Maxine Y Allen

US Patent:

6383792, May 7, 2002

Filed:

Dec 3, 1999

Appl. No.:

09/454818

Inventors:

Maxine J. Allen - Encinitas CA
Marc Rutter - San Diego CA
Alan J. Buckler - Cardiff CA

Assignee:

AxyS Pharmaceuticals, Inc. - South San Francisco CA

International Classification:

C12N 914

US Classification:

435195, 530350

Abstract:

The invention features polynucleotides encoding novel GTP-binding polypeptides, hereinafter referred to as RAQ polypeptides; expression vectors comprising a RAQ polynucleotide of the invention; isolated cells comprising a RAQ-encoding vector; a transgenic non-human animal comprising an alteration in a RAQ gene; and the use of RAQ polynucleotides in detecting in an individual the presence of a genetic polymorphism of a RAQ gene. The invention further features novel RAQ polypeptides; monoclonal antibodies specific for RAQ polypeptides; and a method for making RAQ polypeptides.

US Patent:

60177101, Jan 25, 2000

Filed:

May 13, 1998

Appl. No.:

9/078317

Inventors:

Maxine J. Allen - Encinitas CA
Marc Rutter - San Diego CA
Alan J. Buckler - Cardiff CA

Assignee:

AxyS Pharmaceuticals, Inc. - South San Francisco CA

International Classification:

C12Q 168
C12Q 2106
C12N 1500
C12N 500
C07H 2102

US Classification:

435 6

Abstract:

The invention features polynucleotides encoding novel GTP-binding polypeptides, hereinafter referred to as RAQ polypeptides; expression vectors comprising a RAQ polynucleotide of the invention; isolated cells comprising a RAQ-encoding vector; a transgenic non-human animal comprising an alteration in a RAQ gene; and the use of RAQ polynucleotides in detecting in an individual the presence of a genetic polymorphism of a RAQ gene. The invention further features novel RAQ polypeptides; monoclonal antibodies specific for RAQ polypeptides; and a method for making RAQ polypeptides.