Formulations comprising one or more epothilones together with a pharmaceutically acceptable carrier, in particular such pharmaceutical compositions suitable for oral administration of an epothilone.
Robert Johnson - Lafayette CA, US Michael Sherrill - Danville CA, US Alison Hannah - Sebastopol CA, US
Assignee:
Kosan Biosciences, Inc., A Delaware Corporation - Hayward CA
International Classification:
A61K031/427
US Classification:
514/365000
Abstract:
Methods to deliver epothilone D to subjects having tumorigenic diseases are provided. In some embodiments, the invention provides methods for treating tumor-bearing subjects with an intravenous infusion of epothilone D at least once about every seven days throughout a delivery period of about twenty-one consecutive day period