Michael L Irwin

US Patent:

42822106, Aug 4, 1981

Filed:

Dec 20, 1979

Appl. No.:

6/105687

Inventors:

Michael R. Irwin - New City NY

Assignee:

American Cyanamid Co. - Stamford CT

International Classification:

A61K 3912

US Classification:

424 89

Abstract:

There is provided a method for the control of shipping fever pneumonia in cattle, comprising administering to said cattle an immunizing amount of an infectious bovine rhinotracheitis virus vaccine and a potentiating amount of a potentiator therefor, selected from the group consisting of pharmaceutically acceptable salts of dl 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole and pharmaceutically acceptable salts of 1(-)6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole. This invention also relates to a method for reducing morbidity associated with shipping fever pneumonia in cattle by the parenteral treatment of said cattle with from 2 mg/kg to 8 mg/kg of animal body weight of a pharmaceutically acceptable salt of dl 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole or 1(-)6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole and a prophylactically effective amount of infectious bovine rhinotracheitis virus vaccine.