Mi X Chen from Orlando, FL, age 59

Resumes

Mi Chen

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Mi Chen

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Mi Chen

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Wikipedia References

Mi Gao Huang Chen

About:

Died:

2005

Work:

Position:

Judge

Education:

Area of science:

Housing • Criminal justice

Specialty:

Director

Skills & Activities:

Preference:

Violent disorder • Harassment • Violence • Guilty • Hate crime • Abuse • Affray

Us Patents

Coumarin Derivatives Useful As Tnfα Inhibitors
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US Patent:

7026491, Apr 11, 2006
Filed:

Jul 19, 2001
Appl. No.:

10/333366
Inventors:

Jie Fei Cheng - Carlsbad CA, US
Hirotaka Kashiwagi - Shizuoka, JP
Thomas Arrhenius - Del Mar CA, US
David Wallace - San Diego CA, US
Mi Chen - San Diego CA, US
Sovouthy Tith - San Diego CA, US
Yoshiyuki Ono - Shizuoka, JP
Yoshiaki Watanabe - Tokyo, JP
Assignee:

Chugai Seiyaku Kabushiki Kaisha - Tokyo
International Classification:

C07D 405/12
C07D 407/12
C07D 311/12
US Classification:

549289, 544302, 548187
Abstract:

Novel compounds composition capable of inhibiting TNFα and having antiimmunoinflammatory and autoimmune properties useful in a pharmaceutical composition, such as for a drug containing this as an active ingredient; and a therapeutic method with the use of these novel compounds.

Malonyl-Coa Decarboxylase Inhibitors Useful As Metabolic Modulators
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US Patent:

7279477, Oct 9, 2007
Filed:

Jan 22, 2002
Appl. No.:

10/466926
Inventors:

Thomas Arrhenius - Del Mar CA, US
Mi Chen - San Diego CA, US
Jie Fei Cheng - Carlsbad CA, US
Yujin Huang - San Diego CA, US
Alex Michael Nadzan - Encinitas CA, US
Sovouthy Tith - San Diego CA, US
David Mark Wallace - San Diego CA, US
Bin Liu - Los Angeles CA, US
Masahiro Nishimoto - Susono, JP
Gary D. Lopaschuk - Edmonton, CA
Jason R. Dyck - Sherwood Park, CA
Assignee:

Chugai Seiyaku Kabushiki Kaisha - Tokyo
International Classification:

A61K 31/5375
C07D 265/30
US Classification:

5142378, 544106, 544158, 544159, 544160, 5142312, 5142375, 548240, 5483001, 5483351, 5483561
Abstract:

The present invention relates to novel compounds (I), their prodrugs, and the pharmaceutically acceptable salts as well as pharmaceutical compositions containing such compounds useful in treating certain metabolic diseases and diseases modulated by the inhibition of the enzyme malonyl-coenzyme A decarboxylase (malonyl-CoA decarboxylase, MCD). In particular, the invention relates to compounds and compositions and the methods for the prophylaxis, management and treatment of cardiovascular diseases, diabetes, acidosis, cancers, and obesity through the inhibition of malonyl-coenzyme A decarboxylase.

Method For Preparing Imidazole Derivatives
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US Patent:

7385063, Jun 10, 2008
Filed:

Jan 22, 2002
Appl. No.:

10/466856
Inventors:

Thomas Arrhenius - Del Mar CA, US
Mi Chen - San Diego CA, US
Jie Fei Cheng - Carlsbad CA, US
Yujin Huang - San Diego CA, US
Alex Michael Nadzan - Encinitas CA, US
Sovouthy Tith - San Diego CA, US
Masayuki Haramura - Chiba, JP
David Mark Wallace - San Diego CA, US
Steve Joel Brown - San Diego CA, US
Charles Stanford Harmon - Rancho Santa Fe CA, US
Lin Zhang - San Diego CA, US
Gary D. Lopaschuk - Edmonton, CA
Jason R. Dyck - Sherwood Park, CA
Assignee:

Chugai Seiyaku Kabushiki Kaisha - Tokyo
International Classification:

C07D 233/00
C07D 233/02
A01N 43/50
A61K 31/415
US Classification:

5483001, 514396
Abstract:

The present invention relates to methods for the prophylaxis, management and treatment of certain diseases modulated by the inhibition of the enzyme malonyl-coenzyme A decarboxylase (malonyl-CoA decarboxylase, MCD) by the administration of a composition containing as an active ingredient a compound according to Formula I. In particular, the invention relates to methods for the prophylaxis, management and treatment of cardiovascular diseases, diabetes, acidosis, cancers, and obesity through the administration of a compound which inhibits malonyl-coenzyme A decarboxylase activity. The present invention also includes within its scope the novel process for the preparation of certain compounds.

Piperidine Compounds Useful As Malonyl-Coa Decarboxylase Inhibitors
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US Patent:

7449482, Nov 11, 2008
Filed:

Jul 28, 2004
Appl. No.:

10/900705
Inventors:

Jie Fei Cheng - Carlsbad CA, US
Mi Chen - San Diego CA, US
Thomas Arrhenius - Del Mar CA, US
Mark E. Wilson - Ramona CA, US
Gary D. Lopaschuk - Edmonton, CA
Jason R. Dyck - Sherwood Park, CA
Rossy Serafimov - Metz, FR
Assignee:

Chugai Seiyaku Kabushiki Kaisha - Tokyo
International Classification:

A61K 31/4468
US Classification:

514321, 546198
Abstract:

The present invention provides methods for the use of compounds as depicted by structure I, pharmaceutical compositions containing the same, and methods for the prophylaxis, management and treatment of metabolic diseases and diseases modulated by MCD inhibition. The compounds disclosed in this invention are useful for the prophylaxis, management and treatment of diseases involving in malonyl-CoA regulated glucose/fatty acid metabolism pathway. In particular, these compounds and pharmaceutical composition containing the same are indicated in the prophylaxis, management and treatment of cardiovascular diseases, diabetes, cancer and obesity.

Malonyl-Coa Decarboxylase Inhibitors Useful As Metabolic Modulators
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US Patent:

7524969, Apr 28, 2009
Filed:

Jan 22, 2002
Appl. No.:

10/466923
Inventors:

Thomas Arrhenius - Del Mar CA, US
Mi Chen - San Diego CA, US
Jie Fei Chang - Carlsbad CA, US
Yujin Huang - San Diego CA, US
Alex Michael Nadzan - Encinitas CA, US
Richard Julius Penuliar - San Diego CA, US
David Mark Wallace - San Diego CA, US
Lin Zhang - San Diego CA, US
Gary D. Lopaschuk - Edmonton, CA
Jason R. Dyck - Sherwood Park, CA
Assignee:

Chugai Seiyaku Kabushiki Kaisha - Tokyo
International Classification:

C07D 277/00
US Classification:

548190
Abstract:

The present invention relates to novel compounds (I), their prodrugs, and the pharmaceutically acceptable salts as well as pharmaceutical compositions containing such compounds useful in treating certain metabolic diseases and diseases modulated by the inhibition of the enzyme malonyl-coenzyme A decarboxylase (malonyl-CoA decarboxylase, MCD). In particular, the invention relates to compounds and compositions and the methods for the prophylaxis, management and treatment of cardiovascular diseases, diabetes, acidosis, cancers, and obesity through the inhibition of malonyl-coenzyme A decarboxylase.

Coumarin Derivatives Useful As Tnfα Inhibitors
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US Patent:

7709664, May 4, 2010
Filed:

Sep 13, 2005
Appl. No.:

11/225940
Inventors:

Jie Fei Cheng - Carlsbad CA, US
Thomas Arrhenius - Del Mar CA, US
David Wallace - San Diego CA, US
Mi Chen - San Diego CA, US
Sovouthy Tith - San Diego CA, US
Hirotaka Kashiwagi - Shizuoka, JP
Yoshiyuki Ono - Shizuoka, JP
Yoshiaki Watanabe - Tokyo, JP
Assignee:

Chugai Seiyaku Kabushiki Kaisha - Tokyo
International Classification:

C07D 311/12
US Classification:

549289
Abstract:

Novel compounds composition capable of inhibiting TNFα and having anti immunoinflammatory and autoimmune properties useful in a pharmaceutical composition, such as for a drug containing this as an active ingredient; and a therapeutic method with the use of these novel compounds.

Coumarin Derivatives Useful As Tnfα Inhibitors
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US Patent:

7872142, Jan 18, 2011
Filed:

Mar 18, 2010
Appl. No.:

12/726986
Inventors:

Jie Fei Cheng - Carlsbad CA, US
Thomas Arrhenius - Del Mar CA, US
David Wallace - San Diego CA, US
Mi Chen - San Diego CA, US
Sovouthy Tith - San Diego CA, US
Hirotaka Kashiwagi - Shizuoka, JP
Yoshiyuki Ono - Shizuoka, JP
Yoshiaki Watanabe - Tokyo, JP
Assignee:

Chugai Seiyaku Kabushiki Kaisha - Tokyo
International Classification:

C07D 405/06
US Classification:

5462831, 549289
Abstract:

Novel compounds composition capable of inhibiting TNFα and having antiimmunoinflammatory and autoimmune properties useful in a pharmaceutical composition, such as for a drug containing this as an active ingredient; and a therapeutic method with the use of these novel compounds.

Piperidine Compounds Useful As Malonyl-Coa Decarboxylase Inhibitors
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US Patent:

8080665, Dec 20, 2011
Filed:

Oct 3, 2008
Appl. No.:

12/245558
Inventors:

Jie Fei Cheng - San Diego CA, US
Mi Chen - San Diego CA, US
Thomas Arrhenius - Del Mar CA, US
Mark E. Wilson - Ramona CA, US
Gary D. Lopaschuk - Edmonton, CA
Jason R. Dyck - Sherwood Park, CA
Rossy Serafimov - Las Vegas NV, US
Assignee:

Chugai Seiyaku Kabushiki Kaisha - Tokyo
International Classification:

A61K 31/4468
C07D 211/58
US Classification:

546198, 514321
Abstract:

The present invention provides methods for the use of compounds as depicted by structure I, pharmaceutical compositions containing the same, and methods for the prophylaxis, management and treatment of metabolic diseases and diseases modulated by MCD inhibition. The compounds disclosed in this invention are useful for the prophylaxis, management and treatment of diseases involving in malonyl-CoA regulated glucose/fatty acid metabolism pathway. In particular, these compounds and pharmaceutical composition containing the same are indicated in the prophylaxis, management and treatment of cardiovascular diseases, diabetes, cancer and obesity.