Michael A Wolf

US Patent:

8095210, Jan 10, 2012

Filed:

Jan 19, 2007

Appl. No.:

11/625230

Inventors:

Joel W. Burdick - Pasadena CA, US
Jorge G. Cham - Pasadena CA, US
Zoran Nenadic - Irvine CA, US
Edward A. Branchaud - Lawrence MA, US
Michael T. Wolf - Pasadena CA, US
Richard A. Andersen - La Canada Flintridge CA, US

Assignee:

California Institute of Technology - Pasadena CA

International Classification:

A61B 5/04

US Classification:

600544, 600545

Abstract:

The present invention relates to systems and methods for controlling neural prosthetic devices and electrophysiological recording equipment, and for using the same in clinical operation. Various embodiments of the invention are directed to an algorithm for autonomously isolating and maintaining neural action potential recordings. The algorithm may be used in connection with a neural interface microdrive capable of positioning electrodes to record signals from active neurons.

US Patent:

20120219613, Aug 30, 2012

Filed:

Jun 18, 2009

Appl. No.:

13/000310

Inventors:

Benhur Lee - Los Angeles CA, US
Michael E. Jung - Los Angeles CA, US
Michael C. Wolf - Los Angeles CA, US
Tinghu Zhang - Los Angeles CA, US

Assignee:

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - Oakland CA

International Classification:

A61K 31/427
A61P 31/18
C07D 495/04
A61P 31/16
A61K 9/127
C07D 417/06
A61P 31/14
A61P 31/22

US Classification:

424450, 514369, 548183

Abstract:

Provided herein are a series of arylmethylidene rhodanine derivatives having broad-spectrum antiviral activity against enveloped viruses, including but not limited to filoviruses, poxviruses, arenaviruses, bunyaviruses, paramyxoviruses, flaviviruses, influenza A, and HIV-1. The compounds act via a novel mechanism to disrupt viral membranes and inhibit viral attachment, fusion, and/or entry into host cells. The membrane disrupting activity of the compounds is selective for viral membranes relative to other biological membranes, making the compounds non-toxic to cells and host subjects.

US Patent:

20120265380, Oct 18, 2012

Filed:

Apr 13, 2012

Appl. No.:

13/446899

Inventors:

Yoshiaki Kuwata - Los Angeles CA, US
Michael T. Wolf - Los Angeles CA, US
Dimitri V. Zarzhitsky - La Canada Flintridge CA, US
Hrand Aghazarian - La Crescenta CA, US
Terrance L. Huntsberger - Altadena CA, US
Andrew B. Howard - Los Angeles CA, US

Assignee:

California Institute of Technology - Pasadena CA

International Classification:

G05D 1/02

US Classification:

701 21

Abstract:

Systems and methods for operating autonomous waterborne vessels in a safe manner. The systems include hardware for identifying the locations and motions of other vessels, as well as the locations of stationary objects that represent navigation hazards. By applying a computational method that uses a maritime navigation algorithm for avoiding hazards and obeying COLREGS using Velocity Obstacles to the data obtained, the autonomous vessel computes a safe and effective path to be followed in order to accomplish a desired navigational end result, while operating in a manner so as to avoid hazards and to maintain compliance with standard navigational procedures defined by international agreement. The systems and methods have been successfully demonstrated on water with radar and stereo cameras as the perception sensors, and integrated with a higher level planner for trailing a maneuvering target.

US Patent:

20130028966, Jan 31, 2013

Filed:

Apr 13, 2011

Appl. No.:

13/640732

Inventors:

Benhur Lee - Los Angeles CA, US
Michael E. Jung - Los Angeles CA, US
Jihye Lee - Los Angeles CA, US
Frederic Vigant - Hollywood CA, US
Peter J. Bradley - Los Angeles CA, US
Michael C. Wolf - Washington DC, US
Bettina E. Hajagos - Corona Del Mar CA, US

Assignee:

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - Oakland CA

International Classification:

A61K 31/429
A61K 31/422
A61K 31/4178
C07D 417/06
A61P 31/22
C07D 405/06
A61P 31/12
A61P 31/18
A61P 33/00
A61P 31/14
A61K 9/127
C07D 413/06

US Classification:

424450, 514369, 514376, 514389, 548183, 548226, 5483161

Abstract:

The invention provides compounds represented by the formulae: (I) and (II) where the compounds are useful in treating, for example, viral and/or parasitic infections. Also provided are pharmaceutical compositions comprising the compounds and methods of treatment using the compounds.

US Patent:

20170259428, Sep 14, 2017

Filed:

Feb 28, 2017

Appl. No.:

15/445693

Inventors:

- Pasadena CA, US
Jaakko T. KARRAS - PASADENA CA, US
Michael T. WOLF - LA CRESCENTA CA, US
Adrian STOICA - PASADENA CA, US

International Classification:

B25J 9/16
G06N 99/00
B25J 13/08
A61B 5/0492
A61B 5/00

Abstract:

A sleeve worn on an arm allows detection of gestures by an array of sensors. Electromyography, inertial, and magnetic field sensors provide data that is processed to categorize gestures and translate the gestures into commands for robotic systems. Machine learning allows training of gestures to increase accuracy of detection for different users.

US Patent:

20160207908, Jul 21, 2016

Filed:

Sep 16, 2015

Appl. No.:

14/856329

Inventors:

- Oakland CA, US
Michael E. Jung - Los Angeles CA, US
Jihye Lee - Los Angeles CA, US
Frederic Vigant - Hollywood CA, US
Peter J. Bradley - Los Angeles CA, US
Michael C. Wolf - Washington DC, US
Bettina E. Hajagos - Corona Del Mar CA, US

International Classification:

C07D 413/06
A61K 9/00
C07D 405/06
A61K 9/127

Abstract:

The invention provides compounds represented by the formulae: (I) and (II) where the compounds are useful in treating, for example, viral and/or parasitic infections. Also provided are pharmaceutical compositions comprising the compounds and methods of treatment using the compounds.