Michael A Greco

US Patent:

7958605, Jun 14, 2011

Filed:

Jun 11, 2008

Appl. No.:

12/137031

Inventors:

Michael A. Greco - Brooklyn NY, US

International Classification:

B65D 71/00

US Classification:

24288, 206159, 294 872

Abstract:

A cap clip for fastening caps together is realized employing pressure type pincer snaps, allowing complex geometrical shapes to be formed while reducing the use of fasteners. In one embodiment, the cap clip includes a generally triangular base and three pincer snaps formed integrally with the base along the outer perimeter. Preferably, each pincer snap is comprised of a pair of convex walls and a shared clasping section lying along a radius of curvature path that are co-centric.

US Patent:

20100077573, Apr 1, 2010

Filed:

Mar 23, 2009

Appl. No.:

12/408845

Inventors:

MICHAEL A. GRECO - Brooklyn NY, US

International Classification:

A44B 99/00

US Classification:

24457

Abstract:

A cap clip for fastening caps together is realized employing pressure type pincer snaps, allowing complex geometrical shapes to be formed while reducing the use of fasteners. In one embodiment, the cap clip includes a generally triangular base and three pincer snaps formed integrally with the base along the outer perimeter. Preferably, each pincer snap is comprised of a pair of convex walls and a shared clasping section lying along a radius of curvature path that are co-centric. In another embodiment, each pincer snap includes a single convex plate and concave walls of a twin clasping section consisting of two triangular sections with a spacing centrally disposed therebetween. Each triangular section has two outer concave walls extending vertically upward away from the base, and joined laterally to each other along a corresponding rounded edge. Alternatively, concave plates may be used, with a recessed channel formed between each of concave plate and corresponding concave walls of said clasping section for securing the cap therebetween.

US Patent:

20190031618, Jan 31, 2019

Filed:

Oct 3, 2018

Appl. No.:

16/150484

Inventors:

- Beerse, BE
Rui Zhang - Belle Mead NJ, US
Yue-Mei Zhang - Wellesley MA, US
Bin Zhu - Newtown PA, US
Michael H. Parker - Chalfont PA, US
Donald W. Ludovici - Quakertown PA, US
Daniel J. Parks - Downington PA, US
Bart L. DeCorte - Southampton PA, US
Michael N. Greco - Lansdale PA, US

Assignee:

Janssen Pharmaceutica NV - Beerse

International Classification:

C07D 235/18
C07D 401/14
C07D 405/04
C07D 409/14
C07D 401/06
C07D 401/04
C07C 53/18
C07D 417/14
C07D 409/10
C07D 403/04
C07D 405/06
C07D 471/08
C07D 417/06
C07D 405/14

Abstract:

The present invention is directed to benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions mediated by the CB-1 receptor, more particularly, use in the treatment of disorders and conditions responsive to inverse agonism of the CB-1 receptor. More particularly, the compounds of the present invention are useful in the treatment of metabolic disorders.

US Patent:

20170057925, Mar 2, 2017

Filed:

Aug 17, 2016

Appl. No.:

15/239348

Inventors:

- Beerse, BE
Rui Zhang - Belle Mead NJ, US
Michael H. Parker - Chalfont PA, US
Bart L. DeCorte - Southampton PA, US
Michael N. Greco - Lansdale PA, US

Assignee:

Janssen Pharmaceutica NV - Beerse

International Classification:

C07D 231/56
C07D 401/14
C07D 405/14
C07D 409/14
C07D 401/04
C07D 417/14

Abstract:

The present invention is directed to indazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions mediated by the CB-1 receptor; more particularly, use in the treatment of disorders and conditions responsive to inverse agonism of the CB-1 receptor. More particularly, the compounds of the present invention are useful in the treatment of metabolic disorders.

US Patent:

20170057929, Mar 2, 2017

Filed:

Aug 23, 2016

Appl. No.:

15/244372

Inventors:

- Beerse, BE
Rui Zhang - Belle Mead NJ, US
Yue-Mei Zhang - Wellesley MA, US
Bin Zhu - Newtown PA, US
Michael H. Parker - Chalfont PA, US
Donald W. Ludovici - Quakertown PA, US
Daniel J. Parks - Pepperell MA, US
Bart L. DeCorte - Southampton PA, US
Michael N. Greco - Lansdale PA, US

Assignee:

Janssen Pharmaceutica NV - Beerse

International Classification:

C07D 235/18
C07C 53/18
C07D 401/14
C07D 405/14
C07D 409/14
C07D 405/04
C07D 417/14
C07D 471/08
C07D 409/10
C07D 401/06
C07D 417/06
C07D 405/06
C07D 401/04
C07D 403/04

Abstract:

The present invention is directed to benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions mediated by the CB-1 receptor; more particularly, use in the treatment of disorders and conditions responsive to inverse agonism of the CB-1 receptor. More particularly, the compounds of the present invention are useful in the treatment of metabolic disorders.

US Patent:

20160068512, Mar 10, 2016

Filed:

Sep 3, 2015

Appl. No.:

14/844309

Inventors:

- Beerse, BE
Yue-Mei Zhang - Belle Mead NJ, US
Bart L. DeCorte - Southampton PA, US
Michael N. Greco - Lansdale PA, US

Assignee:

JANSSEN PHARMACEUTICA NV - Beerse

International Classification:

C07D 401/12
C07D 417/06
C07D 239/94
C07D 403/04
C07D 401/04
C07D 239/95
C07D 409/14
C07D 403/12
C07D 417/14
C07D 401/14

Abstract:

The present invention is directed to quinazoline derivatives, pharmaceutical compositions containing said derivatives and their use in the treatment of disorders and conditions mediated by the CB-1 receptor; more particularly, in the treatment of disorders and conditions responsive to inverse agonism of the CB-1 receptor. For example, the compounds of the present invention are useful in the treatment of metabolic disorders.