Mei Chai Chen

US Patent:

6925685, Aug 9, 2005

Filed:

Sep 8, 2003

Appl. No.:

10/658153

Inventors:

Mei Li Chen - Arcadia CA, US

International Classification:

E05D011/10
E05D007/06

US Classification:

16332, 16252, 16239, 16241, 16382, 49388

Abstract:

A pivot hinge for pivotally mounting a glass structure to a border frame, includes a joint body having two joint walls for securely sandwiching the glass structure, a joint hub including a supporting shaft having an adjusting portion, and an angular adjustment arrangement including a joint seat, having an adjustment sleeve, adapted for securely mounting to the border frame, wherein the adjusting portion of the supporting shaft is rotatably inserted into the adjustment sleeve in such a manner that the joint body is adapted to angularly move with respect to the joint seat for adjustably aligning the glass structure with the border frame and an angular adjustment locker securely lock up the supporting shaft within the adjustment sleeve in a rotatably movable manner for retaining an alignment of the glass structure in position with the border frame so as to pivotally mount the glass structure to the border frame.

US Patent:

7010832, Mar 14, 2006

Filed:

Oct 2, 2003

Appl. No.:

10/678147

Inventors:

Mei Li Chen - Arcadia CA, US

International Classification:

E05D 5/02

US Classification:

16252, 16235, 16240, 16332

Abstract:

A side pivot hinge includes a joint body for securely mounting a side edge portion of the glass structure, a joint seat, having a joint sleeve, for securely mounting to a border frame, and an angular adjustment arrangement which includes a joint housing securely mounted to the joint body, a supporting shaft rotatably supported by the joint housing to rotatably insert into the joint sleeve to pivotally connect the joint body with the joint seat, and an angular adjustment locker to securely lock up the supporting shaft within the joint housing such that when the joint body is angularly moved with the joint seat for adjustably aligning the glass structure with the border frame, the supporting shaft is locked up at the joint housing in a rotatably movable manner via the angular adjustment locker for retaining an alignment of the glass structure in position with the border frame.

US Patent:

8022037, Sep 20, 2011

Filed:

Jan 8, 2008

Appl. No.:

12/522446

Inventors:

Wei Li - Altadena CA, US
Mei Chen - Altadena CA, US
David T. Woodley - Altadena CA, US

Assignee:

University of Southern California - Los Angeles CA

International Classification:

A61K 38/00
A61K 45/00

US Classification:

514 165, 424 852

Abstract:

A wound healing composition comprising an amount of heat shock protein effective to promote wound healing and a method thereof to apply the composition. A preferred heat shock protein is either full-length hsp90α or the middle domain plus the charged sequence of hsp90α. The composition is topically applied to skin wounds, covering the outer surface of the wound. The heat shock protein acts by promoting migration of both human epidermal keratinocyte and dermal fibroblasts to the wound in order to close, heal, and remodel the wound.

US Patent:

8410055, Apr 2, 2013

Filed:

Aug 15, 2011

Appl. No.:

13/210200

Inventors:

Wei Li - Altadena CA, US
Mei Chen - Altadena CA, US
David T. Woodley - Altadena CA, US

Assignee:

University of Southern California - Los Angeles CA

International Classification:

A61K 38/00
A61K 45/00
A61P 43/00

US Classification:

514 186, 514 165, 424 852

Abstract:

A wound healing composition comprising an amount of heat shock protein effective to promote wound healing and a method thereof to apply the composition. A preferred heat shock protein is either full-length hsp90α or the middle domain plus the charged sequence of hsp90α. The composition is topically applied to skin wounds, covering the outer surface of the wound. The heat shock protein acts by promoting migration of both human epidermal keratinocyte and dermal fibroblasts to the wound in order to close, heal, and remodel the wound.

US Patent:

8455443, Jun 4, 2013

Filed:

May 30, 2012

Appl. No.:

13/484162

Inventors:

Wei Li - Altadena CA, US
Mei Chen - Altadena CA, US
David T. Woodley - Altadena CA, US
Chieh-Fang Cheng - Alhambra CA, US

Assignee:

University of Southern California - Los Angeles CA

International Classification:

A61K 38/00
A61K 45/00

US Classification:

514 165, 424 852

Abstract:

A wound healing composition comprising a class of polypeptide compounds having a polypeptide chain with 5 to 120 amino acid units per chain. The composition includes a pharmaceutical medium to carry the polypeptide compound, such as an aqueous solution, suspension, dispersion, salve, ointment, gel, cream, lotion, spray or paste. Additionally, a method of applying a wound healing composition comprising a class of polypeptide compounds having a polypeptide chain with 5 to 120 amino acid units per chain in a concentration of from about 1 μg/ml to about 100 μg/ml for a time sufficient to heal the wound is disclosed.

US Patent:

8207118, Jun 26, 2012

Filed:

Jul 17, 2009

Appl. No.:

12/505361

Inventors:

Wei Li - Altadena CA, US
Mei Chen - Altadena CA, US
David T. Woodley - Altadena CA, US
Chieh-Fang Cheng - Alhambra CA, US

Assignee:

University of Southern California - Los Angeles CA

International Classification:

A61K 38/00
A61K 45/00

US Classification:

514 165, 424 852

Abstract:

A wound healing composition comprising a class of polypeptide compounds having a polypeptide chain with 5 to 120 amino acid units per chain. The composition includes a pharmaceutical medium to carry the polypeptide compound, such as an aqueous solution, suspension, dispersion, salve, ointment, gel, cream, lotion, spray or paste. Additionally, a method of applying a wound healing composition comprising a class of polypeptide compounds having a polypeptide chain with 5 to 120 amino acid units per chain in a concentration of from about 1 μg/ml to about 100 μg/ml for a time sufficient to heal the wound is disclosed.

US Patent:

20050103420, May 19, 2005

Filed:

Nov 14, 2003

Appl. No.:

10/706916

Inventors:

Mei Chen - San Marino CA, US

International Classification:

B32B031/00

US Classification:

156057000

Abstract:

A attachment method for pressed flowers which includes the steps of: covering pressed flowers with a layer of transparent resin which becomes sticky when heated, attaching said pressed flowers to a surface of a base material, and indirectly heating said pressed flowers to make said resin become sticky thereby firmly adhering said pressed flowers to said base material without the use of adhesive and therefore making it easier and more convenient for decoration. It is also very convenient to separate the flower from the base material and heat it indirectly again to attach to another base material. The resin coating the flowers has the additional benefits of preventing the pressed flowers from color fading, wear and tear, and extending their usage.

US Patent:

20100172886, Jul 8, 2010

Filed:

Nov 28, 2007

Appl. No.:

12/516276

Inventors:

Mei Chen - Altadena CA, US
David Woodley - Altadena CA, US

Assignee:

UNIVERSITY OF SOUTHERN CALIFORNIA - Los Angeles CA

International Classification:

A61K 35/12
A61K 38/17
A61P 17/02

US Classification:

424 9321, 514 12

Abstract:

The present invention discloses a method for treating wounds and for accelerating the healing of wounds by administering an effective amount of a pharmaceutical composition containing type VII collagen protein, mini-C7 protein, variants thereof or any combinations thereof. The pharmaceutical composition may be administered through a variety of routes including intravenous injection, topical application, or oral ingestion. The method may further include administering a genetically modified fibroblast capable of expressing type VII collagen protein, mini-C7 protein, variants thereof or small growth factors to achieve synergistic healing effect.