Michael J Forster

US Patent:

6495529, Dec 17, 2002

Filed:

Apr 16, 2001

Appl. No.:

09/743052

Inventors:

Anthony Booth - Chester NJ
William T. Sherman - Hendersonville NC
Peter Raven - Forth Worth TX
James L. Caffrey - Burelson TX
Thomas Yorio - Burelson TX
Michael Forster - Fort Worth TX
Patricia Gwirtz - Forth Worth TX

Assignee:

Warner-Lambert Company - Morris Plains NJ

International Classification:

A61K 31135

US Classification:

514 55, 514648, 514649, 514912

Abstract:

The present invention provides pharmaceutical compositions which include (-)-pseudoephedrine and a pharmaceutically acceptable carrier, wherein the (-)-pseudoephedrine is substantially-free of (+)-pseudoephedrine. In another embodiment, the present invention provides methods of relieving nasal and bronchial congestion and of inducing pupil dilation which include administering a pharmaceutically effective amount of (-)-pseudoephedrine to a mammal. The (-)-pseudoephedrine used in the present methods is substantially free of (+)-pseudoephedrine and also substantially free of side effects caused by administration of (+)-pseudoephedrine.

US Patent:

20080193915, Aug 14, 2008

Filed:

Sep 29, 2005

Appl. No.:

11/575253

Inventors:

Laszlo Prokai - Mansfield TX, US
Michael J. Forster - Fort Worth TX, US

Assignee:

UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. - Gainesville FL
UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH - Fort Worth TX

International Classification:

C12Q 1/70
G01N 33/00
C12Q 1/00
G01N 33/53
C12Q 1/02

US Classification:

435 5, 436 86, 436 63, 436 94, 435 4, 435 29, 435 792

Abstract:

The subject invention provides novel isotope-labeled dinitrophenylhydrazines (DNPHs) and methods for their use in detecting and/or quantifying carbonyl groups in proteins and other analytes. In particular, the present invention provides novel methods for identifying biomarkers of oxidative stress, which can be used to either forecast or detect diseases and/or conditions associated with oxidative stress. In one embodiment of the invention, isotope-labeled DNPHs are derived from [C]chlorobenzene.

US Patent:

20080242733, Oct 2, 2008

Filed:

Jul 13, 2006

Appl. No.:

11/485928

Inventors:

Anthony Booth - Chester NJ, US
William T. Sherman - Hendersonville NC, US
Peter Raven - Fort Worth TX, US
James L. Caffrey - Burelson TX, US
Thomas Yorio - Burelson TX, US
Michael Forster - Fort Worth TX, US
Patricia Gwirtz - Fort Worth TX, US

International Classification:

A61K 31/137
A61P 11/00

US Classification:

514653

Abstract:

The present invention provides pharmaceutical compositions which include (−)-pseudoephedrine and a pharmaceutically acceptable carrier, wherein the (−)-pseudoephedrine is substantially-free of (+)-pseudoephedrine. In another embodiment, the present invention provides methods of relieving nasal and bronchial congestion and of inducing pupil dilation which include administering a pharmaceutically effective amount of (−)-pseudoephedrine to a mammal. The (−)-pseudoephedrine used in the present methods is substantially free of (+)-pseudoephedrine and also substantially free of side effects caused by administration of (+)-pseudoephedrine.