Jiacheng Zhou - Newark DE, US Pingli Liu - Newark DE, US Qiyan Lin - Newark DE, US Brian W. Metcalf - Moraga CA, US David Meloni - Bear DE, US Yongchun Pan - Newark DE, US Michael Xia - Wilmington DE, US Mei Li - Newark DE, US Tai-Yuen Yue - Hockessin DE, US James D. Rodgers - Landenberg PA, US Haisheng Wang - Hockessin DE, US
Assignee:
Incyte Corporation - Wilmington DE
International Classification:
C07D 487/00
US Classification:
544280
Abstract:
The present invention is related to processes for preparing chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines of Formula III, and related synthetic intermediate compounds. The chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines are useful as inhibitors of the Janus Kinase family of protein tyrosine kinases (JAKs) for treatment of inflammatory diseases, myeloproliferative disorders, and other diseases.
Hydroxyl, Keto, And Glucuronide Derivatives Of 3-(4-(7H-Pyrrolo[2,3-D] Pyrimidin-4-Yl)-1H-Pyrazol-1-Yl)-3-Cyclopentylpropanenitrile
James D. Rodgers - Landenberg PA, US Adam Shilling - Wilmington DE, US Argyrios G. Arvanitis - Kennett Square PA, US Stacey Shepard - Wilmington DE, US Laurine G. Galya - Wilmington DE, US Mei Li - Wilmington DE, US Frank M. Nedza - Wilmington DE, US
The present invention provides hydroxyl, keto, and glucuronide derivatives of 3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile.
Hydroxyl, Keto, And Glucuronide Derivatives Of 3-(4-(7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)-1H-Pyrazol-1-Yl)-3-Cyclopentylpropanenitrile
James D. Rodgers - Landenberg PA, US Adam Shilling - Wilmington DE, US Argyrios G. Arvanitis - Kennett Square PA, US Stacey Shepard - Wilmington DE, US Laurine G. Galya - Wilmington DE, US Mei Li - Wilmington DE, US Frank M. Nedza - Wilmington DE, US
Assignee:
INCYTE CORPORATION - Wilmington DE
International Classification:
C07H 17/02
US Classification:
514 27, 536 174
Abstract:
The present invention provides hydroxyl, keto, and glucuronide derivatives of 3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile.
Processes For Preparing Jak Inhibitors And Related Intermediate Compounds
- Wilmington DE, US Qiyan Lin - Newark DE, US Brian W. Metcalf - Moraga CA, US David Meloni - Bear DE, US Yongchun Pan - Newark DE, US Michael Xia - Wilmington DE, US Mei Li - Newark DE, US Tai-Yuen Yue - Hockessin DE, US James D. Rodgers - Landenberg PA, US Haisheng Wang - Hockessin DE, US
The present invention is related to processes for preparing chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines of Formula III, and related synthetic intermediate compounds. The chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines are useful as inhibitors of the Janus Kinase family of protein tyrosine kinases (JAKs) for treatment of inflammatory diseases, myeloproliferative disorders, and other diseases.
- Wilmington DE, US Ying Liu - Exton PA, US Mei Li - Newark DE, US Tanvi Shah - Philadelphia PA, US Huifang Wu - West Chester PA, US
International Classification:
A61K 31/445 A61K 9/00 A61K 9/20 A61K 9/48
Abstract:
The present application relates to pharmaceutical formulations and dosage forms of a lysine specific demethylase-1 (LSD1) inhibitor, or a pharmaceutically acceptable salt, solvate, or hydrate thereof, including methods of preparation thereof, which are useful in the treatment of LSD1 mediated diseases such as cancer.
- Wilmington DE, US Ying Liu - Exton PA, US Mei Li - Newark DE, US Tanvi Shah - Philadelphia PA, US Huifang Wu - West Chester PA, US
International Classification:
A61K 31/445 A61K 9/20 A61K 9/00 A61K 9/48
Abstract:
The present application relates to pharmaceutical formulations and dosage forms of a lysine specific demethylase-1 (LSD1) inhibitor, or a pharmaceutically acceptable salt, solvate, or hydrate thereof, including methods of preparation thereof, which are useful in the treatment of LSD1 mediated diseases such as cancer.
The present application relates to pharmaceutical formulations and dosage forms of a lysine specific demethylase-1 (LSD1) inhibitor, or a pharmaceutically acceptable salt, solvate, or hydrate thereof, including methods of preparation thereof, which are useful in the treatment of LSD1 mediated diseases such as cancer.
Hydroxyl, Keto, And Glucuronide Derivatives Of 3-(4-(7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)-1H-Pyrazol-1-Yl)-3-Cyclopentylpropanenitrile
- Wilmington DE, US Adam Shilling - Wilmington DE, US Argyrios G. Arvanitis - Kennett Square PA, US Stacey Shepard - Wilmington DE, US Laurine G. Galya - Wilmington DE, US Mei Li - Wilmington DE, US Frank M. Nedza - Wilmington DE, US
International Classification:
C07H 17/02 C07D 487/04
US Classification:
514 27, 5142651
Abstract:
The present invention provides hydroxyl, keto, and glucuronide derivatives of 3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile.
Name / Title
Company / Classification
Phones & Addresses
Mei Z Li Owner
Winzone Realty Inc Real Estate
14120 Holly Ave, Flushing, NY 11355
Mei Li Chief Executive
Winzone Realty Inc Real Estate
14120 Holly Ave, Flushing, NY 11355
Mei Zhen Li
Exit Kingdom Realty Real Estate Agents and Managers
6856 Groton St, Flushing, NY 11375
Mei Li Owner
Mei Li Cosmetic Ret Misc Merchandise
116 N Franklin Tpke, Darlington, NJ 07446 2013278887
Mei Xiu Li Director
Liao's Garden, Inc Restaurant
Lincoln, AL 35096 New York, NY 10038
Mei F. Li Principal
LITTLES, INC Business Services at Non-Commercial Site
134-39 Blossom Ave APT 6-G, Flushing, NY 11355 13439 Blossom Ave, Flushing, NY 11355
Mei H. Li Partner, Internal Medicine, Medical Doctor
Xiang LI MD Medical Doctor's Office · Internist
98 James St #201, Edison, NJ 08820 7329069882
Mei Yun Li Chairman of the Board
GIMEI REALTY CORP Real Estate Agent/Manager
63 Ave A #15G, New York, NY 10009 63 Ave A / #15G, New York, NY 10009
Mar 2012 to Present ACH OPERATIONS SPECIALISTDeutsche Bank Jersey City, NJ May 2009 to Feb 2010 Assets transfer SpecialistDEUTSCHE BANK Jersey City, NJ Sep 2005 to May 2009 Mutual Fund Operations AssociateDEUTSCHE BANK Jersey City, NJ Jul 2004 to Sep 2005 Operations SpecialistTHE UFJ BANK New York, NY Nov 2001 to Mar 2003 Internal InspectorTHE UFJ BANK New York, NY Mar 2000 to Nov 2001 Accounts Payable Clerk
Education:
State University of Old Westbury College Westbury, NY Sep 1996 to May 2000 Bachelor of Science in Finance