Michael T Draper

US Patent:

RE39050, Mar 28, 2006

Filed:

Feb 27, 2003

Appl. No.:

10/375274

Inventors:

Michael W. Draper - Carmel IN, US
Larry J. Black - Franklin IN, US

Assignee:

Eli Lilly and Company - Indianapolis IN

International Classification:

A01N 43/12

US Classification:

514443

Abstract:

A method of inhibiting bone loss or resorption, or lowering serum cholesterol, comprising administering to a human in need thereof a compound having the formula or a pharmaceutically acceptable salt or solvate thereof, in a low dosage amount. Also encompassed by the invention is a a pharmaceutical formulation in unit dosage form comprising, per unit dosage, a low dosage amount.

US Patent:

20030116280, Jun 26, 2003

Filed:

Aug 20, 2002

Appl. No.:

10/224687

Inventors:

David Robinson - Santa Cruz CA, US
Michael Draper - San Jose CA, US

International Classification:

C23F001/00
C23C016/00

US Classification:

156/345370, 118/725000

Abstract:

An apparatus and method are provided for insulating a seal () made of a polymeric material in a pressurized, evacuated or exhausted process chamber () that reduces damage due to heat transferred to the seal from the chamber. The chamber () includes a wall () having an aperture () therein, a flange () disposed about the aperture, and an insulator () between the flange and a fixture () to insulate the seal between the flange and the fixture. Generally, the insulator () includes a cooling tube or loop () having a sidewall (262) overlying and attached to the flange (), and a cap () overlying the loop. The cap () has a sealing surface () against which the seal () seats. Fluid may be passed through the loop () to reduce heat transferred to the seal (). Preferably, the flange (), the loop (), and the cap (), are made of quartz or a glass, and the sidewall () of the loop is welded to the flange and the cap. More preferably, the loop () functions as a light pipe to direct heat radiating from the chamber () away from the seal ().

US Patent:

54571162, Oct 10, 1995

Filed:

Oct 15, 1993

Appl. No.:

8/138642

Inventors:

Larry J. Black - Indianapolis IN
George J. Cullinan - Trafalgar IN
Michael W. Draper - Carmel IN
Charles D. Jones - Indianapolis IN
David E. Seyler - Greenfield IN

Assignee:

Eli Lilly and Company - Indianapolis IN

International Classification:

A61K 31445
A61K 3140
A61K 3138

US Classification:

514324

Abstract:

A method of inhibiting uterine fibrosis comprising administering to a human or other mammal in need of treatment an effective amount of a compound having the formula ##STR1## Wherein R. sup. 1 and R. sup. 3 are independently hydrogen, ##STR2## wherein Ar is optionally substituted phenyl; wherein R. sup. 2 is selected from the group consisting of pyrrolidino and piperidino, a pharmaceutically acceptable salt or solvate thereof.

US Patent:

56936567, Dec 2, 1997

Filed:

Apr 14, 1995

Appl. No.:

8/422387

Inventors:

Larry J. Black - Indianapolis IN
George J. Cullinan - Trafalgar IN
Michael W. Draper - Carmel IN
Charles D. Jones - Indianapolis IN
David E. Seyler - Greenfield IN

Assignee:

Eli Lilly and Company - Indianapolis IN

International Classification:

A61K 31445
A61K 3140
A61K 3138

US Classification:

514324

Abstract:

A method of inhibiting endometriosis comprising administering to a human in need of treatment an effective amount of a compound having the formula ##STR1## Wherein R. sup. 1 and R. sup. 3 are independently hydrogen, --CH. sub. 3, ##STR2## wherein Ar is optionally substituted phenyl; R. sup. 2 is selected from the group consisting of pyrrolidine and piperidino; or a pharmaceutically acceptable salt of solvate thereof.

US Patent:

57475105, May 5, 1998

Filed:

Jan 27, 1997

Appl. No.:

8/788984

Inventors:

Michael W. Draper - Carmel IN

Assignee:

Eli Lilly and Company - Indianapolis IN

International Classification:

A61K 3144
C07D40900

US Classification:

514333

Abstract:

A method of inhibiting bone loss or resorption, or lowering serum cholesterol, comprising administering to a human in need thereof a compound having the formula ##STR1## or a pharmaceutically acceptable salt or solvate thereof, in a low dosage amount. Also encompased by the invention is a a pharmaceutical formulation in unit dosage form comprising, per unit dosage, a low dosage amount.

US Patent:

54788471, Dec 26, 1995

Filed:

Mar 2, 1994

Appl. No.:

8/205012

Inventors:

Michael W. Draper - Carmel IN

Assignee:

Eli Lilly and Company - Indianapolis IN

International Classification:

A61K 3144
A61K 3140
A61K 3706

US Classification:

514333

Abstract:

A method of inhibiting bone loss or resorption, or lowering serum cholesterol, comprising administering to a human in need thereof a compound having the formula ##STR1## or a pharmaceutically acceptable salt or solvate thereof, in a low dosage amount. Also encompased by the invention is a a pharmaceutical formulation in unit dosage form comprising, per unit dosage, a low dosage amount.

US Patent:

54610656, Oct 24, 1995

Filed:

Oct 15, 1993

Appl. No.:

8/138643

Inventors:

Larry J. Black - Indianapolis IN
George J. Cullinan - Trafalgar IN
Michael W. Draper - Carmel IN
Charles D. Jones - Indianapolis IN
David E. Seyler - Greenfield IN

Assignee:

Eli Lilly and Company - Indianapolis IN

International Classification:

A61K 31445
A61K 3140
A61K 3138

US Classification:

514324

Abstract:

A method of inhibiting endometriosis comprising administering to a human in need of treatment an effective amount of a compound having the formula ##STR1## Wherein R. sup. 1 and R. sup. 3 are independently hydrogen, --CH. sub. 3, ##STR2## wherein Ar is optionally substituted phenyl; R. sup. 2 is selected from the group consisting of pyrrolidine and piperidino; or a pharmaceutically acceptable salt of solvate thereof.

US Patent:

56417900, Jun 24, 1997

Filed:

Apr 14, 1995

Appl. No.:

8/422417

Inventors:

Michael W. Draper - Carmel IN

Assignee:

Eli Lilly and Company - Indianapolis IN

International Classification:

A61K 3144
A61K 3140

US Classification:

514333

Abstract:

A method of inhibiting bone loss or resorption, or lowering serum cholesterol, comprising administering to a human in need thereof a compound having the formula ##STR1## or a pharmaceutically acceptable salt or solvate thereof, in a low dosage amount. Also encompased by the invention is a a pharmaceutical formulation in unit dosage form comprising, per unit dosage, a low dosage amount.