Michael Anne Packer

US Patent:

D481156, Oct 21, 2003

Filed:

Oct 18, 2002

Appl. No.:

29/169359

Inventors:

Michael Packer - Grandview Heights OH
Jeffrey D. McClow - Newark OH
James M. Pacocha - Westerville OH

Assignee:

Acuity Brands, Inc. - Atlanta GA

International Classification:

2699

US Classification:

D26128

US Patent:

D482816, Nov 25, 2003

Filed:

Oct 18, 2002

Appl. No.:

29/169410

Inventors:

Michael Packer - Grandview Heights OH
Jeffrey D. McClow - Newark OH
James M. Pacocha - Westerville OH

Assignee:

Acuity Brands, Inc. - Atlanta GA

International Classification:

2603

US Classification:

D26 89, D26 61

US Patent:

6971772, Dec 6, 2005

Filed:

Jun 12, 2003

Appl. No.:

10/461190

Inventors:

Yaser S. Abdelsamed - Granville OH, US
Michael Packer - Grandview Heights OH, US

Assignee:

Acuity Brands, Inc. - Atlanta GA

International Classification:

F21V007/00
F21V003/00

US Classification:

362309, 362363, 362308, 362328

Abstract:

Luminaire optical assemblies intended for pole-mounted and similar applications and capable of effective I. E. S. cutoff performance while exhibiting desirable light distributions even with vertically oriented lamping, the invention contemplates in primary embodiments light-transmissive reflector/refractor combinations typically formed of glass, acrylics and the like, uplight shielding and reflector assemblies of a variety of configurations being disposed within the reflector/refractor combinations to produce desired cutoff characteristics while preserving daytime appearance during nocturnal operation. In certain embodiments of the invention, uplight is controlled by the several variations of the uplight shielding and reflector assemblies to cause light-transmissive portions of the reflector/refractor combinations to subtly glow and thus produce a desired appearance while also producing cutoff characteristics necessary to reduce urban sky glow and glare. The luminaire optical assemblies further permit achievement of I. E. S. cutoff with vertical tamping while maximizing efficiency.

US Patent:

20170233708, Aug 17, 2017

Filed:

Oct 22, 2015

Appl. No.:

15/518639

Inventors:

- Cambridge MA, US
Bryan DICKINSON - Chicago IL, US
Michael S. PACKER - Cambridge MA, US
Ahmed Hussein BADREN - Dorchester MA, US

Assignee:

President and Fellows of Harvard College - Cambridge MA

International Classification:

C12N 9/50
C12N 9/12
C12N 15/62
C12N 7/00
C12N 15/86
C12N 15/52

Abstract:

Some aspects of this disclosure provide methods for phage-assisted continuous evolution (PACE) of proteases. Some aspects of this invention provide methods for evaluating and selecting protease inhibitors based on the likelihood of the emergence of resistant proteases as determined by the protease PACE methods provided herein. Some aspects of this disclosure provide strategies, methods, and reagents for protease PACE, including fusion proteins for translating a desired protease activity into a selective advantage for phage particles encoding a protease exhibiting such an activity and improved mutagenesis-promoting expression constructs. Evolved proteases that recognize target cleavage sites which differ from their canonical cleavage site are also provided herein.