Ming Z Chen

US Patent:

8044209, Oct 25, 2011

Filed:

Oct 10, 2007

Appl. No.:

12/445435

Inventors:

Mark G. Charest - Cambridge MA, US
Christine Hiu-Tung Chen - Waltham MA, US
Ming Chen - Jupiter FL, US
Zhuoliang Chen - Belmont MA, US
Miao Dai - Dover MA, US
Feng He - Arlington MA, US
Huangshu Lei - Durham NC, US
Christopher Sean Straub - Stow MA, US
Run-Ming David Wang - Cambridge MA, US
Leigh Zawel - Hingham MA, US

Assignee:

Novartis AG - Basel

International Classification:

A61K 31/4439
C07D 405/14
C07D 401/14

US Classification:

5462791, 5462774, 5462734, 435375

Abstract:

The present invention relates to novel IAP inhibitor compounds of: Formula (I).

US Patent:

20110319614, Dec 29, 2011

Filed:

Sep 8, 2011

Appl. No.:

13/228221

Inventors:

Zhuoliang CHEN - Belmont MA, US
Run-Ming David WANG - Cambridge MA, US
Ming CHEN - Jupiter FL, US
Christopher Sean STRAUB - Stow MA, US
Leigh ZAWEL - Hingham MA, US

Assignee:

NOVARTIS AG - Basel

International Classification:

C07D 241/18
C07D 401/06
C07D 403/14
C07D 401/14
C07D 413/14
C07D 239/36
C07D 413/10

US Classification:

544120, 544408, 544319, 544405, 544123, 544296, 544295

Abstract:

The present invention relates to novel IAP inhibitor compounds of formula I:

US Patent:

20220348555, Nov 3, 2022

Filed:

Apr 12, 2021

Appl. No.:

17/227819

Inventors:

- New York NY, US
Shawn Cabral - Groton CT, US
Ming Zhu Chen - Mystic CT, US
Chulho Choi - Mystic CT, US
Robert Lee Dow - Quincy MA, US
Olugbeminiyi Omezia Fadeyi - Harvard MA, US
David Hepworth - Concord MA, US
Jayasankar Jasti - East Lyme CT, US
Lyn Howard Jones - Winchester MA, US
Arjun Venkat Narayanan - Cambridge MA, US
Mihir Dineshkumar Parikh - East Greenwich RI, US
David Walter Piotrowski - Waterford CT, US
Lee Richard Roberts - Belmont MA, US
Hatice Gizem Yayla - Mystic CT, US

Assignee:

Pfizer Inc. - New York NY

International Classification:

C07D 401/14
A61P 7/06
C07D 471/04

Abstract:

The invention relates to pyrazole derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes.More particularly the invention relates to HbS modulators of formula (I)or tautomers thereof, or pharmaceutically acceptable salts of said modulators or tautomers thereof, wherein X, Y, Rand Rare as defined in the description.HbS modulators are potentially useful in the treatment of a wide range of disorders, including sickle cell disease (SCD).

US Patent:

20200172512, Jun 4, 2020

Filed:

Nov 26, 2019

Appl. No.:

16/695709

Inventors:

- New York NY, US
Arjun Venkat Narayanan - Cambridge MA, US
Chulho Choi - Mystic CT, US
David Hepworth - Concord MA, US
David Walter Piotrowski - Waterford CT, US
Hatice Gizem Yayla - Mystic CT, US
Jayasankar Jasti - East Lyme CT, US
Lee Richard Roberts - Belmont MA, US
Lyn Howard Jones - Winchester MA, US
Mihir Dineshkumar Parikh - East Greenwich RI, US
Ming Zhu Chen - Mystic CT, US
Olugbeminiyi Omezia Fadeyi - Harvard MA, US
Robert Lee Dow - Quincy MA, US
Shawn Cabral - Groton CT, US

Assignee:

Pfizer Inc. - New York NY

International Classification:

C07D 401/14
C07D 471/04
A61P 7/06

Abstract:

The invention relates to pyrazole derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes.More particularly the invention relates to HbS modulators of formula (I)or tautomers thereof, or pharmaceutically acceptable salts of said modulators or tautomers thereof, wherein X, Y, Rand Rare as defined in the description.HbS modulators are potentially useful in the treatment of a wide range of disorders, including sickle cell disease (SCD).

US Patent:

20160350573, Dec 1, 2016

Filed:

Mar 5, 2015

Appl. No.:

15/115058

Inventors:

- San Diego CA, US
John Keith Schneider - Williamsville NY, US
Ashish Hinger - Sunnyvale CA, US
Ranjith Ranganathan - San Jose CA, US
Kostadin Dimitrov Djordjev - San Jose CA, US
Stephen Michael Gojevic - Lockport NY, US
David William Burns - San Jose CA, US
Nao Sugawara Chuei - San Diego CA, US
Eliza Yingzi Du - Cupertino CA, US
Ming Yu Chen - Santa Clara CA, US
Kwokleung Chan - San Diego CA, US
Jin Gu - Santa Clara CA, US
Esra Vural - Santa Clara CA, US

Assignee:

Qualcomm Incorporated - San Diego CA

International Classification:

G06K 9/00
G06K 9/62
G01S 15/89

Abstract:

Systems and methods for multi-spectral ultrasonic imaging are disclosed. In one embodiment, a finger is scanned at a plurality of ultrasonic scan frequencies. Each scan frequency provides an image information set describing a plurality of pixels of the finger including a signal-strength indicating an amount of energy reflected from a surface of a platen on which a finger is provided. For each of the pixels, the pixel output value corresponding to each of the scan frequencies is combined to produce a combined pixel out put value for each pixel. Systems and methods for improving the data capture of multi-spectral ultrasonic imaging are also disclosed.