Diane Harris Boschelli - New City NY Yanong Wang - Nanuet NY Frank Charles Boschelli - New City NY Dan Maarten Berger - New City NY Nan Zhang - Bayside NY Dennis William Powell - Cortlandt Manor NY Fei Ye - Nanuet NY Ayako Yamashita - Englewood NJ Frenel Fils DeMorin - Thousand Oaks CA Biqi Wu - Nanuet NY Elsebe Geraldine Overbeek-Klumpers - Bergentheim, NL Allan Wissner - Ardsley NY
This invention provides compounds of Formula (I), having the structure where T, Z, X, A, R , R , R , R , R , R , and n are defined herein, or a pharmaceutically acceptable salt thereof which are useful as antineoplastic agents and in the treatment of osteoporosis and polycystic kidney disease.
Dan M. Berger - New City NY Minu D. Dutia - West Nyack NY Frenel F. DeMorin - Nanuet NY Diane H. Boschelli - New City NY Dennis W. Powell - Westchester NY Allan Wissner - Ardsley NY Nan Zhang - Eastchester NY Fei Ye - Nanuet NY Biqi Wu - Nanuet NY
This invention provides compounds of formula 1, having the structure which are useful as inhibitors of protein tyrosine kinase and are antiproliferative agents.
3-Cyanoquinolines, 3-Cyano-1,6-Naphthyridines, And 3-Cyano-1,7-Naphthyridines As Protein Kinase Inhibitors
Diane Harris Boschelli - New City NY Yanong Wang - Nanuet NY Frank Charles Boschelli - New City NY Dan Maarten Berger - New City NY Nan Zhang - Bayside NY Dennis William Powell - Cortlandt Manor NY Fei Ye - Audubon PA Ayako Yamashita - Englewood NJ Frenel Fils DeMorin - Thousand Oaks CA Biqi Wu - Nanuet NY Elsebe Geraldine Overbeek-Klumpers - Baam, NL Allan Wissner - Ardsley NY
Assignee:
Wyeth - Madison NJ
International Classification:
A61K 3133
US Classification:
514183, 5142315, 514313, 514300, 514314, 546122
Abstract:
This invention provides compounds of Formula (I), having the structure where T, Z, X, A, R , R , R , R , R , R , and n are defined herein, or a pharmaceutically acceptable salt thereof which are useful as antineoplastic agents and in the treatment of osteoporosis and polycystic kidney disease.
Thieno[3,2-B]Pyridine-6-Carbonitriles And Thieno[2,3-B]Pyridine-5-Carbonitriles As Protein Kinase Inhibitors
Diane Harris Boschelli - New City NY, US Nan Zhang - Bayside NY, US Ana Carolina Barrios Sosa - Warwick NY, US Haris Durutlic - New Windsor NY, US Biqi Wu - Nanuet NY, US
Dan M. Berger - New City NY, US Minu D. Dutia - West Nyack NY, US Frenel F. DeMorin - Nanuet NY, US Diane H. Boschelli - New City NY, US Dennis W. Powell - Westchester NY, US Allan Wissner - Ardsley NY, US Nan Zhang - Eastchester NY, US Fei Ye - Nanuet NY, US Biqi Wu - Nanuet NY, US
Assignee:
WYETH - Madison NJ
International Classification:
A61K 31/44 C07D 471/04
US Classification:
514292, 546 81
Abstract:
This invention provides compounds of formula 1, having the structure.
Thieno[3,2-B]Pyridine-6-Carbonitriles And Thieno[2,3-B]Pyridine-5-Carbonitriles As Protein Kinase Inhibitors
Diane Harris Boschelli - New City NY, US Nan Zhang - Bayside NY, US Ana Carolina Barrios Sosa - Scotch Plains NJ, US Haris Durutlic - New Windsor NY, US Biqi Wu - Nanuet NY, US
Assignee:
Wyeth - Madison NJ
International Classification:
A61K 31/4365 C07D 495/06
US Classification:
514301, 546114
Abstract:
This invention provides compounds of Formula (1)–(1), II.
6-Aryl-7-Halo-Imidazo[1,2-A]Pyrimidines As Anticancer Agents
This invention relates to certain 6-aryl-7-halo-imidazo[1,2-a]pyrimidines or pharmaceutically acceptable salts thereof, and compositions containing said compounds or pharmaceutically acceptable salts thereof, wherein said compounds are anti-cancer agents useful for the treatment of cancer in mammals by promotion of microtubule polymerization. This invention further relates to a method of treating or inhibiting the growth of cancerous tumor cells and associated diseases in a mammal and further provides a method for the treatment or prevention of cancerous tumors that express multiple drug resistance (MDR) or are resistant because of MDR, in a mammal in need thereof which method comprises administering to said mammal an effective amount of said compounds or pharmaceutically acceptable salts thereof.
6-[(Substituted)Phenyl]Triazolopyrimidines As Anticancer Agents
Nan Zhang - Bayside NY, US Thai Nguyen - Fair Lawn NJ, US Yanzhong Wu - Bronx NY, US Wei Tong - Suffern NY, US
Assignee:
Wyeth - Madison NJ
International Classification:
C07D 487/04 A61K 31/519 A61P 35/04
US Classification:
5142593, 544263
Abstract:
This invention relates to certain 6-[(substituted)phenyl]triazolopyrimidine compounds or pharmaceutically acceptable salts thereof, and compositions containing said compounds or pharmaceutically acceptable salts thereof, wherein said compounds are anti-cancer agents useful for the treatment of cancer in mammals. This invention further relates to a method of treating or inhibiting the growth of cancerous tumor cells and associated diseases in a mammal and further provides a method for the treatment or prevention of cancerous tumors that express multiple drug resistance (MDR) or are resistant because of MDR, in a mammal in need thereof which method comprises administering to said mammal an effective amount of said compounds or pharmaceutically acceptable salts thereof. The present invention relates to a method of treating or inhibiting the growth of cancerous tumor cells and associated diseases in a mammal in need thereof by promotion of microtubule polymerization which comprises administering to said mammal an effective amount of said compounds and pharmaceutically acceptable salts thereof.
The Children's Hospital Corporation Hotels and Motels
342 Longwood Ave, Boston, MA 02115
Nan Zhang Lecturer/lighting Designer Theatre
The Trustees of The Smith College Colleges, Universities, and Professional Scho...
1 Chapin Way, North Hampton, MA 01063
Nan Zhang Treasurer
Sky Digital Holdings Corp
Nan Zhang Corporate Counsel/Legal
J P Morgan Mtg Acquisition Tr 2006-Wm Trusts, Nec
270 Park Ave, New York, NY 10017
Nan Zhang
CHENAN'S INC Nonclassifiable Establishments
40 Schenck Ave 3F, Great Neck, NY 11021 40 Schenck Ave, Great Neck, NY 11021
Nan Zhang Assistant Professor
University of Texas at Austin College/University · University · Social Services College/University · Noncommercial Research Organization College/University · School/Educational Services · Membership Sport/Recreation Club College/University · Help Supply Services College/University · Chemical Engineering Education
Dept. of Gene and Cell Medicine New York, NY Mar 2006 to Jun 2008 Instructor ScientistDept. of Gene and Cell Medicine New York, NY Aug 2001 to Feb 2006 Postdoctoral FellowQilu Hospital, Shandong University China, ME Jul 1999 to Jul 2001 Attending surgeon, Assistant Professor
Education:
Marshall University, Joan C. Edwards School of Medicine Huntington, WV 2009 to 2013 Surgery ResidentUniversity of Kentucky, School of Medicine Lexington, KY Nov 2011 to Dec 2011 Surgery ResidentSt Mary Medical Center and Huntington VA Medical Center Huntington, VA 2008 to 2009 Surgery InternShandong University Medical School China, ME 1994 to 1999 SurgeryMedical School of Shandong University Jul 1994 Doctor of MedicineMarshall University, Joan C. Edwards School of Medicine Huntington, WV 2013 Chief surgery resident
Skills:
Complex upper GI/colorectal surgery, minimally invasive surgery, breast surgery and vascular surgery
Other contributors to this work include Nan Zhang, Meng Yu, Qianru Zhao, Bing Feng, Yue Deng, Jonathan C. Bean, Qingzhuo Liu, Benjamin P. Eappen, Yang He, Kristine M. Conde, Hailan Liu, Yongjie Yang, Longlong Tu, Mengjie Wang, Yongxiang Li, Na Yin, Hesong Liu, Junying Han, Darah Ave Threat, Nathan X
Date: Mar 25, 2025
Category: Health
Source: Google
The Moon Turned Itself Inside Out, Scientists Confirm
Pointing to a 2022 study conducted by Chinese researcher Nan Zhang who is now a co-author on the recent paper and hypothesizing that some past impact to the Moon may have pushed the titanium-heavy minerals to its core, Andrews-Hanna said that a "lightbulb went on."
Using ReFRAME, the teamwhich also includes Scripps Research and Calibr-Skaggs researchers Sida Shao, Nan Zhang, Sean B. Joseph, Arnab K. Chatterjee and Jeffrey Jian Chendetermined that a drug class known as DPP4 inhibitors could potentially help activate production of lower airway stem cells, call
He and co-author Nan Zhang, also of the University of Manchester, decided to test it. They surveyed 1,116 people in the UK aged 35 to 75 years and found that those who transitioned from unemployment to a poor-quality job had higher biological indicators of stress than people who remained unemployed.
Nan Zhang (2003-2007), Belal Elashi (2000-2004), Utomobong Akpan (2002-2006), Susan Sigouin (1977-1981), Robert Larabie (1971-1975), Barry Strachan (1973-1977)
Googleplus
Nan Zhang
Bragging Rights:
Working hard
Nan Zhang
Education:
THU - EE, PSU - IST
Nan Zhang
Nan Zhang
Education:
Massey University - I.T
Nan Zhang
Education:
Virginia Polytechnic Institute and State University