Nan Ji from Arlington, MA, age 48

Resumes

Executive Director, Head Of Chemistry

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Location:

94 Beacon St, Somerville, MA 02143

Industry:

Biotechnology

Work:

Kymera Therapeutics May 2017 - Feb 2019
Director of Chemistry
Kymera Therapeutics May 2017 - Feb 2019
Executive Director, Head of Chemistry
Mitobridge, Inc. Apr 30, 2015 - May 15, 2017
Associate Director
Mitobridge, Inc. May 2015 - Jan 2016
Senior Scientist
Novartis Institutes For Biomedical Research (Nibr) May 1, 2008 - May 31, 2015
Investigator Iii

Education:

Harvard University 2000 - 2006
Doctorates, Doctor of Philosophy, Organic Chemistry Peking University 1996 - 2000
Bachelors, Bachelor of Science, Organic Chemistry High School Attached To Nenu

Skills:

Medicinal Chemistry
Drug Discovery
Organic Synthesis
Organic Chemistry
Drug Design
Chemistry
Synthetic Organic Chemistry
Lc Ms
Lead Change
Nmr
Kinases
Natural Products
High Throughput Screening
Biotechnology
Gpcrs
Life Sciences
Proteases
Adme
Fragment Based Drug Design
Natural Product Synthesis
Pharmaceutical Industry

Languages:

English
Mandarin

Research Analyst Ii

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Work:

Research Analyst Ii

Us Patents

Heterobicyclic Carboxamides As Inhibitors For Kinases
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US Patent:

8431584, Apr 30, 2013
Filed:

Jun 5, 2012
Appl. No.:

13/488760
Inventors:

Jason Matthew Elliott - Cambridge MA, US
Nan Ji - Cambridge MA, US
Donglei Liu - Cambridge MA, US
Fupeng Ma - Cambridge MA, US
Nello Mainolfi - Cambridge MA, US
Erik Meredith - Cambridge MA, US
Karl Miranda - Cambridge MA, US
James J. Powers - Cambridge MA, US
Chang Rao - Cambridge MA, US
Assignee:

Novartis AG - Basel
International Classification:

C07D 487/04
C07D 487/08
A61K 31/404
US Classification:

5142641, 544279
Abstract:

The invention relates to novel organic compounds of formula (I).

Heterobicyclic Carboxamides As Inhibitors For Kinases
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US Patent:

8486954, Jul 16, 2013
Filed:

Sep 13, 2012
Appl. No.:

13/613034
Inventors:

Jason Matthew Elliott - Cambridge MA, US
Nan Ji - Cambridge MA, US
Donglei Liu - Cambridge MA, US
Fupeng Ma - Cambridge MA, US
Nello Mainolfi - Cambridge MA, US
Erik Meredith - Cambridge MA, US
Karl Miranda - Cambridge MA, US
James J. Powers - Cambridge MA, US
Chang Rao - Cambridge MA, US
Assignee:

Novartis AG - Basel
International Classification:

C07D 487/04
C07D 487/08
A61K 31/404
A61P 27/02
US Classification:

5142641, 544279
Abstract:

The invention relates to novel organic compounds of formula (I).

Heterobicyclic Carboxamides As Inhibitors For Kinases
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US Patent:

8492393, Jul 23, 2013
Filed:

Sep 13, 2012
Appl. No.:

13/613019
Inventors:

Jason Matthew Elliott - Cambridge MA, US
Nan Ji - Cambridge MA, US
Donglei Liu - Cambridge MA, US
Fupeng Ma - Cambridge MA, US
Nello Mainolfi - Cambridge MA, US
Erik Meredith - Cambridge MA, US
Karl Miranda - Cambridge MA, US
James J. Powers - Cambridge MA, US
Chang Rao - Cambridge MA, US
Assignee:

Novartis AG - Basel
International Classification:

C07D 487/04
C07D 487/08
A61K 31/404
US Classification:

5142641, 544279
Abstract:

The invention relates to novel organic compounds of formula (I).

Heterobicyclic Carboxamides As Inhibitors For Kinases
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US Patent:

8501756, Aug 6, 2013
Filed:

Sep 13, 2012
Appl. No.:

13/613062
Inventors:

Jason Matthew Elliott - Cambridge MA, US
Nan Ji - Cambridge MA, US
Donglei Liu - Cambridge MA, US
Fupeng Ma - Cambridge MA, US
Nello Mainolfi - Cambridge MA, US
Erik Meredith - Cambridge MA, US
Karl Miranda - Cambridge MA, US
James J. Powers - Cambridge MA, US
Chang Rao - Cambridge MA, US
Assignee:

Novartis AG - Basel
International Classification:

C07D 487/04
C07D 487/08
A61K 31/404
A61P 27/02
US Classification:

514269, 544319
Abstract:

The invention relates to novel organic compounds of formula (I).

Heterobicyclic Carboxamides As Inhibitors For Kinases
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US Patent:

8541432, Sep 24, 2013
Filed:

Sep 13, 2012
Appl. No.:

13/613053
Inventors:

Jason Matthew Elliott - Cambridge MA, US
Nan Ji - Cambridge MA, US
Donglei Liu - Cambridge MA, US
Fupeng Ma - Cambridge MA, US
Nello Mainolfi - Cambridge MA, US
Erik Meredith - Cambridge MA, US
Karl Miranda - Cambridge MA, US
James J. Powers - Cambridge MA, US
Chang Rao - Cambridge MA, US
Assignee:

Novartis AG - Basel
International Classification:

C07D 487/04
C07D 487/08
A61K 31/404
A61P 27/02
US Classification:

514269, 544319
Abstract:

The invention relates to novel organic compounds of formula (I).

Heterobicyclic Carboxamides As Inhibitors For Kinases
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US Patent:

20100168082, Jul 1, 2010
Filed:

Dec 7, 2009
Appl. No.:

12/632396
Inventors:

Jason Matthew Elliott - Cambridge MA, US
Nan Ji - Cambridge MA, US
Donglei Liu - Cambridge MA, US
Fupeng Ma - Cambridge MA, US
Nello Mainolfi - Cambridge MA, US
Erik Meredith - Cambridge MA, US
Karl Miranda - Cambridge MA, US
James J. Powers - Cambridge MA, US
Chang Rao - Cambridge MA, US
International Classification:

A61K 31/55
C07D 403/14
A61K 31/506
A61K 31/4439
C07D 413/14
C07D 471/04
A61K 31/519
C07D 487/04
C07D 261/14
A61K 31/42
A61K 31/4155
C07D 403/04
US Classification:

514215, 544319, 514269, 514339, 5462721, 544279, 5142641, 540578, 548246, 514380, 514407, 5483641
Abstract:

The invention relates to novel organic compounds of formula (I)and their use in the treatment of the animal or human body, to pharmaceutical compositions comprising a compound of formula I and to the use of a compound of formula I for the preparation of pharmaceutical compositions for use in the treatment of protein kinase dependent diseases, especially of proliferative diseases, such as in the treatment of tumour diseases and ocular neovascular diseases.

Tetrahydropyrido-Pyridine And Tetrahydropyrido-Pyrimidine Compounds And Use Thereof As C5A Receptor Modulators
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US Patent:

20130184253, Jul 18, 2013
Filed:

Jul 19, 2012
Appl. No.:

13/553120
Inventors:

Christopher Michael ADAMS - Somerville MA, US
Veronique DARSIGNY - Somerville MA, US
Alec Nathanson FLYER - Cambridge MA, US
Christine Fang GELIN - Cambridge MA, US
Timothy Brian Hurley - Boston MA, US
Nan JI - Arlington MA, US
Rajeshri Ganesh KARKI - Somerville MA, US
Toshio KAWANAMI - Boston MA, US
Erik MEREDITH - Hudson MA, US
Chang RAO - Waltham MA, US
Michael H. SERRANO-WU - Belmont MA, US
Catherine Fooks SOLOVAY - Arlington MA, US
Assignee:

NOVARTIS AG - Basel
International Classification:

C07D 471/04
C07D 491/107
C07D 491/044
C07D 471/10
C07D 471/08
US Classification:

51421021, 5142342, 51425216, 51426411, 514300, 544117, 544230, 544279, 546122
Abstract:

The present invention provides a compound of formula I:(I)a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Complement Pathway Modulators And Uses Thereof
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US Patent:

20130296377, Nov 7, 2013
Filed:

Mar 14, 2013
Appl. No.:

13/826725
Inventors:

Christopher Michael ADAMS - Somerville MA, US
Charles BABU - Arlington TX, US
Michael Paul CAPPARELLI - Cambridge MA, US
Jian DING - Bedford MA, US
Takeru EHARA - Arlington MA, US
Keith JENDZA - Boston MA, US
Nan JI - Arlington MA, US
Rajeshri Ganesh KARKI - Somerville MA, US
Toshio KAWANAMI - Boston MA, US
Xue LIANG - Arlington TX, US
Nello MAINOLFI - Boston MA, US
James J. POWERS - Waltham MA, US
Michael H. SERRANO-WU - Belmont MA, US
Chun ZHANG - Waltham MA, US
International Classification:

C07D 491/048
A61K 31/4184
C07D 413/06
A61K 45/06
C07D 403/14
C07D 401/14
A61K 31/4439
C07D 403/06
A61K 31/423
US Classification:

514338, 5483051, 514394, 548217, 514375, 5462734, 548510, 548437
Abstract:

The present invention provides a compound of formula I: