Michael A Schneider

US Patent:

20010008026, Jul 12, 2001

Filed:

Jun 25, 1998

Appl. No.:

09/104654

Inventors:

MICHAEL D. SCHNEIDER - HOUSTON TX, US
PAUL OVERBEEK - HOUSTON TX, US
PETER FRENKEL - HOUSTON TX, US

International Classification:

A01K067/027

US Classification:

800/008000, 800/009000, 800/014000, 800/018000, 800/003000, 800/021000, 800/022000, 800/025000, 435/455000, 435/462000, 435/463000, 435/465000, 435/325000

Abstract:

The present invention relates to methods and compositions for tissue-restricted gene recombination. In particular, the present invention provides methods and compositions for tissue-restricted gene recombination in post-mitotic cells. The present invention further provides methods for gene recombination in post-mitotic cells comprising the delivery of a Cre recombinase to the target tissue to facilitate recombination in a desired target nucleic acid.

US Patent:

20040082613, Apr 29, 2004

Filed:

Jun 27, 2003

Appl. No.:

10/609073

Inventors:

Michael Schneider - Houston TX, US
Motoaki Sano - Houston TX, US

International Classification:

A61K031/452
A61K031/401

US Classification:

514/320000, 514/423000

Abstract:

The present invention relates generally to the field of cardiology. More particularly, the present invention relates to methods of using inhibitors of cyclin dependent kinase 9 (Cdk9) to treat cardiovascular disease by blunting cardiac hypertrophy.

US Patent:

20040106647, Jun 3, 2004

Filed:

Sep 19, 2003

Appl. No.:

10/665336

Inventors:

Michael Schneider - Houston TX, US
Motoaki Sano - Houston TX, US

International Classification:

A61K031/452

US Classification:

514/320000

Abstract:

The present invention relates generally to the field of cardiology. More particularly, the present invention relates to methods of using inhibitors of cyclin dependent kinase 9 (Cdk9) to treat cardiovascular disease by blunting cardiac hypertrophy.

US Patent:

20040126879, Jul 1, 2004

Filed:

Aug 29, 2003

Appl. No.:

10/651548

Inventors:

Michael Schneider - Houston TX, US
Hidemasa Oh - Houston TX, US
Mark Entman - Houston TX, US

Assignee:

Baylor College of Medicine - Houston TX

International Classification:

C12N005/08

US Classification:

435/372000, 435/366000, 424/093700

Abstract:

The present invention is drawn to compositions and methods of using the same to cardiovascular disease. The compositions of the present invention are cardiac stem cells that are c-kit/CD31/CD38 and express telomerase reverse transcriptase.

US Patent:

20040242461, Dec 2, 2004

Filed:

Apr 8, 2004

Appl. No.:

10/820583

Inventors:

Michael Schneider - Houston TX, US
Hidemasa Oh - Houston TX, US

International Classification:

A61K038/17

US Classification:

514/002000

Abstract:

The present invention embodies methods of modulating telomere repeat-binding factor-2 (TRF2) or cell cycle checkpoint kinase 2 (Chk2) to enhance the survival of a cell. More particularly, the modulators can be used to treat cardiovascular disease by improving the growth and survival of cardiomyocytes.

US Patent:

20050043260, Feb 24, 2005

Filed:

Apr 21, 2004

Appl. No.:

10/828669

Inventors:

Michael Schneider - Houston TX, US
Teruya Nakamura - Houston TX, US

Assignee:

BAYLOR COLLEGE OF MEDICINE - Houston TX

International Classification:

A61K048/00
C12N015/85

US Classification:

514044000, 435455000

Abstract:

The present invention relates to the fields of cell biology, molecular biology, and medicine. More specifically, the invention is directed to generating cardiomyocyte cells from non-cardiomyocyte cells by enhancing the activation of the Wnt/β-catenin signaling pathway. The cardiomyocyte cells that are generated in the present invention are then used as cardiac disease therapy.

US Patent:

49338323, Jun 12, 1990

Filed:

Jun 12, 1989

Appl. No.:

7/365099

Inventors:

Michael E. Schneider - Conroe TX
Richard A. Faulk - Cypress TX

Assignee:

Compaq Computer Corp. - Houston TX

International Classification:

H02M 710

US Classification:

363143

Abstract:

An automatic line monitor for use in conjunction with a power supply for electronic components automatically accommodates either of two voltage ranges. Since the power supply may operate in domestic voltage ranges of about 100 volts or in international voltage ranges of about 120, the automatic line monitor senses and automatically switches to a voltage-doubling mode for the domestic range or a non-voltage-doubling mode for the higher international range. A latch may latch the line monitor in a non-voltage doubling mode once the higher voltage range is sensed. A monitor of a preferred embodiment eliminates almost all of the high-power-handling elements of the switch so that almost all of the operative elements of the switch may be incorporated on a single integrated circuit chip.

US Patent:

56843828, Nov 4, 1997

Filed:

Jul 19, 1996

Appl. No.:

8/684686

Inventors:

Brian C. Fritz - The Woodlands TX
William C. Hallowell - Spring TX
Thomas P. Sawyers - Houston TX
Norman D. Stobert - Spring TX
Robert K. Watts - Houston TX
Michael E. Schneider - Conroe TX

Assignee:

Compaq Computer Corporation - Houston TX

International Classification:

H01M 1044
H01M 1046

US Classification:

320 5

Abstract:

A computer system including circuitry for accurately and economically controlling the charge voltage and charge current at the terminals of its rechargeable battery. During a battery recharge, sensor circuitry coupled to the battery provides accurate data to a battery microcontroller regarding the charge voltage and charge current present at the battery terminals. A battery microcontroller relays this information to a multipurpose microcontroller. The battery microcontroller also provides the desired charging voltage and current as determined by the battery pack's charging algorithm. The multipurpose microcontroller uses the battery status information to program an addressable potentiometer. In turn, the potentiometer generates an adjustment signal that controls the output voltage of the computer's AC adapter. Preferably, the AC adapter is capable of being operated in a constant-power mode.