Ataxia-Telangiectasia: Genetics, Neuropathology, and Immunology of a Degenerative Disease of Childhood Proceedings of a Conference Held in Solvang, California, January 16-20, 1984
The present invention relates generally to the field of human genetics. Specifically, the present invention relates to the discovery that some alleles of the A-T gene cause susceptibility to cancer, in particular breast cancer. More specifically, the present invention relates to germline mutations in the A-T gene and their use in the diagnosis of predisposition to breast cancer. The invention further relates to somatic mutations in the A-T gene in human breast cancer and their use in the diagnosis and prognosis of human breast cancer.
Predisposition To Breast Cancer By Mutations At The Ataxia-Telangiectasia Genetic Locus
Michael Swift - Scarsdale NY, US Prasanna Athma - Yorktown Heights NY, US Alrong Li - Hastings-on-Hudson NY, US
International Classification:
C12Q001/68 C12P019/34
US Classification:
435/006000, 435/091200
Abstract:
The present invention relates generally to the field of human genetics. Specifically, the present invention relates to the discovery that some alleles of the A-T gene cause susceptibility to cancer, in particular breast cancer. More specifically, the present invention relates to germline mutations in the A-T gene and their use in the diagnosis of predisposition to breast cancer. The invention further relates to somatic mutations in the A-T gene in human breast cancer and their use in the diagnosis and prognosis of human breast cancer.
Dr. Swift graduated from the University of Wisconsin Medical School in 2009. He works in Green Bay, WI and specializes in Internal Medicine. Dr. Swift is affiliated with Bellin Hospital.