Michael R Daley

US Patent:

59286490, Jul 27, 1999

Filed:

May 31, 1995

Appl. No.:

8/455751

Inventors:

Michael Joseph Daley - Yardley PA
Phillip Wayne Hayes - Warwick NY

Assignee:

American Cyanamid Company - Madison NJ

International Classification:

A61K 39145
A61K 3912
A61K 3902
A61K 39295

US Classification:

4242111

Abstract:

A method of reversing or preventing immunosuppression or antigenic interference associated with combination vaccines in mammals, is disclosed. Cytokines, or cytokine inducer, are administered in conjunction with the combination vaccine. The cytokine or cytokine inducer can be administered concurrently with or subsequently to the vaccine, and can be recombinantly produced or isolated from cell culture.

US Patent:

53426126, Aug 30, 1994

Filed:

Dec 20, 1991

Appl. No.:

7/812894

Inventors:

Michael J. Daley - Yardley PA
William D. Steber - Ledgewood NJ
Gary J. Furda - Trenton NJ
Paul A. Johnston - Langhorne PA
Elizabeth R. Oldham - Newtown PA

Assignee:

American Cyanamid Company - Wayne NJ

International Classification:

A61K 4505

US Classification:

424 851

Abstract:

A therapeutic composition which contains a potentiating or safening amount of an aqueous surfactant in combination with a bactericidal agent and/or a biological response modifier is described herein. The disclosure further describes an improved method for treating mastitis by administering the composition to an afflicted mammal. Additionally, the disclosure describes a method for screening suitable formulations for treating infectious diseases.

US Patent:

53364880, Aug 9, 1994

Filed:

Jun 29, 1992

Appl. No.:

7/905969

Inventors:

Michael J. Daley - Yardley PA
Gary J. Furda - Trenton NJ
Phillip W. Hayes - Rushland PA

Assignee:

American Cyanamid Company - Wayne NJ

International Classification:

A61K 3702

US Classification:

424 852

Abstract:

Cytokines are useful for the ability to improve the natural defense system of the involuting mammary gland. In addition to the immunopotentiating activity, cytokines accelerate the normal physiology of involution of the mammary gland and thereby afford further protection against new infections of mammals. The involuting mammary gland is very susceptible to infection during the early stages of involution and therefore decreasing the period of highest susceptibility while also improving the natural defense mechanisms is of great advantage over most therapies. Used alone, in various cytokine combinations, or in combination with other therapeutics, cytokines protect the mammary gland and cure existing infections and are particularly useful during cessation of lactation and early reinitiating of lactation.

US Patent:

60109998, Jan 4, 2000

Filed:

Jun 2, 1995

Appl. No.:

8/459906

Inventors:

Michael Joseph Daley - Yardley PA
Brian Lee Buckwalter - Yardley PA
Susan Mancini Cady - Yardley PA
Hong-Ming Shieh - Langforne PA
Peter Bohlen - Peekskill NY
Andrew P. Seddon - Monroe NY

Assignee:

American Cyanamid Company - Madison NJ

International Classification:

A01N 6100
A01N 3718

US Classification:

514 2

Abstract:

The present invention relates to physiologically-active derivatized natural and recombinant mammalian and human proteins and polypeptides. The invention provides chemical methods for derivatizing natural and recombinantly-derived proteins or polypeptides containing cysteine residues, either naturally or through site specific mutageneses. The pharmaceutical compositions containing said derivatized proteins and/or polypeptides are formulated to provide stable, long-acting compositions of such proteins and/or polypeptides, previously difficult to achieve.

US Patent:

59519720, Sep 14, 1999

Filed:

Feb 6, 1995

Appl. No.:

8/383621

Inventors:

Michael Joseph Daley - Yardley PA
Brian Lee Buckwalter - Yardley PA
Susan Mancini Cady - Yardley PA
Hong-Ming Shieh - Langforne PA
Peter Bohlen - Peekskill NY
Andrew P. Seddon - Monroe NY

Assignee:

American Cyanamid Company - Madison NJ

International Classification:

A61K 3819
A61K 3827
A61K 3818

US Classification:

424 852

Abstract:

The present invention relates to physiologically-active derivatized natural and recombinant mammalian and human proteins and polypeptides. The invention provides chemical methods for derivatizing natural and recombinantly-derived proteins or polypeptides containing cysteine residues, either naturally or through site specific mutageneses. The pharmaceutical compositions containing the derivatized proteins and/or polypeptides are formulated to provide stable, long-acting compositions of such proteins and/or polypeptides, previously difficult to achieve.

US Patent:

20170224072, Aug 10, 2017

Filed:

Oct 15, 2015

Appl. No.:

15/519226

Inventors:

- Princeton NJ, US
- Neenah WI, US
Michael E. Graves - Princeton NJ, US
William R. Parcells - Princeton NJ, US
Jennifer A. Tuetken - Princeton NJ, US
Vladimir Anokhin - Princton NJ, US
Daniel C. Sosa - US NJ, US
Michael A. Daley - Neenah WI, US
Bryan J. Semkuley - Roswell GA, US
Clarice M. Theisen - Roswell GA, US
Lynn R. Healey - Neenah WI, US
Elizabeth W. Clubb - Atlanta GA, US
Richmond A. Hornby - Milford CT, US
Adam I. Lehman - Milford CT, US
Leland R. Adams - Milford CT, US
Jeffrey Randsen - Milford CT, US

Assignee:

Michael Graves Design Group, Inc. - Princeton NJ

International Classification:

A45B 9/02
A45B 1/04
A45B 9/04

Abstract:

A walking stick can include a handle () including a head (). The head () can include at least one internal reinforcement member (). The at least one internal reinforcement member () can have a shape that is substantially the same as a shape of the head (). The bathing wand can include a neck () and a shaft (). The bathing wand can also include a foot () for engaging the ground. The foot () can be coupled to the shaft (). In some aspects, the foot () can include at least two arms () extending from a top portion () towards a bottom portion () of the foot (). Each of the at least two arms () can be coupled together through a base () of the of the bottom portion (). In some aspects, at least one arm () can form a loop ().