Thomas A. Osborne - Bloomington IN, US Brian C. Case - Bloomington IN, US Jacob A. Flagle - Bloomington IN, US Andrew K. Hoffa - Bloomington IN, US Michael L. Garrison - Indianapolis IN, US
Assignee:
Cook Incorporated - Bloomington IN
International Classification:
A61F 2/06
US Classification:
623 124
Abstract:
Medical devices for implantation in a body vessel are provided. A medical device according to the invention comprises a support structure and one or more graft members comprising a valve portion and a constraining portion. The support structure has a first, unexpanded configuration and a second, expanded configuration. The constraining portion is adapted to substantially prevent the support structure from achieving the second, expanded configuration. The valve portion is adapted to permit fluid flow through a body vessel in a first direction and substantially prevent fluid flow through the vessel in a second, opposite direction.
Vascular Valves Having Implanted And Target Configurations And Methods Of Preparing The Same
Brian C. Case - Bloomington IN, US Jacob A. Flagle - Indianapolis IN, US Michael L. Garrison - Indianapolis IN, US F. Joseph Obermiller - West Lafayette IN, US Dusan Pavcnik - Portland OR, US
Assignee:
Cook Incorporated - Bloomington IN
International Classification:
A61F 2/06
US Classification:
623 124, 623 238
Abstract:
Described are vascular valve devices for implantation in a patient. The vascular valve devices are designed to compensate for the retraction characteristics of a remodelable material used to form one or more leaflets. Alternatively, or in addition, the devices are designed to reduce retraction of the remodelable leaflet-forming material. Further described are methods for preparing and using these vascular valve devices.
Artificial Valve Prosthesis With Improved Flow Dynamics
Brian C. Case - Bloomington IN, US Jacob A. Flagle - Bloomington IN, US Andrew K. Hoffa - Bloomington IN, US Darin G. Schaeffer - Bloomington IN, US Michael L. Garrison - Indianapolis IN, US
Assignee:
Cook Incorporated - Bloomington IN
International Classification:
A61F 2/06 A61F 2/24
US Classification:
623 126, 623 124, 623 214, 623 218
Abstract:
An expandable venous valve having a support structure that configured to enlarge the area adjacent to the valve structure such that the flow patterns of retrograde flow are modified in a way that facilitates the flushing of the pockets at the base of the valve area to prevent stagnation of bodily fluid, which in the venous system, can lead to thrombus formation. The enlarged pocket areas can be created by forming an artificial sinus adjacent the valve structure in an unsupported section of vessel wall between two support frame section or the support frame can comprise an expanded-diameter intermediate or proximal section that forms an artificial sinus adjacent the valve structure. In another group of embodiments, the attachment pathway between opposing leaflets and the support frame and/or vessel wall comprises a proximal portion that places the leaflets in extended contact with one another and a distal portion forms a large angle with respect to the adjacent walls such that a large pocket is created at the base of the leaflets. In one embodiment, the attachment pathway extends distally along a pair of substantially parallel longitudinal attachment struts to create an extended leaflet contact area, then angles circumferentially and distally from the former along distal attachment struts to define the bottom edge of the leaflets.
Dusan Pavcnik - Portland OR, US Thomas A. Osborne - Bloomington IN, US Brian C. Case - Bloomington IN, US Jacob A. Flagle - Bloomington IN, US Michael L. Garrison - Bloomington IN, US Andrew K. Hoffa - Bloomington IN, US Darin G. Schaeffer - Bloomington IN, US Richard B. Sisken - West Lafayette IN, US
Assignee:
Cook Incorporated - Bloomington IN Oregon Health Science University - Portland OR
International Classification:
A61F 2/06 A61F 2/24
US Classification:
623 124, 623 214, 623 216
Abstract:
An valve prosthesis, such as an artificial venous valve, having a support frame and leaf structure comprising one or more leaflets in which the outer edge of each leaflet engages the inner circumference of the bodily passageway along a serpentine path urged against the passageway by an expandable frame, while the inner edges move in response to fluid to restrict retrograde flow. Optionally, one or more elements can extend from the support frame/leaf structure to provide centering support and/or protection from the leaflet adhering to the vessel wall. In one embodiment, the centering support structure comprises a second or third expandable frames attached to and extending from the proximal and/or distal ends of main valve structure and support frame. In another embodiment, one or more support elements extend outward from the valve support frame to engage the vessel wall to provide greater longitudinal stability.
Brian C. Case - Bloomington IN, US Jacob A. Flagle - Bloomington IN, US Ram H. Paul - Bloomington IN, US Andrew K. Hoffa - Bloomington IN, US Michael L. Garrison - Indianapolis IN, US Joseph F. Obermiller - West Lafayette IN, US
Assignee:
Cook Incorporated - Bloomington IN
International Classification:
A61F 2/06
US Classification:
623 113
Abstract:
Implantable medical devices comprising a support frame and a graft member attached to the support frame. The support frame can define one or more structural features that substantially prevent migration of the graft member along the support frame.
Delivery System That Facilitates Visual Inspection Of An Intraluminal Medical Device
Jacob A. Flagle - Bloomington IN, US Brian C. Case - Bloomington IN, US Andrew K. Hoffa - Bloomington IN, US Michael L. Garrison - Indianapolis IN, US
Assignee:
Cook Incorporated - Bloomington IN
International Classification:
A61F 2/84
US Classification:
623 123, 623 211, 623 111
Abstract:
Delivery systems, methods of making delivery systems, and methods of treatment are provided. A delivery system according to the invention facilitates a visual inspection of an intraluminal medical device included in the delivery system.
Implantable Medical Device With Constrained Expansion
Thomas A. Osborne - Bloomington IN, US Brian C. Case - Bloomington IN, US Jacob A. Flagle - Bloomington IN, US Andrew K. Hoffa - Bloomington IN, US Michael L. Garrison - Indianapolis IN, US
Assignee:
Cook Medical Technologies LLC - Bloomington IN
International Classification:
A61F 2/06
US Classification:
623 124, 623 214
Abstract:
A medical device comprises a support structure and one or more graft members comprising a valve portion and a constraining portion. The support structure has a first, unexpanded configuration and a second, expanded configuration. The constraining portion is adapted to substantially prevent the support structure from achieving the second, expanded configuration. The valve portion is adapted to permit fluid flow through a body vessel in a first direction and substantially prevent fluid flow through the vessel in a second, opposite direction.
Prosthesis Adapted For Placement Under External Imaging
Brian C. Case - Bloomington IN, US Jacob A. Flagle - Bloomington IN, US Michael L. Garrison - Indianapolis IN, US Andrew K. Hoffa - Bloomington IN, US Ray Leonard, II - Bloomington IN, US
Assignee:
Cook Medical Technologies LLC - Bloomington IN
International Classification:
A61F 11/00
US Classification:
606108
Abstract:
A expandable prosthesis having an imageable structure comprising one or more elements visually distinguishable by an external (e. g. , radiographic or ultrasonic) imaging system, the structure being located about a first axis that corresponds to a structural feature of the prosthesis that is configured to perform a specific function particular to that axis. The imageable structure is configured to assist in the rotational orientation of the prosthesis during placement within the implantation site. In one embodiment, the prosthesis comprises a venous valve that includes imageable elements or structure, such as a pair of radiopaque markers, that defines the orifice of the valve structure such that the orifice can be oriented with a particular anatomical feature under imaging, such as to align the orifice with the long axis of the vessel. In another embodiment, the imageable structure is configured to permit an aperture located about a stent graft to be oriented with a anatomical feature of the vessel, such as a branch vessel opening. The invention includes a method for using imageable structure to confirm that the orientation of the prosthesis within a delivery apparatus is consistent the desired delivery approach to be used.