Mustafa Mah Maher

US Patent:

20120322727, Dec 20, 2012

Filed:

Jun 15, 2012

Appl. No.:

13/525176

Inventors:

Yaser A. Abdel Maksoud - Oak Lawn IL, US
Mustafa A. Maher - Phoenix AZ, US

International Classification:

A61K 38/28
A61P 25/28
A61K 31/47

US Classification:

514 65, 514311

Abstract:

In one embodiment of the invention, a pharmaceutical composition for intranasal administration comprises insulin, dimethyl sulfoxide and at least one pharmaceutically acceptable excipient. In another embodiment of the invention, a pharmaceutical composition for intranasal administration comprises clioquinol, dimethyl sulfoxide and at least one pharmaceutically acceptable excipient. In yet another embodiment of the invention, a pharmaceutical composition for intranasal administration comprises insulin, clioquinol, dimethyl sulfoxide and at least one pharmaceutically acceptable excipient. The pharmaceutical compositions of the invention may be used to treat or prevent a neurodegenerative disorder such as Alzheimer's disease, stroke, Parkinson's disease, multiple sclerosis, spinal cord injuries, and/or traumatic brain injuries and the like, in addition to other systemic and local diseases.