Michael Joseph Chapman

US Patent:

20190145954, May 16, 2019

Filed:

May 11, 2017

Appl. No.:

16/300491

Inventors:

Michael P. Chapman - Denver CO, US

International Classification:

G01N 33/49
A61K 31/4439
A61F 2/01
A61F 2/82
A61M 25/10
A61M 1/36
G01N 33/86
G01N 11/14

Abstract:

In some embodiments, the invention provides a method for identifying a patient suffering from or suspected of suffering in from a disease associated with the cardiovascular system that is having a subnormal response to the treatment for the disease comprising: subjecting a blood sample from a patient being treated for a disease to a viscoelastic analysis in the presence of a known amount of a thrombolytic agent, to obtain a coagulation characteristic value of the patient; and comparing the coagulation characteristic value of the patient to a coagulation characteristic value of a healthy individual, wherein a difference in the coagulation characteristic value of the patient as compared to the coagulation characteristic value of the healthy individual identifies the patient as a patient having a subnormal response to treatment.

US Patent:

20190072570, Mar 7, 2019

Filed:

Jun 7, 2016

Appl. No.:

15/580968

Inventors:

- Denver CO, US
Michael P. CHAPMAN - Denver CO, US

International Classification:

G01N 33/86
G01N 33/49
G01N 11/02
A61B 5/02

Abstract:

In some embodiments, the invention provides an in vitro method for identifying a patient as likely as likely to require a transfusion of at least six units of blood in six hours or less. The method comprise, consists essentially of, or consists of (a) analyzing a sample of blood from a patient with a viscoelastic analysis assay to obtain a coagulation characteristic value that is independent of time of the patient; and (b) comparing the coagulation characteristic value of the patient to a coagulation characteristic value that is independent of time of a control, wherein the coagulation characteristic value of the patient that is lower than the coagulation characteristic value of the control identifies the patient as likely to require a transfusion of at least six units of blood in six hours or less.

US Patent:

20180011116, Jan 11, 2018

Filed:

Jul 31, 2017

Appl. No.:

15/664565

Inventors:

- Denver CO, US
Michael P. Chapman - Denver CO, US

International Classification:

G01N 33/86
A61B 5/02

Abstract:

The invention provides methods for identifying a patient as likely to have an onset of massive hemorrhage. In one embodiment, the invention provides a method for identifying a patient as likely to have an onset of massive hemorrhage, the method comprising measuring at least one of first coagulation characteristic parameter reflective of a clotting time in a sample of blood of the patient, a second coagulation characteristic parameter reflective of clot formation in a sample of blood of the patient using the viscoelastic assay to obtain a second result; a third coagulation characteristic parameter reflective of clot strength in a sample of blood of the patient using the viscoelastic assay to obtain a third result; and a fourth coagulation characteristic parameter reflective of clot lysis in a sample of blood of the patient using the viscoelastic assay to obtain a fourth result; wherein, a positive for at least one of the first result, second result, third result and fourth result identifies the patient as likely to have an onset of massive hemorrhage.

US Patent:

20150109146, Apr 23, 2015

Filed:

Oct 14, 2014

Appl. No.:

14/513526

Inventors:

- Boulder CO, US
Michael Chapman - Arvada CO, US
Amanda Anderson - Boulder CO, US
Gerry Wiener - Boulder CO, US
Seth Linden - Westminster CO, US
Crystal Burghardt - Evergreen CO, US

Assignee:

UNIVERSITY CORPORATION FOR ATMOSPHERIC RESEARCH - Boulder CO

International Classification:

G08G 1/0967

US Classification:

340905

Abstract:

A method and system for assessing road conditions is provided. The method includes determining a road hazard condition for a road segment that may include a precipitation type, a pavement condition, and a visibility level. The precipitation type may be determined using radar data, satellite cloud classification data, weather station air temperature data, wiper status, mobile air data, speed ratio, or headlight status. The pavement condition may be determined using pavement temperature, precipitation type, automatic brake system status, traction status or a stability control observation, and a yaw rate. The visibility level may be determined using wind speed, relative humidity, percentage of fog lights on, percentage of high beams on, speed ratio, station visibility, station-reported visibility type, wildfire existence, wind direction, a dust existence indicator.