Ming Chen

US Patent:

8048886, Nov 1, 2011

Filed:

Dec 7, 2007

Appl. No.:

12/518184

Inventors:

Zhuoliang Chen - Cambridge MA, US
Run-Ming David Wang - Cambridge MA, US
Ming Chen - Cambridge MA, US
Christopher Sean Straub - Cambridge MA, US
Leigh Zawel - Cambridge MA, US

Assignee:

Novartis AG - Basel

International Classification:

A61K 31/4965

US Classification:

51425506, 544120, 544333, 544407, 548125, 548202, 548254, 548255, 548444, 548503, 548518, 549398, 585 26

Abstract:

The present invention relates to novel IAP inhibitor compounds of formula I:.

US Patent:

8058272, Nov 15, 2011

Filed:

Dec 7, 2007

Appl. No.:

12/518195

Inventors:

Zhuoliang Chen - Cambridge MA, US
Run-Ming David Wang - Cambridge MA, US
Ming Chen - Cambridge MA, US
Christopher Sean Straub - Cambridge MA, US
Leigh Zawel - Cambridge MA, US

Assignee:

Novartis AG - Basel

International Classification:

C07D 401/02
A61K 31/44

US Classification:

5142372, 514312, 514333, 514334, 514349, 544131, 544333, 546152, 546256, 546261, 5462681, 546297

Abstract:

The present disclosure relates to XIAP inhibitor compound of the formula I:.

US Patent:

8044209, Oct 25, 2011

Filed:

Oct 10, 2007

Appl. No.:

12/445435

Inventors:

Mark G. Charest - Cambridge MA, US
Christine Hiu-Tung Chen - Waltham MA, US
Ming Chen - Jupiter FL, US
Zhuoliang Chen - Belmont MA, US
Miao Dai - Dover MA, US
Feng He - Arlington MA, US
Huangshu Lei - Durham NC, US
Christopher Sean Straub - Stow MA, US
Run-Ming David Wang - Cambridge MA, US
Leigh Zawel - Hingham MA, US

Assignee:

Novartis AG - Basel

International Classification:

A61K 31/4439
C07D 405/14
C07D 401/14

US Classification:

5462791, 5462774, 5462734, 435375

Abstract:

The present invention relates to novel IAP inhibitor compounds of: Formula (I).

US Patent:

20070155727, Jul 5, 2007

Filed:

Dec 22, 2006

Appl. No.:

11/644822

Inventors:

Ming Chen - Somerville MA, US
Emmanuel Claret - Besancon, FR
Arwed Cleve - Berlin, DE
David Davey - El Sobrante CA, US
William Guilford - Belmont CA, US
Thomas Kirkland - Atascadero CA, US
Monica Kochanny - Benicia CA, US
Amy Liang - Vallejo CA, US
David Light - San Mateo CA, US
John Parkinson - Martinez CA, US
David Vogel - Richmond CA, US
Guo Wei - San Ramon CA, US
Bin Ye - Moraga CA, US
Hong Ye - Richmond CA, US

Assignee:

Schering Aktiengessellschaft - Berlin

International Classification:

A61K 31/551
A61K 31/407
C07D 487/02
C07D 243/08

US Classification:

514218000, 514412000, 540575000, 548453000

Abstract:

This invention is directed to compounds of formula (I): where r, q, R, R, R, R, R, R, R, R, R, R, R, R, R, R, Rand Rare described herein, or pharmaceutically acceptable salts, solvates, polymorphs, ammonium ions, N-oxides or prodrugs thereof; which are leukotriene Ahydrolase inhibitors and which are therefore useful in treating inflammatory disorders. Pharmaceutical compositions comprising the compounds of the invention and methods of using and preparing the compounds of the invention are also disclosed.

US Patent:

20110319614, Dec 29, 2011

Filed:

Sep 8, 2011

Appl. No.:

13/228221

Inventors:

Zhuoliang CHEN - Belmont MA, US
Run-Ming David WANG - Cambridge MA, US
Ming CHEN - Jupiter FL, US
Christopher Sean STRAUB - Stow MA, US
Leigh ZAWEL - Hingham MA, US

Assignee:

NOVARTIS AG - Basel

International Classification:

C07D 241/18
C07D 401/06
C07D 403/14
C07D 401/14
C07D 413/14
C07D 239/36
C07D 413/10

US Classification:

544120, 544408, 544319, 544405, 544123, 544296, 544295

Abstract:

The present invention relates to novel IAP inhibitor compounds of formula I:

US Patent:

20130091520, Apr 11, 2013

Filed:

Oct 11, 2011

Appl. No.:

13/270468

Inventors:

Ming Chen - Bedford MA, US

Assignee:

VERIZON PATENT AND LICENSING INC. - Basking Ridge NJ

International Classification:

H04N 21/258

US Classification:

725 34

Abstract:

A distribution system of programs and ads includes transmitting one or more ad channels to user devices. An ad channel includes ads and ratings that indicate a likelihood of interest of a user for an ad. The ratings are calculated based on ad profiles and user profiles. A user device selects ads to play during an ad insertion period of a program based on the rating.

US Patent:

20130322674, Dec 5, 2013

Filed:

May 31, 2012

Appl. No.:

13/485134

Inventors:

Dahai Ren - Lincoln MA, US
Ming Chen - Bedford MA, US

Assignee:

Verizon Patent and Licensing Inc. - Basking Ridge NJ

International Classification:

H04R 1/20

US Classification:

381337

Abstract:

An approach for enabling audio content to be directed to a select user from any location within a premises is described. A directional sound module determines a signal strength of a mobile device associated with a user relative to a wireless access point located within a premises and correlates the signal strength to a reference location within the premises based on predetermined wireless fingerprint information. The directional sound module then determines a direction to transmit an ultrasound signal for conveying audible sound to the user.

US Patent:

20130325942, Dec 5, 2013

Filed:

May 30, 2012

Appl. No.:

13/483329

Inventors:

Ming Chen - Bedford MA, US
Xiwang Yang - Brooklyn NY, US
Yong Liu - Brooklyn NY, US
Lei Zhang - Frisco TX, US

Assignee:

VERIZON PATENT AND LICENSING INC. - Basking Ridge NJ

International Classification:

G06F 15/16

US Classification:

709204

Abstract:

A device includes a processor. The processor is configured to determine a hit time for each of a plurality of content items based on at least one of users' history of access to the content items on content distribution clusters in a content distribution network, the users' past ratings of the content items, and social network information associated with the users. The hit time of a content item indicates a number of times that the content item is likely to be accessed by the users. The processor is further configured to compute caching priorities of the content items based on a caching policy of the device and the determined hit times, and initiate a redistribution, over a network, of the plurality of content items over the content distribution clusters of the content distribution network based on the caching priorities.