Michael W Tsang

US Patent:

6791536, Sep 14, 2004

Filed:

Mar 23, 2001

Appl. No.:

09/815272

Inventors:

Leroy B. Keely - Portola Valley CA
David F. Jones - Redmond WA
David Switzer - Redmond WA
Michael Hin-cheung Tsang - Bellevue WA
William Hong Vong - Seattle WA

Assignee:

Microsoft Corporation - Redmond WA

International Classification:

G09G 500

US Classification:

345173, 345161, 345163, 345168, 345179, 345863

Abstract:

A method and apparatus for simulating at least one gesture of a pointing device such as a mouse. A left click, right click, left drag, right drag, and/or mouse movement may be simulated using a stylus in conjunction with a touch-sensitive display surface. For example, a computer having the display surface may detect whether a stylus is being held down on a touch-sensitive display surface for at least a threshold amount of time. The computer may further detect whether the stylus is then removed from the touch-sensitive display surface after at least the threshold amount of time. Responsive to the stylus being removed, the computer may generate at least one event representing a right mouse button being pressed.

US Patent:

7022672, Apr 4, 2006

Filed:

Nov 30, 2001

Appl. No.:

09/996588

Inventors:

Glenn J. Dorin - San Rafael CA, US
Bo H. Arve - Cary NC, US
Gregory L. Pattison - Oakland CA, US
Robert F. Halenbeck - San Rafael CA, US
Kirk Johnson - Moraga CA, US
Bao-Lu Chen - San Ramon CA, US
Maninder S. Hoba - Danville CA, US
Hassan Madani - Seattle WA, US
Michael Tsang - San Francisco CA, US
Mark E. Gustafson - St. Charles MI, US
Gary S. Bild - Chesterfield MI, US
Gary V. Johnson - St. Charles MI, US

Assignee:

Chiron Corporation - Emeryville CA
G. D. Searle, LLC - St. Louis MO

International Classification:

A61K 38/00
C07K 14/00

US Classification:

514 12, 514 2, 514 8, 514 21, 514970, 514973, 530350, 530395

Abstract:

A method of modifying protein solubility employs polyionic polymers. These facilitate the solubilization, formulation, purification and refolding of proteins especially incorrectly folded proteins and aggregated proteins. Compositions are described that are suitable for formulating TFPI. The compositions allow preparation of pharmaceutically acceptable compositions of TFPI at concentrations above 0. 2 mg/mL and above 10 mg/mL.

US Patent:

20080281084, Nov 13, 2008

Filed:

Apr 5, 2007

Appl. No.:

11/697188

Inventors:

Glenn J. Dorin - San Rafael CA, US
Bo H. Arve - Cary NC, US
Gregory L. Pattison - Oakland CA, US
Robert F. Halenbeck - San Rafael CA, US
Kirk Johnson - Moraga CA, US
Bao-Lu Chen - San Ramon CA, US
Maninder S. Hora - Danville CA, US
Hassan Madani - Seattle WA, US
Michael Tsang - San Francisco CA, US
Mark E. Gustafson - St. Charles MI, US
Gary S. Bild - Chesterfield MI, US
Gary V. Johnson - St. Charles MI, US

Assignee:

Novartis Vaccines and Diagnostics, Inc. - Emeryville CA
G. D. Searle LLC - New York NY

International Classification:

C07K 14/47

US Classification:

530395

Abstract:

Compositions are described that are suitable for formulating TFPI. Solubilizers and stabilizers facilitate the preparation of pharmaceutically acceptable compositions of TFPI at various concentrations.

US Patent:

63233266, Nov 27, 2001

Filed:

Jun 11, 1999

Appl. No.:

8/973211

Inventors:

Glenn J. Dorin - San Rafael CA
Bo H. Arve - Cary NC
Gregory L. Pattison - Oakland CA
Robert F Halenbeck - San Rafael CA
Kirk Johnson - Moraga CA
Bao-Lu Chen - San Ramon CA
Maninder S. Hoba - Danville CA
Hassan Madani - Seattle WA
Michael Tsang - San Francisco CA
Mark E. Gustafson - St. Charles MO
Gary S. Bild - Chesterfield MO
Gary V. Johnson - Charles MO

Assignee:

Chiron Corporation - Emeryville CA
G. D. Searle & Co. - Skokie IL

International Classification:

A23J 100

US Classification:

530412

Abstract:

A method of modifying protein solubility employs polyionic polymers. These facilitate the solubilization, formulation, purification and refolding of proteins especially incorrectly folded proteins and aggregated proteins. Compositions are described that are suitable for formulating TFPI. The compositions allow preparation of pharmaceutically acceptable compositions of TFPI at concentrations above 0. 2 mg/mL and above 10 mg/mL.

US Patent:

63198967, Nov 20, 2001

Filed:

Nov 18, 1999

Appl. No.:

9/443098

Inventors:

Glenn J. Dorin - San Rafael CA
Bo H. Arve - Cary NC
Gregory L. Pattison - Oakland CA
Robert F. Halenbeck - San Rafael CA
Kirk Johnson - Moraga CA
Bao-Lu Chen - San Ramon CA
Maninder S. Hora - Danville CA
Hassan Madani - Seattle WA
Michael Tsang - San Francisco CA
Mark E. Gustafson - St. Charles MO
Gary S. Bild - Chesterfield MO
Gary V. Johnson - Charles MO

Assignee:

Chiron Corporation - Emeryville CA
G.D. Searle & Co. - Skokie IL

International Classification:

A61K 3816
A01N 3718

US Classification:

514 8

Abstract:

A method of modifying protein solubility employs polyionic polymers. These facilitate the solubilization, formulation, purification and refolding of proteins especially incorrectly folded proteins and aggregated proteins. Compositions are described that are suitable for formulating TFPI. The compositions allow preparation of pharmaceutically acceptable compositions of TFPI at concentrations above 0. 2 mg/mL and above 10 mg/mL.