Matthew F Sammons

US Patent:

20130296351, Nov 7, 2013

Filed:

May 2, 2013

Appl. No.:

13/875604

Inventors:

Pfizer Inc. - , US
Edward L. Conn - Griswold CT, US
Robert L. Dow - Groton CT, US
Matthew S. Dowling - Groton CT, US
David Hepworth - Concord MA, US
Daniel Wei-Shung Kung - Salem CT, US
Suvi Orr - Old Saybrook CT, US
Benjamin N. Rocke - Manchester CT, US
Roger B. Ruggeri - Cambridge MA, US
Matthew F. Sammons - Quincy MA, US
Joseph S. Warmus - Ledyard CT, US
Yan Zhang - Falmouth ME, US

International Classification:

C07D 239/56
A61K 45/06
A61K 31/513

US Classification:

514274, 544312

Abstract:

Myeloperoxidase inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to treat, for example, cardiovascular conditions.

US Patent:

20130123230, May 16, 2013

Filed:

Nov 7, 2012

Appl. No.:

13/670852

Inventors:

Philip A. Carpino - Newton MA, US
Edward L. Conn - Griswold CT, US
Robert L. Dow - Groton CT, US
Matthew S. Dowling - Groton CT, US
David Hepworth - Concord MA, US
Daniel Wei-Shung Kung - Salem CT, US
Suvi Orr - Old Saybrook CT, US
Benjamin N. Rocke - Manchester CT, US
Roger B. Ruggeri - Cambridge MA, US
Matthew F. Sammons - Quincy MA, US
Joseph S. Warmus - Ledyard CT, US
Yan Zhang - Falmouth ME, US

International Classification:

C07D 239/56
C07D 401/04
C07D 405/10
C07D 403/10
C07D 487/04
C07D 409/10
C07D 417/10
C07D 401/06
C07D 403/06
C07D 413/06
A61K 31/5377
C07D 405/04
C07D 403/04
C07D 409/04
C07D 401/10
C07D 403/12
A61K 31/352
A61K 45/06
A61K 31/513

US Classification:

5142102, 544312, 514274, 544310, 544314, 544296, 544123, 5142358, 51425505, 544295, 51425214

Abstract:

Myeloperoxidase inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to treat, for example, cardiovascular conditions.

US Patent:

20220257563, Aug 18, 2022

Filed:

Apr 22, 2022

Appl. No.:

17/660270

Inventors:

- New York NY, US
Matthew Richard Reese - Mystic CT, US
Matthew Forrest Sammons - Quincy MA, US
Jamison Bryce Tuttle - Marblehead MA, US
Patrick Robert Verhoest - Newton MA, US
Qingyi Yang - Lexington MA, US

Assignee:

Pfizer Inc. - New York NY

International Classification:

A61K 31/403
A61P 31/14
C07D 403/12
A61K 31/427
A61K 31/401

Abstract:

The invention relates to compounds of Formula I″wherein R, R, R, R, p, q and q′ are as defined herein, pharmaceutical compositions comprising the compounds, methods of treating coronavirus infection such as COVID-19 in a patient by administering therapeutically effective amounts of the compounds, and methods of inhibiting or preventing replication of coronaviruses such as SARS-CoV-2 with the compounds.

US Patent:

20230105838, Apr 6, 2023

Filed:

Apr 1, 2021

Appl. No.:

17/906109

Inventors:

- New York NY, US
Robert Steven Kania - Del Mar CA, US
Dafydd Rhys Owen - Concord MA, US
Martin Youngjin Pettersson - Littleton MA, US
Matthew Forrest Sammons - Quincy MA, US
Jamison Bryce Tuttle - Marblehead MA, US

Assignee:

Pfizer Inc. - New York NY

International Classification:

A61K 38/00
A61K 31/167
A61K 31/405
A61K 31/513
A61K 31/519
A61K 31/573
A61K 31/609
A61K 31/706
A61P 31/14

Abstract:

The invention relates to methods of treating COVID-19 in a patient by administering therapeutically effective amounts of certain SARS-CoV-2 inhibitor compounds or pharmaceutical compositions containing them to a patient in need thereof. The invention also relates to inhibiting SARS-CoV-2 coronavirus viral replication activity comprising contacting SARS-CoV-2-related coronavirus protease with a therapeutically effective amount of a SARS-Cov-2 protease inhibitor, such as a SARS-Cov-2 3CL protease inhibitor and compositions comprising the same.

US Patent:

20230019853, Jan 19, 2023

Filed:

Jun 8, 2021

Appl. No.:

17/341877

Inventors:

- New York NY, US
Michelle Renee Garnsey - Medford MA, US
Kevin Alexander Ogilvie - Gales Ferry CT, US
Jana Polivkova - Mystic CT, US
Matthew Forrest Sammons - Quincy MA, US
Aaron Christopher Smith - North Providence RI, US
Qingyi Yang - Lexington MA, US

Assignee:

Pfizer Inc. - New York NY

International Classification:

C07D 471/20
C07D 519/00

Abstract:

Described herein are compounds of Formula I:and their pharmaceutically acceptable salts, wherein R, R, R, X, Y, Y, Y, Yand Yare defined herein; their use as MC4R antagonists; pharmaceutical compositions containing such compounds and salts; the use of such compounds and salts to treat, for example, cachexia, anorexia, or anorexia nervosa; and intermediates and processes for preparing such compounds and salts.

US Patent:

20200331909, Oct 22, 2020

Filed:

Apr 15, 2020

Appl. No.:

16/849329

Inventors:

- New York NY, US
Douglas Carl Behenna - San Juan Capistrano CA, US
Kimberly O. Cameron - Cambridge MA, US
Ping Chen - San Diego CA, US
John M. Curto - Mystic CT, US
Kevin Daniel Freeman-Cook - Carlsbad CA, US
Mehran Jalaie - San Diego CA, US
Robert Steven Kania - Del Mar CA, US
Yajing Lian - Waterford CT, US
Sajiv Krishnan Nair - San Diego CA, US
Cynthia Louise Palmer - La Mesa CA, US
Martin Youngjin Pettersson - Littleton MA, US
Eugene Yuanjin Rui - San Diego CA, US
Matthew Sammons - Quincy MA, US
Qingyi Yang - Lexington MA, US
Liying Zhang - Lexington MA, US

Assignee:

Pfizer Inc. - New York NY

International Classification:

C07D 471/04
A61P 9/12

Abstract:

This invention relates to compounds of general Formula Iin which A, R, R, Rand Rare as defined herein, and the pharmaceutically acceptable salts thereof; to pharmaceutical compositions comprising such compounds and salts; to methods of using such compounds, salts and compositions for treating pulmonary hypertension and related diseases, like pulmonary arterial hypertension; to methods of using such compounds, salts and compositions for treating abnormal cell growth, such as cancer; and to processes to make such compounds, salts and compositions.

US Patent:

20160304469, Oct 20, 2016

Filed:

Jun 24, 2016

Appl. No.:

15/191943

Inventors:

- New York NY, US
Edward L. Conn - Griswold CT, US
Robert L. Dow - Groton CT, US
Matthew S. Dowling - Old Lyme CT, US
David Hepworth - Concord MA, US
Daniel Wei-Shung Kung - Salem CT, US
Suvi Orr - San Diego CA, US
Benjamin N. Rocke - Manchester CT, US
Roger B. Ruggeri - Waterford CT, US
Matthew F. Sammons - Quincy MA, US
Joseph S. Warmus - Ledyard CT, US
Yan Zhang - Falmouth ME, US

Assignee:

Pfizer Inc. - New York NY

International Classification:

C07D 239/56
A61K 45/06
C07D 401/04
C07D 405/04
C07D 403/04
C07D 471/04
C07D 409/04
C07D 417/04
C07D 405/10
C07D 405/06
C07D 403/06
C07D 403/10
C07D 401/06
C07D 413/06
A61K 31/5377
C07D 403/12
A61K 31/513

Abstract:

Myeloperoxidase inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to treat, for example, cardiovascular conditions.

US Patent:

20140288049, Sep 25, 2014

Filed:

Jun 9, 2014

Appl. No.:

14/299497

Inventors:

- New York NY, US
Edward L. Conn - Griswold CT, US
Robert L. Dow - Groton CT, US
Matthew S. Dowling - Groton CT, US
David Hepworth - Concord MA, US
Daniel Wei-Shung Kung - Salem CT, US
Suvi Orr - Old Saybrook CT, US
Benjamin N. Rocke - Manchester CT, US
Roger B. Ruggeri - Cambridge MA, US
Matthew F. Sammons - Quincy MA, US
Joseph S. Warmus - Ledyard CT, US
Yan Zhang - Falmouth ME, US

International Classification:

C07D 239/56
C07D 401/04
C07D 405/04
C07D 403/04
C07D 471/04
A61K 31/5377
C07D 417/04
C07D 403/06
C07D 403/10
C07D 401/06
C07D 413/06
A61K 31/513
C07D 409/04

US Classification:

51421018, 544312, 514274, 544314, 544310, 544296, 544123, 5142358, 544295, 51425505, 5142102, 51425214

Abstract:

Myeloperoxidase inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to treat, for example, cardiovascular conditions.