Fractures and Dislocations Spinal Cord Surgery Spinal Fusion Spinal Surgery Joint Arthroscopy Knee Arthroscopy Lower Arm/Elbow/Wrist Fractures and Dislocations Shoulder Surgery
Conditions:
Fractures, Dislocations, Derangement, and Sprains Internal Derangement of Knee Internal Derangement of Knee Cartilage Intervertebral Disc Degeneration Osteoarthritis
Languages:
English
Description:
Dr. Lee graduated from the Florida State University College of Medicine in 2006. He works in Tallahassee, FL and specializes in Orthopaedic Surgery. Dr. Lee is affiliated with Capital Regional Medical Center and Tallahassee Memorial Healthcare Hospital.
Wheaton Franciscan Medical GroupWheaton Franciscan Medical Group Obstetrics & Gynecology 3040 N 117 St STE 200, Milwaukee, WI 53222 4147780070 (phone), 4147780359 (fax)
Education:
Medical School Medical College of Georgia School of Medicine Graduated: 1995
Procedures:
Cesarean Section (C-Section) Hemorrhoid Procedures Hysterectomy Ovarian Surgery Skin Tags Removal Tubal Surgery Vaccine Administration Vaginal Delivery
Conditions:
Female Infertility Genital HPV Abnormal Vaginal Bleeding Breast Disorders Candidiasis of Vulva and Vagina
Languages:
Chinese English
Description:
Dr. Lee graduated from the Medical College of Georgia School of Medicine in 1995. He works in Wauwatosa, WI and specializes in Obstetrics & Gynecology. Dr. Lee is affiliated with Wheaton Franciscan Healthcare Saint Joseph Hospital.
University Pediatric Pulmonary 9 Richland Medical Park Dr STE 505, Columbia, SC 29203 8034342505 (phone), 8034342181 (fax)
Languages:
English Spanish
Description:
Mr. Lee works in Columbia, SC and specializes in Pediatric Pulmonology. Mr. Lee is affiliated with Palmetto Health Baptist and Palmetto Health Richland Hospital.
Caring ENT 103 N Garfield Ave STE G, Alhambra, CA 91801 6265761982 (phone), 6265760148 (fax)
Languages:
Chinese English
Description:
Dr. Lee works in Alhambra, CA and specializes in Otolaryngology. Dr. Lee is affiliated with Alhambra Hospital Medical Center, Garfield Medical Center and San Gabriel Valley Medical Center.
Jul 2011 to 2000 Account Executive/Digital Sports DirectorWireless Mike's Clinton, IL Mar 2010 to Jul 2011 Store ManagerBarbeck Communications Decatur, IL Jun 2008 to Mar 2010 Store ManagerUnited Parcel Service Springfield, IL Jun 2006 to Jun 2008 Manager
Education:
Ashworth College Norcross, GA 2009 Business ManagementLatham High School Warrensburg, IL 1998 to 2001 diploma
Jul 2011 to 2000 Account Executive/Digital Sports DirectorWireless Mike's Clinton, IL Mar 2010 to Jul 2011 Store ManagerBarbeck Communications Decatur, IL Jun 2008 to Mar 2010 Store ManagerUnited Parcel Service Springfield, IL Jun 2006 to Jun 2008 Manager
Education:
Ashworth College Norcross, GA 2009 Business ManagementLatham High School Warrensburg, IL 1998 to 2001 diploma
The Law Office of Matthew J. Lee, LLC 1401 Peachtree Street Ne, Suite 500, Atlanta, GA 30309 4048703558 (Office)
Licenses:
Georgia - Active Member in Good Standing 2004
Experience:
Attorney at The Law Office of Matthew J. Lee, LLC - 2012-present Senior Associate at Gonzalez Saggio & Harlan LLP - 2011 Associate at Adorno & Yoss, LLC - 2007-2011
Education:
Georgia State University College of Law Degree - JD - Juris Doctor - Law Graduated - 2004 Transylvania University Degree - BA - Bachelor of Arts - Economics Graduated - 1997
Specialties:
Debt Collection - 60%, years Bankruptcy / Debt - 25%, 19 years Litigation - 5%, years Debt Settlement - 5%, years Lawsuits / Disputes - 5%, years
Jeffery reported from Cairo, and Lidman from Jerusalem. Associated Press writers Matthew Lee in Tel Aviv, Israel; Josef Federman in Jerusalem; Najib Jobain in Rafah, Gaza Strip; and Kareem Chehayeb in Beirut contributed.
Date: Dec 01, 2023
Category: World
Source: Google
POLITICO Playbook: Dems flip 2022 on its head- POLITICO
DEAL OR NO DEAL As the world watches for negotiators to reach an agreement on a revived Iran nuclear deal, APs Matthew Lee and Aamer Madhani write that more movement could be on the way this week though a timeline for an official agreement is unclear. U.S. officials say they expect to respond
Date: Aug 24, 2022
Category: U.S.
Source: Google
Russian troops press on Kyiv; Ukraine's leader vows to fight
rake in Kyiv; Jill Lawless in London; Angela Charlton in Paris; Geir Moulson and Frank Jordans in Berlin; Raf Casert and Lorne Cook in Brussels; Vanessa Gera in Warsaw; Nic Dumitrache in Mariupol, Ukraine; Matt Sedensky in New York; Jennifer Peltz at the United Nations; and Robert Burns, Matthew Lee
Date: Feb 26, 2022
Category: Headlines
Source: Google
Russia invades Ukraine on many fronts in 'brutal act of war'
Francesca Ebel in Kyiv; Angela Charlton in Paris; Geir Moulson and Frank Jordans in Berlin; Raf Casert and Lorne Cook in Brussels; Nic Dumitrache in Mariupol, Ukraine, Inna Varennytsia in eastern Ukraine; and Robert Burns, Matthew Lee, Aamer Madhani, Eric Tucker, Nomaan Merchant, Ellen Knickmeyer,
Date: Feb 24, 2022
Category: Headlines
Source: Google
Jacksonville shooting suspect: A serious player in the high-pressure, big-money world of competitive gaming
"This is a competitive game," Matthew Lee, a Madden gamer who was scheduled to attend Sunday's event but did not end up making the trip, told The Washington Post late Sunday. "Everybody knows each other. When things get heated, they do get heated, everybody trash talks at events. But when the cards "People don't realize Madden is a growing game in terms of esports," gamer Matthew Lee told The Post. "There are guys who are going to make over $100,000 playing this year. With streaming and partnerships on top of the prize money you can win in tournaments, it's becoming a way to make a living."
Date: Aug 28, 2018
Category: Headlines
Source: Google
POLITICO Playbook PM: NEW: Dem super PAC hammers House GOP leadership in new ad
riday afternoon. SCOOP -- AP Sources: U.S. ends Syria stabilization funding, by Matthew Lee: U.S. officials said the administration notified Congress on Friday that it would not spend some $200 million that had been planned for Syria programs and would instead shift that money to other areas. The
Date: Aug 18, 2018
Category: Headlines
Source: Google
Cuba 'health attacks' a puzzle; embassy cuts permanent
Reach Josh Lederman on Twitter at http://twitter.com/joshledermanAP and Matthew Lee at http://twitter.com/APDiploWriter. Follow the AP's coverage of the Cuba mystery at http://apnews.com/tag/CubaHealthMystery .
mbat operations does not mean we have achieved the enduring defeat of I.S.I.S., Tillerson said at a meeting of anti-Islamic State group coalition members in Kuwait today, using an acronym for the group and warning that the coalition must keep focused on the threat. Matthew Lee reports at the AP.
Date: Feb 13, 2018
Category: World
Source: Google
Youtube
Tour Divide Matthew Lee 2009
Resupply in Silverthorne
Category:
People & Blogs
Uploaded:
24 Jun, 2009
Duration:
7m 11s
Matthew Lee - Great balls of fire - live in c...
Matthew Lee - great balls of fire Live in concert (Italy 2008) www.mat...
Category:
Music
Uploaded:
20 Feb, 2009
Duration:
2m 31s
Matthew Lee - Wild One live in concert
Matthew Lee live in Italy 2008 - Wild One www.matthewlee.i... www.mys...
Category:
Music
Uploaded:
18 Feb, 2009
Duration:
2m 26s
MATTHEW LEE - MEAN WOMAN BLUES- rock'n'roll p...
this is Matthew Lee live in concert see www.matthewlee.i... for more
Category:
Music
Uploaded:
27 Apr, 2007
Duration:
5m 22s
Matthew Lee live in concert - Great Balls Of ...
Matthew Lee sings GREAT BALLS OF FIRE www.matthewlee.i... for more
Category:
Music
Uploaded:
27 Apr, 2007
Duration:
2m 23s
Matthew Lee live "What'd I say/Whole lotta sh...
Matthew Lee live at JPII Jammin' Festival (guest) What'd I Say & Whole...
Tanaya Brown (1997-1997), Erin Mccormack (1996-2002), Matthew Lee (1986-1992), Kristen Moffatt (1988-1989)
Googleplus
Matthew Lee
Work:
Tianjin Foreign Studies University - English Teacher (2009) Cutco Knives - Sales Rep (2003-2003) Southwestern Books - Student Dealer (2004-2004) Wheaton College Speech Center and Admissions - Speech Coach (2006-2007) Walgreens - Assistant Manager (2006-2007) Streamline Financial Services - Business Manager (2007-2008) Life Time Fitness - Member Advisor (2008-2009) Simple Truths - Marketing Manager (2009-2011)
Education:
Wheaton College, Wheaton Warrenville South H.S.
Matthew Lee
Lived:
Tucker, GA
Atlanta, GA Marietta, GA Colorado Springs, CO Denver, CO Nashville, TN
About:
Matthew Russell Lee is a training specialist and eLearning developer. He is also an Inscape Publishing Certified DiSC® Facilitator who occasionally refers to himself in third person.
Matthew Lee
Work:
George's Aviation - Flight Instructor (2012) Moore Air - Flight Instructor (2010)
Education:
Hawaii Pacific University - Computer Science, Kamehameha Schools, Arline Transport Professionals - Piloting
Tagline:
I wish that I were flying my airplane.
Matthew Lee
Education:
Oklahoma State University–Stillwater - MS. Industrial Engineering, University of Missouri–Columbia - BSc. Statistics/Mathematics, University of Saskatchewan - BSc. Mathematics
About:
"It is his knowledge and use of the theory of probability that distinguishes the statistician from the expert in chemistry, agriculture, bacteriology, medicine, production, consumer research, eng...
Bragging Rights:
Canadian
Matthew Lee
Lived:
Longmont Groton, ct Tuscon, az San diego, ca Burlington, mass
Work:
Rebit INC - Tester
Education:
Front Range Community College
Matthew Lee
Work:
ESPN - Senior Editor, Blogs (2006) The Washington Post - Senior Producer, Sports (1997-2006)