Michael S Flanagan

US Patent:

20130217756, Aug 22, 2013

Filed:

Oct 25, 2011

Appl. No.:

13/881415

Inventors:

Mark Cancilla - Philadelphia PA, US
James John Cunningham - Wayne PA, US
Michael W. Flanagan - Menlo Park CA, US
Henry J. Haringsma - San Francisco CA, US
Denise M. Kenski - San Francisco CA, US
Matthew G. Stanton - Marlton NJ, US
Steven M. Stirdivant - Cary NC, US
Aarron T. Willingham - Mountain View CA, US

Assignee:

MERCK SHARP & DOHME CORP. - Rahway NJ

International Classification:

C07H 21/02

US Classification:

514 44 A, 536 245

Abstract:

The present invention relates to compounds, compositions, and methods for the study, diagnosis, and treatment of traits, diseases and conditions that respond to the modulation of gene expression and/or activity, and/or modulate a gene expression pathway. Specifically, the invention relates to double-stranded nucleic acid molecules including small nucleic acid molecules, such as short interfering nucleic acid (siNA) molecules that are capable of mediating or that mediate RNA interference (RNAi) against target gene expression.

US Patent:

49796232, Dec 25, 1990

Filed:

Oct 13, 1989

Appl. No.:

7/421014

Inventors:

Michael P. Flanagan - Pleasantville NJ

International Classification:

B07B 102
B25F 100

US Classification:

209419

Abstract:

A combined tool for retrieving buried objects comprises an elongate handle having a first digging tool at one end and a second digging tool at the other end, one of said digging tools comprising a digging implement for digging in compacted material, and the other digging tool comprising a sifting implement for sifting loosened material to separate objects buried therein. The handle may be folded to make the tool more compact for storage or carrying, and a comb or toothed device may be attached to the sifting element to facilitate use of the tool in material containing stones, seashells, or the like, or in wet sand or the like.