Michael F Roth

US Patent:

6838081, Jan 4, 2005

Filed:

Apr 2, 1999

Appl. No.:

09/647248

Inventors:

Michael Derek Roth - Los Angeles CA, US
Robert Alan Figlin - Los Angeles CA, US
Sylvia Marie Kiertscher - Los Angeles CA, US
Barbara Jennifer Gitlitz - Los Angeles CA, US

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

A01N 6300
A61K 4500
A61K 3819
C12N 501
C12N 508

US Classification:

424 937, 424 9371, 424 852, 424 857, 435372, 435355, 435366, 435374, 435377, 435384, 435386, 435423

Abstract:

The present invention provides methods for enhancing the development of APC from precursor cells by administering a combination of GM-CSF and IL-4. The precursor cells include: cells contained in peripheral blood, CD cells and precursors in bone marrow. Thus, administration of GM-CSF and IL-4 can be used as a form of cytokine immunotherapy. One embodiment of the present invention involves systemic administration of GM-CSF and IL-4. In this embodiment, APC are required to directly access tumor antigens as they exist in vivo within the patient. A further embodiment of the present invention involves co-administration of a tumor-associated or tumor-specific antigen, with GM-CSF and IL-4, to induce antigen-specific immunity mediated by APC. Yet another embodiment of the present invention describes systemic administration of GM-CSF and IL-4 to achieve reduced tumor burden.

US Patent:

8130260, Mar 6, 2012

Filed:

Aug 26, 2008

Appl. No.:

11/463415

Inventors:

Jerry A. Krill - Fulton MD, US
Nicholas D. Beser - Owings Mills MD, US
David W. Blodgett - Ellicott City MD, US
Michael W. Roth - Columbia MD, US

Assignee:

Johns Hopkins University - Baltimore MD

International Classification:

H04N 7/18

US Classification:

348 53, 348 51, 348 47

Abstract:

Disclosed is a system for a 3-dimensional display that includes at least one eyepiece having first and second eyepiece sockets, having a first display contained in said first eyepiece socket associated with a first eye, two eye cameras mounted such that a first eye camera tracks eye reference points of said first eye and a second eye camera tracks reference points of a second eye, a processor for providing overall control of said at least one eyepiece; a second display; and a main processor; signals are transmitted between said main processor and said at least one eyepiece, wherein said two eye cameras track said reference points, said eyepiece transceiver transmits said reference points to said main processor via said main transceiver, said main processor generates image data based on said reference points and transmits said image data to said displays to produce a 3-dimensional image.

US Patent:

50567403, Oct 15, 1991

Filed:

Sep 22, 1989

Appl. No.:

7/411138

Inventors:

Michael W. Roth - Columbia MD
Glenn E. Mitzel - Clarksville MD

Assignee:

The Johns Hopkins University - Baltimore MD

International Classification:

B64G 110

US Classification:

244158R

Abstract:

The invention is directed to either a satellite or missile deployed to a high altitude location at a desired position above a target. Once at the proper position a drogue chute is deployed to slow reentry and then a high-altitude balloon or paraglider is deployed to maintain the invention above the target area. Once deployed, the invention utilizes onboard sensors to collect target information which is communicated to an over-the-horizon (from the target) receiver.