Nan Zhang

US Patent:

20120294904, Nov 22, 2012

Filed:

May 18, 2012

Appl. No.:

13/474749

Inventors:

Rebecca A. Bader - Syracuse NY, US
Nan Zhang - Syracuse NY, US

Assignee:

SYRACUSE UNIVERSITY - Syracuse NY

International Classification:

A61K 31/726
A61K 9/00
B82Y 15/00

US Classification:

424400, 514 55, 977773, 977840

Abstract:

Gel nanoparticles for encapsulating and delivering a pharmaceutical compound to a patient. The nanoparticles are formed from N-trimethyl chitosan and polysialic acid, preferably in the presence of sodium tripolyphosphate. A ratio of polysialic acid to N-trimethyl chitosan of about 0.5 to 1 produces nanoparticles having diameter of about 100 nm (plus or minus 25 nm) and a zero potential above 30 milivolts that can stability contain a pharmaceutical compound, such as methotrexate, for delivery to a patient.

US Patent:

20220349087, Nov 3, 2022

Filed:

Apr 27, 2022

Appl. No.:

17/730742

Inventors:

- Hsinchu, TW
Parthiv Daggolu - Gloucester MA, US
Soubir Basak - Chandler AZ, US
Nan Zhang - O'Fallon MO, US

International Classification:

C30B 15/36
C30B 15/22
C30B 15/30
C30B 15/14

Abstract:

Method for producing a silicon ingot in which a horizontal magnetic field is generated are disclosed. A plurality of process parameters are regulated during ingot growth including a wall temperature of the crucible, a transport of silicon monoxide (SiO) from the crucible to the single crystal, and an evaporation rate of SiO from the melt. Regulating the plurality of process parameters may include controlling the position of a maximum gauss plane of the horizontal magnetic field, controlling the strength of the horizontal magnetic field, and controlling the crucible rotation rate.