Michael L Pierce

US Patent:

D556973, Dec 4, 2007

Filed:

Oct 2, 2006

Appl. No.:

29/249332

Inventors:

Michael G. Pierce - Kennesaw GA, US

International Classification:

9900

US Classification:

D99 29, D99 33

US Patent:

20100297609, Nov 25, 2010

Filed:

Oct 29, 2008

Appl. No.:

12/734102

Inventors:

Robert Lance Wells - Athens GA, US
Ronald C. Orlando - Athens GA, US
Stephen Dalton - Athens GA, US
Kelley W. Moreman - Bishop GA, US
Michael J. Pierce - Athens GA, US
Michael Tiemeyer - Watkinsville GA, US
William S. York - Watkinsville GA, US

Assignee:

University of Georgia Research Foundation, Inc. - Athens GA

International Classification:

C12Q 1/70
C12Q 1/02

US Classification:

435 5, 435 29

Abstract:

The present invention relates to a method of isotopically labeling glycans and in facilitating high throughput quantitative/comparative analysis of glycomic compositions of biological cells. The method is applicable inter alia for identifying differentiated cells and their glycomic characteristics, differentiation conditions, disease and/or therapeutic progression, diagnosing disease states, determining drug activity, establishing manufacturing efficiencies and for determining the half-life of glycans in cells.

US Patent:

20220222401, Jul 14, 2022

Filed:

Jun 10, 2019

Appl. No.:

17/595104

Inventors:

- Houston TX, US
Michael Stephen Pierce - Spring TX, US

International Classification:

G06F 30/27
G06F 30/17

Abstract:

A method includes determining a bit design based on a design criterion, determining a cutter design to be mounted on the bit design at a bit design position based on cutter information, wherein the cutter information is based on a historical cutter performance metric of one or more cutters having the cutter design. The method also includes generating a drill bit model based on the bit design and the cutter design and determining that the drill bit model meets the design criterion.