Michael Eric Mcclure

US Patent:

7157466, Jan 2, 2007

Filed:

Jun 28, 2001

Appl. No.:

10/311678

Inventors:

Michael Scott McClure - Durham NC, US
Martin Howard Osterhout - Durham NC, US
Frank Roschangar - Glen Allen VA, US
Mark Joseph Sacchetti - Foster City CA, US

Assignee:

SmithKline Beecham (Cork) Limited

International Classification:

C07D 405/04
A61K 31/517
C07D 417/04

US Classification:

51426411, 5142662, 51426624, 544279, 544284, 544293

Abstract:

Ditosylate salts of 4-quinazolineamines are described as well as methods of using the same in the treatment of disorde4rs characterized by aberrant erbB family PTK activity.

US Patent:

7442833, Oct 28, 2008

Filed:

Oct 4, 2004

Appl. No.:

10/575038

Inventors:

Dennis Heyer - Durham NC, US
Amarjit Sab Randhawa - Durham NC, US
Vicente Samano - Durham NC, US
John Albert Ray - Durham NC, US
Subba Reddy Katamreddy - Durham NC, US
Michael Tolar Martin - Durham NC, US
Michael Scott McClure - Durham NC, US

Assignee:

SmithKline Beecham Corporation - Philadelphia PA

International Classification:

C07C 63/33
A61K 31/19

US Classification:

562491, 514570

Abstract:

Compounds of formula (I):.

US Patent:

20090137658, May 28, 2009

Filed:

Nov 9, 2007

Appl. No.:

11/937924

Inventors:

Masataka HIKOTA - Shiki-shi, JP
Toru Iijima - Toda-shi, JP
Michael S. McClure - Cary NC, US

International Classification:

A61K 31/40
C07D 295/182

US Classification:

514423, 548540

Abstract:

Besylate salts of trans-4-({2-[(2S)-2-cyano-pyrrolidinyl]-2-oxoethyl}amino)-N,N-dimethylcyclohexanecarboxamide are described as well as methods of using the same in the treatment of disorders characterized by hyperglycemia.

US Patent:

20110224413, Sep 15, 2011

Filed:

Nov 19, 2009

Appl. No.:

13/129496

Inventors:

Michael Tolar Martin - Durham NC, US
Michael S. McClure - Durham NC, US
Vassil Elitzin - Durham NC, US

International Classification:

C07H 17/02
C07D 231/20

US Classification:

536 174, 5483661

Abstract:

Disclosed herein are processes for preparing glucopyranosyloxypyrazole derivatives and pyrazole intermediates of the same. In particular, the present invention relates to glucopyranosyloxypyrazole derivatives having SGLT2 inhibitory activity and processes and intermediates for preparing the same.

US Patent:

20110245496, Oct 6, 2011

Filed:

Jun 9, 2008

Appl. No.:

12/663337

Inventors:

Andrew Simon Craig - Kent, GB
David Malcolm Crowe - Kent, GB
Tim Chien Ting Ho - Kent, GB
Michael S. McClure - Durham NC, US

International Classification:

C07D 405/02

US Classification:

544293

Abstract:

Salts of 4-quinazolineamines are described as well as methods of using the same in the treatment of disorders characterized by aberrant erbB family PTK activity.

US Patent:

20120053330, Mar 1, 2012

Filed:

Apr 29, 2010

Appl. No.:

13/265001

Inventors:

Daniel Edward Patterson - Research Triangle Park NC, US
Michael S. McClure - Research Triangle Park NC, US
Jeremiah David Powers - Research Triangle Park NC, US
Claire Frances Crawford - Hertfordshire, GB
Malcolm Brian Berry - Hertfordshire, GB

International Classification:

C07H 17/02
C07H 15/04
C07H 15/26
C07H 15/203

US Classification:

536 174, 536 182, 536 178, 536 181

Abstract:

Disclosed herein are processes for preparing glucopyranosyloxypyrazole derivatives. In particular, the present invention relates to glucopyranosyloxypyrazole derivatives having SGLT2 inhibitory activity and processes and intermediates for preparing the same.

US Patent:

20210008799, Jan 14, 2021

Filed:

Jul 10, 2020

Appl. No.:

16/926142

Inventors:

- New Haven CT, US
Eman Samma - Woodbridge CT, US
Ammar Samma - St. Petersburg FL, US
Tyler Crain - Oakland CA, US
Aleksander V. Tropp - Old Greenwich CT, US
Michael T. McClure - Shelton CT, US

International Classification:

B29C 64/336
B33Y 30/00
B33Y 80/00
B33Y 50/02
B29C 64/393
B33Y 40/00
B33Y 70/00

Abstract:

A three dimensional printing system which creates a multiple color printed structure which may be e.g. an inflatable likeness. The printing is done with a stretchy material such as silicone and is printed in layers of different color in order to match the designed likeness colors. In preferred embodiments, the 3d printing is done inside a gel suspension with a specialized print head which dispenses silicone in layers of color to produce the final desired color of silicone in the particular locations as determined by the avatar or likeness design.