Mohammad K Aslam

US Patent:

6420606, Jul 16, 2002

Filed:

Jun 23, 2000

Appl. No.:

09/602772

Inventors:

Mohammad Aslam - Bridgewater NJ
Patrick MacManus - Morristown NJ
Margaret Cullen - Morristown NJ

Assignee:

Honeywell International Inc. - Morristown NJ

International Classification:

C07C21100

US Classification:

564305, 564336, 564342, 564343

Abstract:

Disclosed are methods of producing of alkoxy arylamine compounds which find particular use in the syntheses of pharmaceutical drug. The alkoxy arylamine compounds generally have the formula: wherein Ar is an unsubstituted or substituted aromatic group, and R is an unsubstituted or substituted alkyl or aryl group. The methods comprise generally, the steps of (a) alkylating a protected-amino arylalcohol to form a protected-amino arylether; and (b) deprotecting said protected-amino arylether to form an alkoxy arylamine compound.

US Patent:

20080255103, Oct 16, 2008

Filed:

Apr 12, 2007

Appl. No.:

11/786715

Inventors:

Mohammad Aslam - Porter TX, US
J. Rao Nulu - Austin TX, US
Terry Ballay - San Marcos TX, US
Matthew S. Ballay - Kyle TX, US

Assignee:

Ballay Pharmaceuticals, Inc. - Wimberley TX

International Classification:

A61K 31/54
A61P 1/08
A61P 37/00

US Classification:

5142248

Abstract:

A topical pharmaceutical preparation suitable for use as an antihistamine or anti-nausea drug comprises an emu oil gel base and a therapeutic amount of promethazine.HCl. The preparation may further comprise an antioxidant. The preparation is preferably packaged as a single unit dose. A method for preparing the topical pharmaceutical preparation comprises the steps of combining a clear gel with an emu oil mixture and adding a therapeutic amount of promethazine.HCl solution.

US Patent:

48682560, Sep 19, 1989

Filed:

Aug 2, 1988

Appl. No.:

7/226258

Inventors:

Mohammad Aslam - Corpus Christi TX
Richard Vicari - Chatham Township, Morris County NJ
Ralph Dammel - Mainz-Bretzenheim, DE
Juergen Lingnau - Mainz-Laubenheim, DE
Karl-Friedrich Doessel - Wiesbaden, DE

Assignee:

Hoechst Celanese - Somerville NJ

International Classification:

C08F 818

US Classification:

526 75

Abstract:

The present invention relates to a process for the production of 3-mono or 3,5-disubstituted-4-acetoxystyrene wherein the 3- or 3,5-substitution is independently C. sub. 1 to C. sub. 10 alkyl, chlorine, bromine, iodine, --NO. sub. 2, --NH. sub. 2, or --SO. sub. 3 H, a process for its polymerization, hydrolysis, and use in a variety of compositions.

US Patent:

50415719, Aug 20, 1991

Filed:

Mar 29, 1990

Appl. No.:

7/503490

Inventors:

Mohammad Aslam - Corpus Christi TX
Hans-Joachim Metz - Bensheim, DE

Assignee:

Hoechst Celanese Corporation - Somerville NJ

International Classification:

C07C 5018

US Classification:

552268

Abstract:

A process for the preparation of anthraquinone compounds comprises reaction of phthalic anhydride with a benzene derivative in a reaction mixture containing HF and BF. sub. 3 as catalyst at a first temperature up to about 30. degree. C. and, subsequently, at an elevated temperature.

US Patent:

51515407, Sep 29, 1992

Filed:

Nov 26, 1986

Appl. No.:

6/935461

Inventors:

Mohammad Aslam - Corpus Christi TX
Kenneth G. Davenport - Corpus Christi TX

Assignee:

Hoechst Celanese Corporation - Somerville NJ

International Classification:

C07C33300
C07C21100

US Classification:

558232

Abstract:

A method is provided for preparing N-acylaminothiophenols, e. g. , N-acetyl-para-aminothiophenol, or aminothiophenols, e. g. , para-aminothiophenol, or N,S-diacylaminothiophenols, e. g. , N,S-diacetyl-para-aminothiophenol, by reacting any of certain sulfur-containing ketones, viz. , an S-(acylaryl) N,N-di(organo)thiocarbamate, e. g. , S-(4'-acetophenyl)-N,N-dimethylthiocarbamate, an acylthiophenol acylate ester, e. g. , 4-acetothiophenol acetate, or a free acylthiophenol, e. g. , 4-acetothiophenol with hydroxylamine or a hydroxylamine salt, to form the oxime of the ketone, subjecting the oxime to a Beckmann rearrangement in the presence of a catalyst to form an S-(N-acyl-aminoaryl) N,N-di(organo)thiocarbamate, e. g. , S-(N-acetyl-para-aminophenyl) N,N-dimethylthiocarbamate, an N,S-diacylaminothiophenol, e. g. , N,S-diacetyl-paraaminothiophenol, or an N-acyl aminothiophenol, e. g.

US Patent:

53449800, Sep 6, 1994

Filed:

Nov 23, 1993

Appl. No.:

8/157486

Inventors:

Mohammad Aslam - Corpus Christi TX
William Basinger - Decatur GA

Assignee:

Hoechst Celanese Corp. - Somerville NJ

International Classification:

C07C 1102

US Classification:

564269

Abstract:

Novel 4-substituted acetophenone anils and methods for preparing 1,3,5-tris(4'-hydroxyphenyl)benzenes from 4-substituted acetophenones such as 4-hydroxyacetophenones or, from substituted 4-hydroxyacetophenone-anils such as 4-hydroxyacetophenone-anil by reacting the 4-substituted acetophenone or corresponding anil with an aniline derivative.

US Patent:

59773693, Nov 2, 1999

Filed:

Dec 28, 1995

Appl. No.:

8/579758

Inventors:

Ranjit Desai - Kendall Park NJ
Daniel Alfonso Aguilar - Corpus Christi TX
Mohammad Aslam - Corpus Christi TX
Nicholas Gallegos - Corpus Christi TX

Assignee:

Napp Technologies, Inc. - Saddle Brook NJ

International Classification:

C07D21186

US Classification:

546321

Abstract:

A novel process is disclosed for the preparation of dihydropyridine compounds and derivatives thereof, and more particularly felodipine. The process to prepare felodipine involves a two step procedure condensing 2,3-dichlorobenzaldehyde with methyl acetoacetate in the presence of a catalyst system. The resultant benzylidine intermediate is sequentially reacted with ethyl aminocrotonate to provide felodipine. The novelty of the present invention resides in part on (1) a new catalyst system not previously disclosed for the preparation of felodipine, (2) the absence of acid(s), (3) the control of reaction conditions to yield lower amounts of unreacted aldehyde compared to known reactions, (4) a simplified purification process, and (5) formation of negligible quantities of symmetrical diester byproducts.

US Patent:

57262950, Mar 10, 1998

Filed:

Mar 7, 1997

Appl. No.:

8/813097

Inventors:

Mohammad Aslam - Corpus Christi TX
Michael T. Sheehan - Corpus Christi TX
Debasish Kuila - Corpus Christi TX

Assignee:

Hoechst Celanese Corp. - Somerville NJ

International Classification:

C07D31120
C07D33506

US Classification:

534556

Abstract:

A new class of 3,4-dihydrocoumarin derivatives which are useful as photoactive compounds in a wide variety of applications including photoresists and other opto-electronic applications are disclosed and claimed. Preferred embodiments include ether, ester, carbonate, and sulfonate derivatives of 5-hydroxy, 6-hydroxy, and 7-hydroxy-3-diazo-4-oxo-3,4-dihydrocoumarins. These compounds exhibit very high photosensitivity in the deep ultraviolet (DUV) region (ca. 250 nm), and therefore, are useful as photoactive compounds in DUV photoresist formulations.