Monica Marie Moya

US Patent:

20120083425, Apr 5, 2012

Filed:

Oct 5, 2011

Appl. No.:

13/253820

Inventors:

Steven C. George - Irvine CA, US
Christopher C.W. Hughes - Irvine CA, US
Abraham P. Lee - Irvine CA, US
Monica Moya - Irvine CA, US
Yu-Hsiang Hsu - Pasadena CA, US

International Classification:

C40B 30/06
C40B 40/02
C40B 50/06

US Classification:

506 10, 506 26, 506 14

Abstract:

Provided is a process for creating a 3D metabolically active microtissue perfused with living microvessels which have a direct fluidic connection with neighboring microfluidic channels. The process comprises preparing a template comprising a plurality of channels, and creating a network within said channels, said network comprising microfluidic channels, metabolically active living microvessels, and microtissues. The microvessels can sprout from said microvessels and/or form within the microtissue in response to a stimulus applied from said microfluidic channels or stimulus derived from the said tissues. In another embodiment, a device is provided comprising a supportive structure, one or more microfluidic channels, one or more microtissue compartments, and one or more microvessels, whereby the microvessels connect said microfludic channels and microtissue and perfuse the microtissue to deliver fluid from the microfluidic channels to the microtissues.

Address:

3379 Sheep Cyn St, Las Vegas, NV 89122

VIN:

4JVW013167A022099

Make:

Mercedes Benz

Model:

R-Class 4WD 4dr 6.3L AMG

Year:

2007