Disclosed are compositions and methods for modulating protein trafficking and treating or preventing disorders characterized by impaired protein trafficking. Also disclosed are methods for identification of compounds that rescue protein trafficking defects and methods of enhancing protein production.
Compounds and compositions are provided for treatment or amelioration of one or more disorders characterized by defects in protein trafficking. A method of treating a disorder characterized by impaired protein trafficking includes administering to a subject or contacting a cell with a compound of Formula I: [formula here] or pharmaceutically acceptable salts or derivatives thereof.
Monoclonal Antibodies Against Her2 Epitope And Methods Of Use Thereof
- Cambridge MA, US Michael J. DeVIT - Sudbury MA, US Eric M. KRAULAND - Lebanon NH, US Timothy B. LOWINGER - Carlisle MA, US Peter U. PARK - Somerville MA, US Bianka PRINZ - Lebanon NH, US Aleksandr V. YURKOVETSKIY - Littleton MA, US
This invention provides fully human monoclonal antibodies that recognize HER2. The invention further provides methods of using such monoclonal antibodies in a variety of therapeutic, diagnostic, and prophylactic indications.
Monoclonal Antibodies Against Her2 Epitope And Methods Of Use Thereof
- Cambridge MA, US Michael J. DeVIT - Sudbury MA, US Eric M. KRAULAND - Lebanon NH, US Timothy B. LOWINGER - Carlisle MA, US Peter U. PARK - Somerville MA, US Bianka PRINZ - Lebanon NH, US Aleksandr V. YURKOVETSKIY - Littleton MA, US
This invention provides fully human monoclonal antibodies that recognize HER2. The invention further provides methods of using such monoclonal antibodies in a variety of therapeutic, diagnostic, and prophylactic indications.
Monoclonal Antibodies Against Her2 Epitope And Methods Of Use Thereof
- Cambridge MA, US Michael J. DeVit - Sudbury MA, US Eric M. Krauland - Lebanon NH, US Timothy B. Lowinger - Carlisle MA, US Peter U. Park - Somerville MA, US Bianka Prinz - Lebanon NH, US Aleksandr V. Yurkovetskiy - Littleton MA, US
This invention provides fully human monoclonal antibodies that recognize HER2. The invention further provides methods of using such monoclonal antibodies in a variety of therapeutic, diagnostic, and prophylactic indications.
Monoclonal Antibodies Against Her2 Epitope And Methods Of Use Thereof
- Cambridge MA, US Michael J. DeVit - Sudbury MA, US Eric M. Krauland - Lebanon NH, US Timothy B. Lowinger - Carlisle MA, US Peter U. Park - Somerville MA, US Bianka Prinz - Lebanon NH, US Aleksandr V. Yurkovetskiy - Littleton MA, US
This invention provides fully human monoclonal antibodies that recognize HER2. The invention further provides methods of using such monoclonal antibodies in a variety of therapeutic, diagnostic, and prophylactic indications.