Michael Jeffrey Jaasma

US Patent:

20090240337, Sep 24, 2009

Filed:

Mar 23, 2009

Appl. No.:

12/409359

Inventors:

David Myung - Santa Clara CA, US
Lampros Kourtis - San Francisco CA, US
Michael J. Jaasma - San Francisco CA, US

International Classification:

A61K 9/00
A61B 17/56
B32B 37/12
A61F 2/30
A61P 43/00

US Classification:

623 1811, 1563317, 1562755, 156305, 156 83

Abstract:

A method of attaching an implant to a bone, the implant comprising a hydrated polymer comprising a lubricious hydrated surface and an attachment surface comprising accessible chemical functional groups. The method includes the steps of treating the implant or the bone with an isocyanate-containing compound; placing the attachment surface in apposition to the bone; and allowing the isocyanate-containing compound to cure to bond the implant to the bone. The invention also includes a medical implant having a hydrated polymer comprising an attachment surface comprising a thermoplastic material, the hydrated polymer having an interpenetrating polymer network with at least two polymers, the hydrated polymer having a low coefficient of friction on at least one surface.

US Patent:

20100010114, Jan 14, 2010

Filed:

Jul 7, 2009

Appl. No.:

12/499041

Inventors:

David Myung - Santa Clara CA, US
Michael J. Jaasma - San Francisco CA, US
Lampros Kourtis - San Francisco CA, US

International Classification:

A61K 6/09
C08L 75/08

US Classification:

523114, 525127, 523117

Abstract:

A composition of matter comprising a water-swellable IPN or semi-IPN including a hydrophobic thermoset or thermoplastic polymer and an ionic polymer, articles made from such composition and methods of using such articles. The invention also includes a process for producing a water-swellable IPN or semi-IPN from a hydrophobic thermoset or thermoplastic polymer including the steps of placing an ionizable monomer solution in contact with a solid form of the hydrophobic thermoset or thermoplastic polymer; diffusing the ionizable monomer solution into the hydrophobic thermoset or thermoplastic polymer; and polymerizing the ionizable monomers to form a ionic polymer inside the hydrophobic thermoset or thermoplastic polymer, thereby forming the IPN or semi-IPN.

US Patent:

20100032090, Feb 11, 2010

Filed:

Aug 5, 2009

Appl. No.:

12/536233

Inventors:

David Myung - Santa Clara CA, US
Lampros Kourtis - San Francisco CA, US
Robert Ward - Berkeley CA, US
Michael J. Jaasma - San Francisco CA, US
Keith McCrea - Concord CA, US

International Classification:

B32B 37/15
A61K 6/09
B05D 3/10
A61K 38/00
A61K 38/18
A61K 38/39

US Classification:

1562755, 523115, 424425, 514 12, 427 226, 1563071

Abstract:

An article comprising two chemically grafted polymer layers comprising a hydrogel layer and an end-functionalized polyurethane layer. The invention also includes methods of making and using the article.

US Patent:

20120045651, Feb 23, 2012

Filed:

Aug 26, 2011

Appl. No.:

13/219348

Inventors:

David Myung - Santa Clara CA, US
Michael J. Jaasma - San Francisco CA, US
Lampros Kourtis - Berkeley CA, US
Daniel Chang - Danville CA, US
Curtis W. Frank - Cupertino CA, US

International Classification:

A61L 24/06
B32B 7/04
C08L 75/04
A61K 6/09

US Classification:

4284231, 525130, 525127, 524507

Abstract:

A composition of matter comprising a hydrophobic or hydrophilic (or both) interpenetrating polymer network containing a non-ionic/ionic polymer and a hydrophobic thermoset or thermoplastic polymer, articles made from such composition and methods of preparing such articles. The invention also includes a process for preparing a hydrophobic/hydrophilic IPN or semi-IPN from a hydrophobic thermoset or thermoplastic polymer including the steps of placing an non-ionizable/ionizable monomer solution in contact with a hydrophobic thermoset or thermoplastic polymer; diffusing the monomer solution into the hydrophobic thermoset or thermoplastic polymer; and polymerizing the monomers to form a penetrating polymer inside the hydrophobic thermoset or thermoplastic polymer, thereby forming the IPN or semi-IPN.

US Patent:

20120209396, Aug 16, 2012

Filed:

Jan 10, 2012

Appl. No.:

13/347647

Inventors:

David Myung - Santa Clara CA, US
Michael J. Jaasma - San Francisco CA, US
Lampros Kourtis - Berkeley CA, US
Jeffrey G. Roberts - Germantown TN, US
Vernon Hartdegen - Collierville TN, US

International Classification:

A61F 2/32
A61F 2/30

US Classification:

623 2211, 623 2342, 523113

Abstract:

Orthopedic implants having a bone interface member and a water swellable IPN or semi-IPN with a stiffness, hydration, and/or compositional gradient from one side to the other and physically attached to the bone interface member. The invention also includes an orthopedic implant system including an implant that may conform to a bone surface and a joint capsule. The invention also includes orthopedic implants with water swellable IPN or semi-IPNs including a hydrophobic thermoset or thermoplastic polymer first network and an ionic polymer second network, joint capsules, labral components, and bone interface members. The invention also includes a method of inserting an orthopedic implant having a metal portion and a flexible polymer portion into a joint, including inserting the implant in a joint in a first shape and changing the implant from a first shape to a second shape to conform to a shape of a bone.

US Patent:

20120277807, Nov 1, 2012

Filed:

Jul 5, 2012

Appl. No.:

13/542464

Inventors:

David Myung - Santa Clara CA, US
Michael J. Jaasma - San Francisco CA, US

Assignee:

BIOMIMEDICA, INC. - South San Francisco CA

International Classification:

A61B 17/84

US Classification:

606331

Abstract:

A method of attaching an implant to a bone, the implant comprising a hydrated polymer comprising a lubricious hydrated surface and an attachment surface comprising accessible chemical functional groups. The method includes the steps of treating the implant or the bone with an isocyanate-containing compound; placing the attachment surface in apposition to the bone; and allowing the isocyanate-containing compound to cure to bond the implant to the bone. The invention also includes a medical implant having a hydrated polymer comprising an attachment surface comprising a thermoplastic material, the hydrated polymer having an interpenetrating polymer network with at least two polymers, the hydrated polymer having a low coefficient of friction on at least one surface.

US Patent:

20130103157, Apr 25, 2013

Filed:

Oct 3, 2012

Appl. No.:

13/573788

Inventors:

Lampros Kourtis - Berkeley CA, US
David Myung - Santa Clara CA, US
Daniel Chang - Danville CA, US
Bing Yu - Berkeley CA, US
Timothy Sun - Berkeley CA, US
Michael J. Jaasma - San Francisco CA, US
Vernon Hartdegen - Collierville TN, US

International Classification:

C09J 133/14
A61F 2/30
A61M 5/19
A61K 47/32
B65D 85/00

US Classification:

623 1811, 526312, 524555, 526208, 522 96, 526213, 526217, 526210, 5147726, 206568, 604191

Abstract:

Methods, compositions, and kits for adhering polymers and other materials to another material, and in particular to bone or bone-like structures or surfaces. A composition of matter includes a urethane dimethacrylate-methyl methacrylate copolymer with a plurality of first polymer regions based on urethane dimethacrylate and a plurality of second polymer regions based on methyl methacrylate. The method includes placing an orthopedic joint implant having an attachment surface in a joint space, applying a first non-urethane-containing precursor, a second urethane-containing precursor, and a initiator to the attachment surface; contacting the first and second precursors and the initiator with the joint surface; and copolymerizing the first and second precursors and forming an adhesive copolymer and attaching the implant to the joint.

US Patent:

20130131741, May 23, 2013

Filed:

Nov 21, 2012

Appl. No.:

13/683731

Inventors:

Lampros Kourtis - Berkeley CA, US
Michael J. Jaasma - San Francisco CA, US
David Myung - Santa Clara CA, US
Michael C. Hollis - Collierville TN, US
Vernon Hartdegen - Collierville TN, US

International Classification:

A61F 2/46

US Classification:

606 86 R

Abstract:

Methods, devices, and systems for delivering and attaching flexible implants to a bone or joint surface. An implant container includes a first component for surrounding and enclosing an implant and a second component adapted for maintaining, supporting, and conforming the shape of the implant. The implant container designed to have at least one component attachable to the implant and to a delivery instrument or tool. The implant container component having a material allowing transmission of light through a thickness of the container and a thickness of an attached implant to cure an adhesive placed between the implant and a bone surface. Additionally, embodiments described provide delivery instruments and tools for attaching implants and implants within containers to a joint or bone surface.