Michael A Coleman

US Patent:

8309342, Nov 13, 2012

Filed:

Dec 3, 2008

Appl. No.:

12/746334

Inventors:

Ron Stubbers - Houston TX, US
Michael E. Coleman - Houston TX, US

Assignee:

InGeneron, Inc. - Houston TX

International Classification:

C12P 1/00
C12M 1/00

US Classification:

435267, 4352831

Abstract:

A unitary apparatus for isolating cells from adipose tissue including a lipid separation processor with a dispersing head equipped with a plurality of ports and a digestion chamber for dissociation of the constituent cells disposed in adipose tissue. The lipid separating apparatus is useful for the separation of lipids and adipocytes from a mixed cell population. A cell seeding chamber may be attached to the cell isolation apparatus. The components of the apparatus may be packaged in modular kit form.

US Patent:

20100310527, Dec 9, 2010

Filed:

Jan 8, 2010

Appl. No.:

12/684263

Inventors:

Eckhard U. Alt - Houston TX, US
Michael E. Coleman - The Woodlands TX, US

Assignee:

BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM - Austin TX
INGENERON, INC. - Houston TX

International Classification:

A61K 35/12
C12N 5/071
A61P 9/00

US Classification:

424 937, 435325, 435395

Abstract:

Methods and compositions are provided for lineage predetermination of cellular transplants including through liposome mediated transfection with aqueous protein extracts from populations of differentiated mammalian cells, or cellular fractions thereof, wherein the differentiated mammalian cells are enriched in one or more of adipocytes, chondrocytes, endothelial cells, hepatocytes, cardiomyocytes, smooth muscle cells, skeletal muscle cells, cardiac pacemaker cells, Schwann cells, pancreatic islet cells, hematopoietic cells, myeloblasts, neurons, and osteoblasts.

US Patent:

20120195863, Aug 2, 2012

Filed:

Dec 16, 2011

Appl. No.:

13/329143

Inventors:

Eckhard U. Alt - Houston TX, US
Michael E. Coleman - Houston TX, US
Ron Stubbers - Houston TX, US

International Classification:

A61K 35/12
C12M 1/40
C12N 5/077

US Classification:

424 937, 435325, 4352831

Abstract:

This document describes methods and an apparatus for recovery of a cell-enriched matrix and cells (e.g., regenerative cells) from a tissue sample. In some embodiments, at least two rounds of acceleration and deceleration are performed.

US Patent:

20120219561, Aug 30, 2012

Filed:

Aug 2, 2010

Appl. No.:

13/387852

Inventors:

Eckhard U. Alt - Houston TX, US
Ralph B. Arlinghaus - Bellaire TX, US
Michael E. Coleman - Houston TX, US

Assignee:

Ingeneron, Inc. - Houston TX
Board of Regents, The University of Texas System - Austin TX

International Classification:

A61K 39/395
A61K 31/7088
A61P 35/04

US Classification:

4241581, 4241721, 514 44 A

Abstract:

This document provides prophylactic methods for reducing cancer metastasis by targeting LCN2, MMP9, and CX-CR4.

US Patent:

20130115697, May 9, 2013

Filed:

Nov 3, 2011

Appl. No.:

13/385599

Inventors:

Eckhard U. Alt - Houston TX, US
Michael E. Coleman - Houston TX, US
Ron Stubbers - Houston TX, US

International Classification:

C12N 5/071

US Classification:

435379

Abstract:

This document describes methods and an apparatus for recovery of cells from a tissue sample. In some embodiments, at least two rounds of acceleration and deceleration are performed.

US Patent:

20130252336, Sep 26, 2013

Filed:

May 16, 2013

Appl. No.:

13/896246

Inventors:

Michael Coleman - Houston TX, US
Jody Vykoukal - Houston TX, US

Assignee:

INGENERON - Houston TX

International Classification:

C12N 5/078

US Classification:

435378

Abstract:

Methods for recovering target cells using degradable three dimensional matrices are described.

US Patent:

20130260459, Oct 3, 2013

Filed:

May 16, 2013

Appl. No.:

13/896234

Inventors:

Michael Coleman - Houston TX, US
Jody Vykoukal - Houston TX, US

Assignee:

Ingeneron - Houston TX

International Classification:

C12N 5/09
C12N 5/071

US Classification:

435374

Abstract:

Methods for obtaining and preserving target cells using degradable three dimensional matrices are described.

US Patent:

20130337551, Dec 19, 2013

Filed:

Oct 26, 2012

Appl. No.:

13/661689

Inventors:

Michael Coleman - Houston TX, US

Assignee:

InGeneron Inc. - Houston TX

International Classification:

C12N 5/071

US Classification:

4352831

Abstract:

A unitary apparatus for isolating cells from adipose tissue including a lipid separation processor with a dispersing head equipped with a plurality of ports and a digestion chamber for dissociation of the constituent cells disposed in adipose tissue. The lipid separating apparatus is useful for the separation of lipids and adipocytes from a mixed cell population. A cell seeding chamber may be attached to the cell isolation apparatus. The components of the apparatus may be packaged in modular kit form.