Nagabhushanam I Totakura

US Patent:

59391910, Aug 17, 1999

Filed:

Jun 23, 1997

Appl. No.:

8/880303

Inventors:

Steven L. Bennett - Southington CT
Ying Jiang - North Haven CT
Mark S. Roby - Killingworth CT
Nagabhushanam Totakura - North Haven CT

Assignee:

United States Surgical Corporation - Norwalk CT

International Classification:

B05D 136
A61B 1704

US Classification:

428375

Abstract:

A gut suture is coated with a bioabsorbable copolymer obtained by polymerizing a major amount of. epsilon. -caprolactone and a minor amount of at least one other copolymerizable monomer in the presence of polyhydric alcohol as initiator. The coated gut suture can be packaged in the absence of conventional tubing fluid, i. e. , in the dry state, while at the same time retaining flexibility, pliability and resistance to fray. In an alternative embodiment, a gut suture is coated with a pre-coating composition prior to being coated with the bioabsorbable copolymer.

US Patent:

59547480, Sep 21, 1999

Filed:

Jul 15, 1996

Appl. No.:

8/680387

Inventors:

Nagabhushanam Totakura - North Haven CT

Assignee:

United States Surgical Corporation - Norwalk CT

International Classification:

A61B 1704

US Classification:

606229

Abstract:

A catgut suture includes a cross linked gelatin coating which is substantially insoluble in tubing or storage solution. The gelatin coating is formed by immersing the gut suture in aqueous gelatin solution, fixing the gelatin in a solution of cross linking agent such as glutaraldehyde, buffering the coating, then drying the suture at a temperature of at least about 50. degree. C.

US Patent:

55848575, Dec 17, 1996

Filed:

Nov 14, 1994

Appl. No.:

8/338404

Inventors:

Nagabhushanam Totakura - North Haven CT
Shalaby W. Shalaby - Anderson SC
Lyudmila Kokish - Orange CT

Assignee:

United States Surgical Corporation - Norwalk CT

International Classification:

A61B 1704

US Classification:

606228

Abstract:

A coating and tubing fluid for sutures, especially gut sutures, is provided. The coating composition includes linseed oil, an organic solvent and a catalyst. The tubing fluid includes water, a softening agent, a C. sub. 2 -C. sub. 4 alcohol and a lubricant of fatty acids, fatty acid alcohols and/or triglycerides of fatty acids. Gut sutures coated with the coating composition may be stored or packaged in the tubing fluid to provide sutures with improved flexibility, pliability, run-down performance and superior resistance to fraying and breaking.

US Patent:

53839048, Jan 24, 1995

Filed:

Oct 13, 1992

Appl. No.:

7/959012

Inventors:

Nagabhushanam Totakura - Norwalk CT
Ross Muth - Brookfield, CT

Assignee:

United States Surgical Corporation - Norwalk CT

International Classification:

A61L 1700

US Classification:

606228

Abstract:

A suture-pledget combination is improved by applying a stiffening agent to at least a portion of the suture adjacent to the pledget to decrease the probability of tangling or twisting of the suture during use.

US Patent:

53586778, Oct 25, 1994

Filed:

Mar 17, 1992

Appl. No.:

7/852964

Inventors:

Ross R. Muth - Brookfield CT
Nagabhushanam Totakura - Norwalk CT
Keith D'Alessio - Warsaw IN

Assignee:

United States Surgical Corporation - Norwalk CT

International Classification:

B29B 1112
B29C 4314
B29C 4356

US Classification:

264 87

Abstract:

Method for forming polyvinyl alcohol (PVA) into surgical elements include forming a mixture of PVA and water into a film by vacuum pressing with a first force, heating, applying a second force two to two hundred times the firs force, drying the film to remove water to a content of less than about 10% by weight based on the weight of the film, and molding the film into a desired shape.

US Patent:

53229258, Jun 21, 1994

Filed:

Mar 19, 1993

Appl. No.:

8/033897

Inventors:

Ross R. Muth - Brookfield CT
Nagabhushanam Totakura - Norwalk CT
Cheng-Kung Liu - Norwalk CT

Assignee:

United States Surgical Corporation - Norwalk CT

International Classification:

C08G 6308
C08G 6300
A61M 1100

US Classification:

528354

Abstract:

Block copolymers have a first copolymer block wherein lactide is the predominant component and a second copolymer block wherein trimethylene carbonate is the predominant component. The copolymers are useful in forming surgical devices, including monofilament sutures.

US Patent:

53124375, May 17, 1994

Filed:

Jun 12, 1992

Appl. No.:

7/896856

Inventors:

Matthew E. Hermes - Easton CT
Donald S. Kaplan - Weston CT
Nagabhushanam Totakura - Norwalk CT
Steven L. Bennett - Milford CT

Assignee:

United States Surgical Corporation - Norwalk CT

International Classification:

A61L 1700

US Classification:

606230

Abstract:

An absorbable composition for application to a surgical suture to improve the knot tie-down and/or knot security characteristics thereof is obtained from the reaction of a poly(oxypropylene) glycol and a lactide/glycolide copolymer, optionally, in the presence of an initiator and/or catalyst.

US Patent:

52364445, Aug 17, 1993

Filed:

Oct 27, 1992

Appl. No.:

7/966948

Inventors:

Ross R. Muth - Brookfield CT
Nagabhushanam Totakura - Norwalk CT
Cheng-Kung Liu - Norwalk CT

Assignee:

United States Surgical Corporation - Norwalk CT

International Classification:

A61L 1700
C08G 6364
C08G 6308
C08G 6306

US Classification:

606230

Abstract:

Block copolymers have a first polymer block wherein glycolide is the predominant component and a second block having glycolide, lactide and trimethylene carbonate linkages. The copolymers are useful in forming surgical devices, including monofilament sutures.