Matthew F Mackey

age ~56

from Grantham, NH

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Also known as:

Matthew Faust Mackey
Matthew S Mackey
Mackey Matthew Faust
Matthew Y

Connected to:

Matthew Mackey Phones & Addresses

Grantham, NH
52 Henry Ave, Melrose, MA 02176
Brighton, MA
Morris Plains, NJ
Watertown, MA
Morristown, NJ
Bethesda, MD
West Lebanon, NH
Lakeland, FL
315 Allston St APT 2, Brighton, MA 02135

Work

Company:

Eisai
Jun 2007 to Nov 2012
Address:

Andover, MA
Position:

Senior research investigator & principal scientist

Education

Degree:

Ph.D.
School / High School:

Dartmouth Medical School
1992 to 1997
Specialities:

Immunology

Industries

Pharmaceuticals

Lawyers & Attorneys

Matthew Mackey - Lawyer

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ISLN:

922699948

Admitted:

2009

Resumes

Drug Discovery | Immunology | Autoimmunity | Inflammation | Immuno-Oncology | In Vivo Pharmacology | Biomarkers

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Location:

Greater Boston Area

Industry:

Pharmaceuticals

Work:

Eisai - Andover, MA Jun 2007 - Nov 2012
Senior Research Investigator & Principal Scientist
Sanofi - Bridgewater, NJ Jan 2002 - May 2007
Research Investigator & Senior Research Investigator
National Institutes of Health - Bethesda, MD Jun 1998 - Dec 2001
Post-doctoral Fellow

Education:

Dartmouth Medical School 1992 - 1997
Ph.D., Immunology Colby College 1988 - 1991
B.S., Major: biology, Minor: chemistry University of Vermont 1987 - 1988

Name / Title

Company / Classification

Phones & Addresses

Matthew Mackey
Controller

Vesey, Inc.
Computer Maintenance and Repair

35 Myrtle St A, Boston, MA 02114

Matthew Mackey
Chief Financial Officer, General Manager

Computer Geeks
Computer Maintenance/Repair

35 Myrtle St, Boston, MA 02114

Matthew A. Mackey

TIMBER TOP FIREWOOD, LLC

Us Patents

Tetrahydropyrazolopyrimidine Compounds
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US Patent:

20130324547, Dec 5, 2013
Filed:

May 31, 2013
Appl. No.:

13/907202
Inventors:

Roch Boivin - North Chelmsford MS, US
Eric Carlson - Merrimack NH, US
Atsushi Endo - Andover MA, US
Hans Hansen - Somerville MA, US
Lynn D. Hawkins - Concord MA, US
Sally Ishizaka - Weston MA, US
Matthew Mackey - Melrose MA, US
Sridhar Narayan - Belmont MA, US
Takashi Satoh - Andover MA, US
Shawn Schiller - Haverhill MA, US
International Classification:

C07D 471/04
US Classification:

51425216, 544281, 5142593
Abstract:

Embodiments of the disclosure relate to tetrahydropyrazolopyrimidine compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis

Methods Of Use
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US Patent:

20100305098, Dec 2, 2010
Filed:

Nov 13, 2008
Appl. No.:

12/739334
Inventors:

Qian Chen - Andover MA, US
Jesse Cheng-Lin Chow - Hooksett NH, US
Fabian Gusovsky - Andover MA, US
Marc Lamphier - North Andover MA, US
Matthew Faust Mackey - Melrose MA, US
Kenzo Muramoto - Ibaraki, JP
Shawn Schiller - Haverhill MA, US
Christine J. Shaffer - Litchfield NH, US
Mark Spyvee - Hampstead NH, US
International Classification:

A61K 31/55
A61P 37/06
A61P 19/02
US Classification:

51421202
Abstract:

A method of treating a disorder such as rheumatoid arthritis or multiple sclerosis in a subject is carried out by administering to the subject a composition comprising a modulator compound of Th1 differentiation or Th17 expansion.

Tetrahydropyrazolopyrimidine Compounds
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US Patent:

20200347050, Nov 5, 2020
Filed:

Apr 10, 2020
Appl. No.:

16/845594
Inventors:

- Tokyo, JP
Eric CARLSON - Merrimack NH, US
Atsushi ENDO - Andover MA, US
Hans HANSEN - Somerville MA, US
Lynn D. HAWKINS - Concord MA, US
Sally ISHIZAKA - Weston MA, US
Matthew MACKEY - Melrose MA, US
Sridhar NARAYAN - Belmont MA, US
Takashi SATOH - Andover MA, US
Shawn SCHILLER - Haverhill MA, US
Assignee:

Eisai R&D Management Co., Ltd. - Tokyo
International Classification:

C07D 471/04
C07D 487/04
A61K 31/519
A61K 31/55
Abstract:

Embodiments of the disclosure relate to tetrahydropyrazolopyrimidine compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis.

Selectively Substituted Quinoline Compounds
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US Patent:

20180354939, Dec 13, 2018
Filed:

Aug 22, 2018
Appl. No.:

16/108964
Inventors:

- Tokyo, JP
Hans Hansen - Somerville MA, US
Lynn Hawkins - Concord MA, US
Sally Ishizaka - Weston MA, US
Matthew Mackey - Melrose MA, US
Shawn Schiller - Haverhill MA, US
Chikako Ogawa - Basel, CH
Heather Davis - Haverhill MA, US
Atsushi Endo - Andover MA, US
Assignee:

EISAI R&D MANAGEMENT CO., LTD. - Tokyo
International Classification:

C07D 417/14
C07D 403/14
C07D 413/04
C07D 401/10
C07D 401/14
C07D 471/10
C07D 487/10
C07D 471/04
C07D 215/48
C12Q 1/6897
G01N 33/50
C07D 451/04
C07D 487/04
C07D 493/10
C07D 413/14
Abstract:

Embodiments of the disclosure relate to selectively substituted quinolone compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis.

Tetrahydropyrazolopyrimidine Compounds
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US Patent:

20180273532, Sep 27, 2018
Filed:

Dec 14, 2017
Appl. No.:

15/841767
Inventors:

- Tokyo, JP
Eric Carlson - Merrimack NH, US
Atsushi Endo - Andover MA, US
Hans Hansen - Somerville MA, US
Lynn D. Hawkins - Concord MA, US
Sally Ishizaka - Weston MA, US
Matthew Mackey - Melrose MA, US
Sridhar Narayan - Belmont MA, US
Takashi Satoh - Andover MA, US
Shawn Schiller - Haverhill MA, US
Assignee:

EISAI R&D MANAGEMENT CO., LTD. - TOKYO
International Classification:

C07D 471/04
A61K 31/55
C07D 487/04
A61K 31/519
Abstract:

Embodiments of the disclosure relate to tetrahydropyrazolopyrimidine compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis.

Selectively Substituted Quinoline Compounds
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US Patent:

20180030045, Feb 1, 2018
Filed:

Aug 7, 2017
Appl. No.:

15/670904
Inventors:

- Tokyo, JP
Hans HANSEN - Somerville MA, US
Lynn HAWKINS - Concord MA, US
Sally ISHIZAKA - Weston MA, US
Matthew MACKEY - Melrose MA, US
Shawn SCHILLER - Haverhill MA, US
Chikako OGAWA - Basel, CH
Heather DAVIS - Haverhill MA, US
Atsushi ENDO - Andover MA, US
Assignee:

EISAI R&D MANAGEMENT CO., LTD. - Tokyo
International Classification:

C07D 417/14
C07D 413/04
C07D 401/10
C07D 401/14
C07D 471/10
C07D 487/10
C07D 471/04
C07D 215/48
C12Q 1/68
G01N 33/50
C07D 451/04
C07D 487/04
C07D 493/10
C07D 413/14
C07D 403/14
Abstract:

Embodiments of the disclosure relate to selectively substituted quinoline compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis.

Tetrahydropyrazolopyrimidine Compounds
view source
US Patent:

20160339032, Nov 24, 2016
Filed:

Aug 10, 2016
Appl. No.:

15/233520
Inventors:

- Tokyo, JP
Eric Carlson - Merrimack NH, US
Atsushi Endo - Andover MA, US
Hans Hansen - Somerville MA, US
Lynn D. Hawkins - Concord MA, US
Sally Ishizaka - Weston MA, US
Matthew Mackey - Melrose MA, US
Sridhar Narayan - Belmont MA, US
Takashi Satoh - Andover MA, US
Shawn Schiller - Haverhill MA, US
International Classification:

A61K 31/519
A61K 31/55
Abstract:

Embodiments of the disclosure relate to tetrahydropyrazolopyrimidine compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis

Selectively Substituted Quinoline Compounds
view source
US Patent:

20160326161, Nov 10, 2016
Filed:

Jul 27, 2016
Appl. No.:

15/220949
Inventors:

- Tokyo, JP
Hans HANSEN - Somerville MA, US
Lynn HAWKINS - Concord MA, US
Sally ISHIZAKA - Weston MA, US
Matthew MACKEY - Melrose MA, US
Shawn SCHILLER - Haverhill MA, US
Chikako OGAWA - Basel, CH
Heather DAVIS - Haverhill MA, US
Atsushi ENDO - Andover MA, US
Assignee:

EISAI R&D MANAGEMENT CO., LTD. - Tokyo
International Classification:

C07D 417/14
C07D 413/04
C07D 471/10
C12Q 1/68
C07D 493/10
C07D 487/04
C07D 451/04
G01N 33/50
C07D 413/14
C07D 487/10
Abstract:

Embodiments of the disclosure relate to selectively substituted quinoline compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis.