Min J Li

US Patent:

20200114352, Apr 16, 2020

Filed:

Oct 7, 2019

Appl. No.:

16/594848

Inventors:

- Ames IA, US
Min Li - Ames IA, US

International Classification:

B01L 3/00
B03C 5/00
C12N 13/00

Abstract:

A microfluidic device comprising one or more fluidic microchannels and one or more arrays of cell assay units is disclosed. Each cell assay unit in turn comprises at one bipolar electrode, micropocket, reaction chamber, and leak channel. In some embodiments, the cell assay unit further comprises two or more split BPEs inside the reaction chamber. The disclosed microfluidic device can be used to separate cells, especially rare cells, from its biological matrix and then analyze the isolated cell inside the reaction chamber. The disclosed device can isolate and analyze cells in a high-throughput fashion and without any modification or labelling to the cells. Cells isolated using the disclosed devices does not lose their vitality.

US Patent:

20180111124, Apr 26, 2018

Filed:

Oct 25, 2017

Appl. No.:

15/793587

Inventors:

- Ames IA, US
Min Li - Ames IA, US

International Classification:

B01L 3/00
C12M 1/00
G01N 15/14

Abstract:

A microfluidic device comprising one or more fluidic microchannels and one or more arrays of wireless bipolar electrodes is disclosed. The disclosed microfluidic device can be used to separate cells, especially rare cells, from its biological matrix. The disclosed device can isolate cells in a high-throughput fashion and without any modification or labelling to the cells. Cells isolated using the disclosed devices does not lose their vitality.