Michael G Webster

US Patent:

20110306146, Dec 15, 2011

Filed:

Sep 29, 2009

Appl. No.:

13/063412

Inventors:

Harbaksh Sidhu - Allison Park PA, US
Ziqiang Wang - Lansdale PA, US
Michael Webster - Gibsonia PA, US

Assignee:

THAR INSTRUMENTS, INC. - Pittsburg PA

International Classification:

G01N 21/76
G01N 30/02

US Classification:

436172, 422 62

Abstract:

The invention provides an apparatus for supercritical fluid chromatography. The apparatus comprises a binary pump; an autosampler; a sampling valve; a first and second port switching valve; a first and second manifold; two or more channels, each having a check valve assembly, a separation column and one or more detectors operatively connected thereon; and a backpressure regulator. The apparatus also includes computer software and hardware to control distribution of fluid through the apparatus, including switching between a multi-channel mode or a single channel ode; 2) analyze data collected by the one or more detectors; and 3) optimize separation of analytes by controlling solvent combinations, concentration gradients, pressure and temperature. The apparatus excludes additional backpressure regulators or pumps on individual channels. Also provided is a method of screening a sample, using supercritical chromatography, using the above apparatus, where multiple samples can be screened simultaneously with parallel processing.

US Patent:

20190282923, Sep 19, 2019

Filed:

Mar 14, 2019

Appl. No.:

16/353194

Inventors:

- Milford MA, US
Michael Webster - Gibsonia PA, US
Andrew Sulik - Pittsburgh PA, US
Steven Stricko - Trafford PA, US
Andrew Aubin - Taunton MA, US
Christopher J. Hudalla - Milford MA, US

Assignee:

Waters Technologies Corporation - Milford MA

International Classification:

B01D 11/02
B01D 21/26
B01D 50/00

Abstract:

The present disclosure relates to methodologies, systems, and devices for discretely collecting extracts from an extract collection container of a CO-based extraction system. A removable liner can be placed within the extract collection container such that the extract is collected within the removable liner, which can be removed or collected at discrete times. The removable liner can be hung from an extract fluid inlet tube or attached to an internal sidewall of the extract collection container.

US Patent:

20190282926, Sep 19, 2019

Filed:

Mar 13, 2019

Appl. No.:

16/351753

Inventors:

- Milford MA, US
Glenn Chesney - Monroeville PA, US
Andrew Sulik - Pittsburgh PA, US
Michael Webster - Gibsonia PA, US
Edward J. Ognibene - Belmont MA, US
Brendan McKinley - Malvern PA, US
David Sauers - Rural Ridge PA, US

Assignee:

Waters Technologies Corporation - Milford MA

International Classification:

B01D 15/40
G01N 30/02

Abstract:

The present disclosure relates to methodologies, systems, and devices for compressing COfor recycling within a CO-based chromatography or extraction system. A bellows pump can receive COin a gaseous state and can compress the COinto a liquid or partially liquid-vapor state using hydraulic compression. Once compressed, the liquid or liquid-vapor COcan be recycled within the CO-based chromatography or extraction system.

US Patent:

20190282928, Sep 19, 2019

Filed:

Mar 13, 2019

Appl. No.:

16/351748

Inventors:

- Milford MA, US
Michael Webster - Gibsonia PA, US
Pratik Gandhi - Mars PA, US
Steven Stricko - Trafford PA, US
Darcy Shave - Blackstone MA, US
Andrew Aubin - Taunton MA, US
Joseph D. Antocci - Leominster MA, US
Richard Skinner - Mendon MA, US
Bryan Cumming - Lunenburg MA, US
Ziqiang Wang - Lansdale PA, US

Assignee:

Waters Technologies Corporation - Milford MA

International Classification:

B01D 17/02
B01D 11/04

Abstract:

The present disclosure relates to methodologies, systems, and devices for collecting extract in a CO-based extraction system. A diffuser can be used, attached to one end of an extraction tube, in order to depressurize the COand extract mixture as it exits the diffuser and enters the extraction collection container. A splash guard can also be attached to the extraction tube in order to block any splashing of extract while COis allowed to vent from the extraction collection container.