Robert Ray - Stuart FL, US May Lui - Sebastian FL, US Susan Summers - Stuart FL, US Brian Smith - Port St. Lucie FL, US
Assignee:
FlexSite Diagnostics, Inc. - Palm City FL
International Classification:
G01N021/00
US Classification:
422/056000
Abstract:
A device for collecting, drying, and transporting a urine sample, and extracting an analyte of interest from the dried sample for determining the presence or absence of the analyte or, if present, the amount or concentration thereof, is described. A preferred embodiment of the device is a sample collection strip which includes a collection pad for collecting and retaining the sample and a handle member for handling or manipulation of the device. Methods of use, and kits relating to the device are also described.
Tatsuo Higa - Naha, JP Ryuichi Sakai - Vero Beach FL Shigeo Kohmoto - Vero Beach FL May S. Lui - Sebastian FL
Assignee:
Harbor Branch Oceanographic Institution, Inc. - Ft. Pierce FL
International Classification:
A61K 31475 C07D51900 C07D47104
US Classification:
514281
Abstract:
This invention relates to antitumor alkaloid compositions, a process of producing the compositions and a method for inhibiting tumors utilizing the compositions. More particularly, the compositions are antitumor alkaloids which are derived from marine organisms, i. e. , the marine sponge Amphimedon sp.
Tatsuo Higa - Naha, JP Ryuichi Sakai - Vero Beach FL May S. Lui - Sebastian FL
Assignee:
Harbor Branch Oceanographic Institution, Inc. - Ft. Pierce FL
International Classification:
C07D32300
US Classification:
549267
Abstract:
This invention relates to novel macrolide compositions which are useful as antitumor, antiviral and antifungal compositions, a process of producing the compositions and a method for inhibiting tumors, viruses and fungi utilizing the compositions. More particularly, the novel macrolide compositions are organic misakinolide and misakinolide derivative compositions which are derived from marine sponges genus Theonella.
Topsentin Compounds Effective Against Viruses And Certain Tumors
Sarath P. Gunasekera - Vero Beach FL Sue S. Cross - Ft. Pierce FL Yoel Kashman - Tel Aviv, IL May S. Lui - Sebastian FL Kenneth L. Rinehart - Urbana IL Shinji Tsujii - Okayama, JP
Assignee:
Harbor Branch Oceanographic Institution, Inc. - Ft. Pierce FL
International Classification:
A61K 31415 C07D40314
US Classification:
514397
Abstract:
A new class of novel, biologically active bisindole alkaloid compounds, which have been named topsentins, pharmaceutical compositions containing them, methods of producing the compounds and methods of using them are disclosed. This new class of compounds has the generic formula: ##STR1## R. sup. 1-8 are the same or different selected from --H, --OH, halogen, --R, --OR, --OCOR, or --OA; Y is the single group --O, or two groups, same or different, selected from --H, --OH, --OR, or --OCOR with the provision that Y shall not be two --OH groups; Z are the same or different selected from --H, --R; R is C1-5 alkyl and A is --R--phenyl. The compounds are antiviral agents and antitumor agents which are effective against specific tumors.
Novel Polyacetylene Compositions And Their Methods Of Use
Amy E. Wright - Ft. Pierce FL Winnie C. Thompson - Vero Beach FL May S. Lui - Vero Beach FL
Assignee:
Harbor Branch Oceanographic Institution, Inc. - Fort Pierce FL
International Classification:
C07C 33044 A61K 31045 A61K 3112 A61K 3122
US Classification:
514675
Abstract:
This invention relates to novel polyacetylene compositions, a process of producing the compositions and a method for inhibiting tumors utilizing the compositions. More particularly, the compositions are antitumor polyacetylenes which are derived form marine organisms, i. e. , the marine sponge Cribrochalina dura.