Michael S Levin

US Patent:

7700347, Apr 20, 2010

Filed:

Jun 29, 2006

Appl. No.:

11/477259

Inventors:

Michael Levin - Swampscott MA, US

Assignee:

The Forsyth Institute - Boston MA

International Classification:

C12M 3/00

US Classification:

4352884

Abstract:

The invention provides apparatuses, systems, and methods for conducting assays in aquatic animals. The apparatuses, systems, and methods of the invention can be used to identify and/or characterize compounds that modulate morphological, anatomical, or behavioral characteristics. The apparatuses, systems, and methods of the invention can be used to identify and/or characterize compounds that modulate learning or memory.

US Patent:

20080131920, Jun 5, 2008

Filed:

Oct 4, 2006

Appl. No.:

11/543469

Inventors:

Michael Levin - Swampscott MA, US

Assignee:

The Forsyth Institute - Boston MA

International Classification:

C12N 5/00
C12N 5/02
C12Q 1/20
C12N 5/04

US Classification:

435 29, 435375, 435377, 435378

Abstract:

The present invention provides methods for promoting dedifferentiation and/or regeneration by modulating membrane potential and/or intracellular pH in non-naturally regenerating cells.

US Patent:

20100306861, Dec 2, 2010

Filed:

Mar 2, 2010

Appl. No.:

12/716057

Inventors:

Michael Levin - Swampscott MA, US

Assignee:

The Forsyth Institute - Boston MA

International Classification:

G01N 33/50
A01K 1/03

US Classification:

800 3, 119417

Abstract:

The invention provides apparatuses, systems, and methods for conducting assays in aquatic animals. The apparatuses, systems, and methods of the invention can be used to identify and/or characterize compounds that modulate morphological, anatomical, or behavioral characteristics. The apparatuses, systems, and methods of the invention can be used to identify and/or characterize compounds that modulate learning or memory.

US Patent:

20120084242, Apr 5, 2012

Filed:

Oct 4, 2011

Appl. No.:

13/252610

Inventors:

Michael Levin - Swampscott MA, US

Assignee:

MIND OVER MATTER AI, LLC. - Middleton WI

International Classification:

G06N 5/02

US Classification:

706 46

Abstract:

The present invention provides devices, methods, and systems for coupling a rational agent to a quantum process. In particular, the present invention provides rational agents configured to influence a quantum process, or to derive information from a quantum process, and methods and uses thereof.

US Patent:

20120232000, Sep 13, 2012

Filed:

Jul 30, 2010

Appl. No.:

13/387869

Inventors:

Michael Levin - Swampscott MA, US

Assignee:

Tufts University - Boston MA

International Classification:

A61K 38/28
A61K 31/35
C12N 5/0775
C12N 5/0735
C12N 5/071

US Classification:

514 59, 435377, 435325, 435375, 514460

Abstract:

The invention provides methods and compositions for increasing the intracellular sodium concentration in a cell.

US Patent:

20120295346, Nov 22, 2012

Filed:

Jul 22, 2010

Appl. No.:

13/386372

Inventors:

Michael Levin - Swampscott MA, US

Assignee:

Tufts University - Boston MA

International Classification:

C12N 5/02
C12N 5/0735
C12N 5/0775

US Classification:

435366, 435375

Abstract:

The present invention provides methods for controlling proliferation, differentiation, and/or migration of cells by modulating membrane potential through an endogenously expressed channel protein. The present invention also provides methods for identifying candidate instructor cells, as well as therapeutic agents that are useful for modulating (e.g., promote or inhibit) proliferation and differentiation, as well as promoting regeneration of a desired tissue type.

US Patent:

20130245716, Sep 19, 2013

Filed:

Apr 29, 2011

Appl. No.:

13/643797

Inventors:

Daniel Hechavarria - Boston MA, US
David Kaplan - Concord MA, US
Michael Levin - Swampscott MA, US
Susan Braunhut - Wellesley MA, US

Assignee:

Tufts University - Boston MA

International Classification:

A61N 1/44

US Classification:

607 50

Abstract:

The regenerative sleeve encompasses the wound site of an amputated appendage and provides an environment conducive to tissue regeneration. The sleeve includes a tubular reservoir having an outer body that encloses the end of the appendage including the wound site and provides a sealed wound space between the wound site and the outer body. The sleeve also includes a cuff disposed in an opening formed in the outer body, the cuff being configured to fit on the appendage, and an access port disposed on the outer body and configured to allow administration of fluids to the wound space. The sleeve assembly was effective in supporting early stages of murine digit tip regeneration when combined with a porcine urinary bladder matrix (UBM) pepsin digest and electrical stimulation.

US Patent:

50513290, Sep 24, 1991

Filed:

Dec 19, 1989

Appl. No.:

7/452994

Inventors:

Edward B. Caruthers - West Chester PA
Michael L. Levin - Downingtown PA
Catharine E. Looney - Centerville DE
Steven P. Schmidt - Chester Springs PA
Dana S. Smith - Wilmington DE

Assignee:

DXImaging - Lionville PA

International Classification:

G03G 1310

US Classification:

430100

Abstract:

Process for reversal development of a latent electrostatic image in a layer on a conductive support by developing with an electrostatic developer having electrostatically charged toner particles by (a) generating imagewise areas in the layer having different rates of charge decay and/or charge acceptance, (b) charging the layer, (c) allowing formation of an electrostatic image corresponding to the imagewise generated areas by differential charge decay and/or charge acceptance, (d) creating an electrical field to attract toner particles preferentially to the areas of lesser charge, and (e) developing the areas of lesser charge with electrostatically charged toner particles having the same polarity as that of the charged layer. The developed image can be transferred to a receptor surface, e. g. , paper. The process is useful with many type photosensitive masters in preparing reversal images with the use of only one master, toner and film original.